Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Peter Scott Mountford"'
Publikováno v:
Cloning and Stem Cells. 4:121-130
Totipotency can be restored to the nuclei of somatic cells by reprogramming the nucleus via the technique of nuclear transfer. As genes expressed in somatic cells differ from those expressed in early embryos, a change in gene expression must accompan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ec91f7b73b2bc3db8b0c1a648b82ef
https://doi.org/10.1089/153623002320253300
https://doi.org/10.1089/153623002320253300
Autor:
Carmel M. O’Brien, Martin F. Pera, Alan O Trounson, Anna E. Michalska, Megan Munsie, Peter Scott Mountford
Publikováno v:
Current Biology. 10(16):989-992
Pluripotent human stem cells isolated from early embryos represent a potentially unlimited source of many different cell types for cell-based gene and tissue therapies [1–3]. Nevertheless, if the full potential of cell lines derived from donor embr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89341a547200557640153cbeedfd1f4
Autor:
Peter Scott Mountford, Austin Smith
Publikováno v:
Trends in Genetics
Modification of the genetic content of cultured cells or of whole animals is now a key strategy in both basic biological research and applied biotechnology. Yet obtaining the desired level and specificity of expression of an introduced gene remains h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03845670fa0f448caa6b1b17dfcab5c
https://doi.org/10.1016/s0168-9525(00)89040-x
https://doi.org/10.1016/s0168-9525(00)89040-x
Publikováno v:
Journal of Neuroendocrinology. 4:655-658
The influence of the 3'untranslated (3'-UT) region of the ovine follicle-stimulating hormone (FSH) β mRNA on the level of transcript expression was studied. Only very low levels of FSH β mRNA were detected following transient transfection of COS ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d7c0390aa6d46cc52bc6a84e97946a
https://doi.org/10.1111/j.1365-2826.1992.tb00215.x
https://doi.org/10.1111/j.1365-2826.1992.tb00215.x
Transgenic reporters have proved to be invaluable in the study of nuclear reprogramming, from demonstrating revival or silencing of gene expression in fusion hybrids to providing a means to display levels and distribution of specific gene products af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67907501beb0084d764f70ed354d4e5a
https://doi.org/10.1385/1-59745-005-7:115
https://doi.org/10.1385/1-59745-005-7:115
Publikováno v:
Scopus-Elsevier
Confirmation of nuclear contribution is essential to all nuclear transfer experiments. Contribution is easily demonstrated in nuclear transfer progeny but more difficult to confirm in nuclear transfer embryos. The use of donor nuclei isolated from la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed50e2903d1e7ec7c2509ad85cfb690c
https://pubmed.ncbi.nlm.nih.gov/10612469
https://pubmed.ncbi.nlm.nih.gov/10612469
Publikováno v:
Gene. 197(1-2)
Use of EBV-based vector systems has been limited by the requirement to generate EBNA+ cells which are 'permissive' for replication of an oriP -vector. In current constructs, selectable marker and EBNA-1 are not always co-expressed. This is a signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b926fd5c6e69aa008e8f75c8a449d80
https://pubmed.ncbi.nlm.nih.gov/9332352
https://pubmed.ncbi.nlm.nih.gov/9332352
Autor:
Branko Zevnik, Meng Li, Austin Smith, Ian Chambers, Christian Dani, Morag Robertson, Peter Scott Mountford, Annette Duwel, Jennifer Nichols
Publikováno v:
Scopus-Elsevier
To investigate the activity of candidate regulatory molecules in mammalian embryogenesis, we have developed a general strategy for modifying and reporting resident chromosomal gene expression. The picornaviral internal ribosome-entry site was incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e1856fa8b11c19ce609cc279c21693
https://pubmed.ncbi.nlm.nih.gov/8183905
https://pubmed.ncbi.nlm.nih.gov/8183905
Publikováno v:
Reproduction, Fertility and Development. 10:683
The transplantation of organs and tissues between animal species, or xenotransplantation, is the focus of a growing field of research, owing primarily to the increasing shortage of allogeneic donor organs. The pig stands out as the most suitable dono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23680f3264cb6080fb86479ef496319
https://doi.org/10.1071/rd98112
https://doi.org/10.1071/rd98112
Publikováno v:
Nucleic acids research. 17(24)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43e4bf992d6baca6ff8382100f5d57a
https://pubmed.ncbi.nlm.nih.gov/2481272
https://pubmed.ncbi.nlm.nih.gov/2481272