Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Peter Schulz-Knappe"'
Autor:
Stefan Vordenbäumen, Ralph Brinks, Patrick Schriek, Angelika Lueking, Jutta G. Richter, Petra Budde, Peter Schulz-Knappe, Hans-Dieter Zucht, Johanna Callhoff, Matthias Schneider
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Objective To assess the diagnostic potential of IgG antibodies to citrullinated and corresponding native autoantigens in early arthritis. Methods IgG autoantibodies to 390 distinct unmodified and corresponding in vitro citrullinated recombin
Externí odkaz:
https://doaj.org/article/e1e3b9fc93564e8c97ef88ca203b71f5
Publikováno v:
EuPA Open Proteomics, Vol 3, Iss C, Pp 171-182 (2014)
Peptides have been studied for over 100 years, but for most of this time the focus was on a specific peptide or peptides, and not on the general peptidome of a biological sample. In the 1990s, mass spectrometry techniques were developed for the analy
Externí odkaz:
https://doaj.org/article/24888d89e66e44bbaf114d4279df8e41
Autor:
Bettina Schlick, Petra Massoner, Angelika Lueking, Pornpimol Charoentong, Mirjam Blattner, Georg Schaefer, Klaus Marquart, Carmen Theek, Peter Amersdorfer, Dirk Zielinski, Matthias Kirchner, Zlatko Trajanoski, Mark A Rubin, Stefan Müllner, Peter Schulz-Knappe, Helmut Klocker
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147739 (2016)
BACKGROUND:Chronic inflammation is frequently observed on histological analysis of malignant and non-malignant prostate specimens. It is a suspected supporting factor for prostate diseases and their progression and a main cause of false positive PSA
Externí odkaz:
https://doaj.org/article/215138ae05eb455fb9dd2c9ae1784c83
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Stephan Jung, Dennis Friedel, Ines Heiland, Tobias Bausbacher, Christiane A. Opitz, Stefan Selzer, Ian Pike, Andreas von Deimling, Antje Wick, Karsten Kuhn, Suraj Sharma, Verena Panitz, Irada Pflüger, Sandra Schulz, Wolfgang Wick, Philipp Vollmuth, Sasa Koncarevic, Philipp Sievers, Saskia Trump, Stefan Schmidt, Carsten Hopf, Felix Sahm, Peter Schulz-Knappe, Michael Platten, V. M. Farztdinov, Pauline Pfänder, Ina Jürgenson, Ahmed Sadik
Publikováno v:
Theranostics
Tryptophan (Trp)-catabolic enzymes (TCEs) produce metabolites that activate the aryl hydrocarbon receptor (AHR) and promote tumor progression and immunosuppression in glioblastoma. As therapies targeting TCEs or AHR become available, a better underst
Autor:
Nisha Nair, Hans-Dieter Zucht, Petra Budde, Suzanne M M Verstappen, Stephanie Ling, Anne Barton, Darren Plant, Peter Schulz-Knappe
Publikováno v:
Ling, S, Nair, N, Verstappen, S, Barton, A, Zucht, H-D, Budde, P, Schulz-Knappe, P, MATURA, & Plant, D 2020, ' Proteomic analysis to define predictors of treatment response to adalimumab or methotrexate in rheumatoid arthritis patients ', The Pharmacogenomics Journal, pp. 1-8 . https://doi.org/10.1038/s41397-019-0139-4
The Pharmacogenomics Journal
The Pharmacogenomics Journal
Seropositivity for anti-citrullinated peptide antibodies (ACPA) in patients with rheumatoid arthritis (RA), a chronic autoimmune arthritis, is associated with worse long-term disease outcomes. ACPA is ubiquitously tested in RA patients, but other aut
Autor:
Matthias Schneider, Ralph Brinks, Petra Budde, Peter Schulz-Knappe, Stefan Vordenbäumen, Hans-Dieter Zucht, Ellen Bleck, Georg Pongratz, Rebecca Fischer-Betz, Annika Hoyer, Torsten Lowin
Publikováno v:
Arthritis & Rheumatology. 71:736-743
OBJECTIVE To investigate the role of epitope spreading in established systemic lupus erythematosus (SLE). METHODS IgG autoantibody reactivity with 398 distinct recombinant proteins was measured over a period of 6 years in 69 SLE patients and compared
Autor:
Stefan Müllner, Johannes Schulte-Pelkum, Benjamin L. Miller, Christopher C. Striemer, Jared A. Carter, Joseph Bucukovski, Peter Schulz-Knappe
Publikováno v:
Journal of Immunological Methods. 459:44-49
Multiplex assays for autoantibodies have shown utility both in research towards understanding the basic biology of autoimmune disease, and as tools for clinical diagnosis. New label-free multiplex analysis methods have the potential to streamline bot
Autor:
Heike Göhler, Matthias Schneider, Ellen Bleck, Petra Budde, Ralph Brinks, Hans-Dieter Zucht, Petra Rengers, Peter Schulz-Knappe, Jutta G Richter, Rebecca Fischer-Betz, Paloma Böhmer, Stefan Vordenbäumen
Publikováno v:
Rheumatology. 57:533-537
Objective Diagnosis of SLE relies on the detection of autoantibodies. We aimed to assess the diagnostic potential of histone H4 and H2A variant antibodies in SLE. Methods IgG-autoantibodies to histones H4 (HIST1H4A), H2A type 2-A (HIST2H2AA3) and H2A
Autor:
Angelika Lueking, Carmen Theek, Laura Schlieker, Katja Ickstadt, Anna Telaar, Peter Schulz-Knappe
Publikováno v:
Biometrical Journal. 59:948-966
The classification of a population by a specific trait is a major task in medicine, for example when in a diagnostic setting groups of patients with specific diseases are identified, but also when in predictive medicine a group of patients is classif