Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Peter Seiron"'
Autor:
Peter Seiron, Anna Wiberg, Enida Kuric, Lars Krogvold, Frode L Jahnsen, Knut Dahl‐Jørgensen, Oskar Skog, Olle Korsgren
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 5, Iss 4, Pp 248-255 (2019)
Abstract Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the nu
Externí odkaz:
https://doaj.org/article/1450ebcefbad401eabb1eb9e28af68f6
Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes
Autor:
Louise Granlund, Anders Hedin, Miriam Wahlhütter, Peter Seiron, Olle Korsgren, Oskar Skog, Marcus Lundberg
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Despite a reduced function and volume of the exocrine pancreas in type 1 diabetes, the acinar cells remain understudied in type 1 diabetes research. The hypothesis of this study is that the acinar tissue is altered in subjects with type
Externí odkaz:
https://doaj.org/article/a0f0343636c94b669ecd14896db7fa09
Autor:
Peter Seiron, Anton Stenwall, Anders Hedin, Louise Granlund, Jonathan Lou S Esguerra, Petr Volkov, Erik Renström, Olle Korsgren, Marcus Lundberg, Oskar Skog
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247888 (2021)
Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased
Externí odkaz:
https://doaj.org/article/ba5065644b6941a5a6a040ac543cc68b
Autor:
Oskar Skog, Anton Stenwall, Petr Volkov, Jonathan L.S. Esguerra, Olle Korsgren, Louise Granlund, Marcus Lundberg, Peter Seiron, Anders Hedin, Erik Renström
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247888 (2021)
PLoS ONE
PLoS ONE
Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9846de835000f8491f71ecbb2494bff
https://doaj.org/article/ba5065644b6941a5a6a040ac543cc68b
https://doaj.org/article/ba5065644b6941a5a6a040ac543cc68b
Autor:
Olle Korsgren, Knut Dahl-Jørgensen, Oskar Skog, Anna Wiberg, Frode L. Jahnsen, Peter Seiron, Lars Krogvold
Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of specific beta-cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size if the beta cells are not replaced by othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48851490b1c5aee2e5957982ff762661
https://doi.org/10.1101/480509
https://doi.org/10.1101/480509
Autor:
Folke Knutson, Peter Seiron, Marcus Bergström, Per-Anton Stenwall, Felix Sellberg, Tobias Olsson, David Berglund
Publikováno v:
Acta Ophthalmologica. 93:654-657
Purpose To investigate the cytokine composition and anti-inflammatory effects of allogeneic serum preparations for improved use as serum eye drops. Methods Serum of 15 healthy blood donors was extensively screened for cytokines, including IL-1β, IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4936bc568d1d1740fe54a1e710bc1631
https://doi.org/10.1111/aos.12801
https://doi.org/10.1111/aos.12801
Publikováno v:
Diabetologia
Aims/hypothesis According to the consensus criteria developed for type 1 diabetes, an individual can be diagnosed with insulitis when ≥ 15 CD45+ cells are found within the parenchyma or in the islet–exocrine interface in ≥ 3 islets. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f140a2424404580a5e3eaa7e2daad19a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-315054
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-315054
Autor:
Trond Buanes, Enida Kuric, Lars Krogvold, Knut Dahl-Jørgensen, Peter Seiron, Kristian F. Hanssen, Bjørn Edwin, Olle Korsgren, Oskar Skog
Subtypes of CD8 + T cells in insulitic lesions in biopsy specimens from six subjects with recent-onset type 1 diabetes (T1D) and six nondiabetic matched controls were analyzed using simultaneous multicolor immunofluorescence. Also, insulitic islets b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be74cc6893dbc4cb47e986d3479ac569
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-318323
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-318323
Publikováno v:
Diabetologia. 60:756-757
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes : is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7343d8c45a87023825bebfcdc1edee1b
https://doi.org/10.1007/s00125-017-4212-8
https://doi.org/10.1007/s00125-017-4212-8
Autor:
Anne-Laure Joly, E. Modig, Marcus Bergström, David Berglund, Bengt Fellström, Peter Seiron, John Andersson, S. Isringhausen
Publikováno v:
Scandinavian journal of immunology. 81(5)
With the increasing interest in clinical trials with regulatory T cells (Tregs), immunological profiling of prospective target groups and standardized procedures for Treg isolation are needed. In this study, flow cytometry was used to assess peripher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7bd89bb99fc422df974a4dfbf6c6cd
https://pubmed.ncbi.nlm.nih.gov/25737071
https://pubmed.ncbi.nlm.nih.gov/25737071