Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Peter Seideman"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 49:200-204
Barbiturate treatment can enhance drug oxidation in man, but its effects on glucuronidation of clinically used drugs are unknown. We have studied the effect of 10 days treatment with pentobarbital on oxazepam glucuronidation in six volunteers. The di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4657d02039f1e93fc17ac1a89cfc282
https://doi.org/10.1111/j.1600-0773.1981.tb00893.x
https://doi.org/10.1111/j.1600-0773.1981.tb00893.x
Autor:
Olof Beck, Peter Seideman, Freidoun Albertioni, Carsten Peterson, Charlotte Ulrikka Rask, Birgitta Pettersson
Publikováno v:
Albertioni, F, Pettersson, B, Beck, O, Rask, C, Seideman, P & Peterson, C 1995, ' Simultaneous quantitation of methotrexate and its two main metabolites in biological fluids by a novel solid-phase extraction procedure using high-performance liquid chromatography ', Journal of Chromatography B: Biomedical Sciences and Applications, vol. 665, no. 1, pp. 163-170 . https://doi.org/10.1016/0378-4347(94)00507-2
We have developed an assay for the simultaneous determination of methotrexate (MTX) and its main metabolites, 7-hydroxymethotrexate (7-OHMTX) and 2,4-diamino-N10-methylpteroic acid (DAMPA) in plasma, urine and saliva meeting the requirement of rapidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8024b83116e4d827e2b3c4981d1ccb3
https://doi.org/10.1016/0378-4347(94)00507-2
https://doi.org/10.1016/0378-4347(94)00507-2
Publikováno v:
Therapeutic Drug Monitoring. 16:560-563
Summary A limited sampling strategy for determination of the area under the plasma concentration versus time curve (AUC) of methotrexate (MTX) in patients with rheumatoid arthritis (RA), treated with weekly oral doses, has been validated. Stepwise li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc666ceb150b81abca8d1a59ef64621
https://doi.org/10.1097/00007691-199412000-00005
https://doi.org/10.1097/00007691-199412000-00005
The stereoselective disposition of the enantiomers of ibuprofen in blood, blister and synovial fluid
Publikováno v:
British Journal of Clinical Pharmacology. 38:221-227
1. A sensitive, stereospecific assay using gas chromatography-mass spectrometry (GC/MS) was established to measure the concentrations of the enantiomers of ibuprofen in small volumes (50 microliters) of blister fluid. 2. The concentrations of the ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf521f7c329b33b01e73b2c0cb10e124
https://doi.org/10.1111/j.1365-2125.1994.tb04345.x
https://doi.org/10.1111/j.1365-2125.1994.tb04345.x
Publikováno v:
Arthritis & Rheumatism. 37:830-833
Objective To evaluate the effects of a single dose of chloroquine (CQ) on the pharmacokinetics of methotrexate (MTX) in patients with rheumatoid arthritis. Methods Eleven patients (ages 41-75 years) who were taking oral doses of MTX (15 mg/week) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aeeabc3bf396eda46423cf36f572368
https://doi.org/10.1002/art.1780370609
https://doi.org/10.1002/art.1780370609
Publikováno v:
British Journal of Clinical Pharmacology. 35:409-412
1. The pharmacokinetics of MTX and its 7-hydroxy metabolite (7-OHMTX) were investigated in nine patients with rheumatoid arthritis (RA). Each patient received 15 mg MTX i.v., i.m. and p.o. after an overnight fast in a randomized cross-over design. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9072a6d708f1255e9aa7cb75510cfa8b
https://doi.org/10.1111/j.1365-2125.1993.tb04158.x
https://doi.org/10.1111/j.1365-2125.1993.tb04158.x
Autor:
Peter Seideman
Publikováno v:
The Journal of Clinical Pharmacology. 31:804-807
Paracetamol is an analgetic drug with additive effect if combined with indomethacin. In rat experiments, paracetamol has been shown to be gastro-protective, and in animal experiments, indomethacin blood levels decreased during combined treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068163662766382fc6bc24990a4fd538
https://doi.org/10.1002/j.1552-4604.1991.tb01915.x
https://doi.org/10.1002/j.1552-4604.1991.tb01915.x
Publikováno v:
European Journal of Clinical Pharmacology. 47
Children with juvenile rheumatoid arthritis (JRA) have been reported to require higher doses (per kg body weight) of methotrexate (MTX) than adults with rheumatoid arthritis to control their disease. The purpose of the present study was to characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bcfa1b5cefe48ab99e8f28b82048ce
https://doi.org/10.1007/bf00193703
https://doi.org/10.1007/bf00193703
Publikováno v:
Journal of pharmaceutical sciences. 82(8)
After a single oral dose of (R,S)-ibuprofen (1200 mg) to five healthy volunteers, paired plasma and blister fluid concentrations of drug were determined by a stereospecific HPLC assay. A pharmacokinetic model that incorporated blister fluid as a sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5f95809089e0fc6f6fefd5b6925131
https://pubmed.ncbi.nlm.nih.gov/8377114
https://pubmed.ncbi.nlm.nih.gov/8377114
Publikováno v:
Acta orthopaedica Scandinavica. 64(3)
In a double-blind study of 18 patients with coxarthrosis the effect of 3 naproxen doses (0.5, 1.0, and 1.5 g daily) and 2 naproxen doses combined with paracetamol (0.5 g + 4 g daily and 1.0 g + 4 g daily) was investigated. Plasma levels of naproxen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba48f55997c0e710e2671f1c34f65c8
https://pubmed.ncbi.nlm.nih.gov/8322582
https://pubmed.ncbi.nlm.nih.gov/8322582