Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter Schettina"'
Autor:
Parisa Kakanj, Karen Reuter, Gilles Séquaris, Claudia Wodtke, Peter Schettina, Daniela Frances, Christos C. Zouboulis, Beate Lanske, Catherin Niemann
Publikováno v:
Cell Reports, Vol 4, Iss 2, Pp 340-351 (2013)
Mutations in the hedgehog pathway drive the formation of tumors in many different organs, including the development of basal cell carcinoma in the skin. However, little is known about the role of epidermal Indian hedgehog (Ihh) in skin physiology. Us
Externí odkaz:
https://doaj.org/article/88b9aa4be13a4270b02cf8726abde222
The NH2 terminus of LEF1 is frequently mutated in human sebaceous tumors. To investigate how this contributes to cancer, we did two-stage chemical carcinogenesis on K14ΔNLef1 transgenic mice, which express NH2-terminally truncated Lef1 in the epider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7b5eb1ab957cafd58054a98820291d
https://doi.org/10.1158/0008-5472.c.6495824
https://doi.org/10.1158/0008-5472.c.6495824
Supplementary Table 1 from Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specification of Tumor Type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38baceed6b2397f599d48c80b4eb986f
https://doi.org/10.1158/0008-5472.22368128
https://doi.org/10.1158/0008-5472.22368128
Supplementary Information from Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specification of Tumor Type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435594886ff676eb4793fed1625d561b
https://doi.org/10.1158/0008-5472.22368131.v1
https://doi.org/10.1158/0008-5472.22368131.v1
Autor:
Catherin Niemann, Florian Kuester, Peter Schettina, Giada Mantellato, Hamid Kashkar, Anna Geueke, Melanie Nelles, Jens M. Seeger
Publikováno v:
EMBO Reports
Maintaining the architecture, size and composition of an intact stem cell (SC) compartment is crucial for tissue homeostasis and regeneration throughout life. In mammalian skin, elevated expression of the anti‐apoptotic Bcl‐2 protein has been rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afba912f30cb0145c967ba0eaa6eb23a
https://pubmed.ncbi.nlm.nih.gov/34342114
https://pubmed.ncbi.nlm.nih.gov/34342114
Autor:
Catherin Niemann, Peter Schettina, Heike Brylka, Andreas Kraus, Susan D. John, Gunter Rappl, Monika Petersson
Publikováno v:
The EMBO Journal. 30:3004-3018
Mammalian epidermis consists of the interfollicular epidermis, hair follicles (HFs) and associated sebaceous glands (SGs). It is constantly renewed by stem and progenitor cell populations that have been identified and each compartment features a dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2300d8e7438e3cd30fca38082446924
https://doi.org/10.1038/emboj.2011.199
https://doi.org/10.1038/emboj.2011.199
Autor:
Konrad Sandhoff, Bernadette Breiden, Carien M. Niessen, Susanne Brodesser, Wilhelm Bloch, Uwe Galli, Catherin Niemann, Christian Günschmann, Peter Schettina, Christian Michels, Dagmar Fehrenschild
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology; Vol 132
Journal of Investigative Dermatology; Vol 132
Defects in the function of the skin barrier are associated with a wide variety of skin diseases, many of which are not well characterized at the molecular level. Using Lef1 (lymphoid enhancer-binding factor 1) dominant-negative mutant mice, we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914beb7a874bf85c366804b9b71ac30d
Autor:
Peter Schettina, Catherin Niemann, Heike Brylka, Andreas Kraus, Karen Reuter, Monika Petersson
Publikováno v:
Nature Communications
Epithelial cancer constitutes a major clinical challenge and molecular mechanisms underlying the process of tumour initiation are not well understood. Here we demonstrate that hair follicle bulge stem cells (SCs) give rise to well-differentiated seba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f08390c374d8c0cbf986950f12ca064
https://doi.org/10.1038/ncomms6874
https://doi.org/10.1038/ncomms6874
Autor:
Karen Reuter, Gilles Séquaris, Claudia Wodtke, Daniela Frances, Catherin Niemann, Parisa Kakanj, Beate Lanske, Christos C. Zouboulis, Peter Schettina
Publikováno v:
Cell Reports, Vol 4, Iss 2, Pp 340-351 (2013)
SummaryMutations in the hedgehog pathway drive the formation of tumors in many different organs, including the development of basal cell carcinoma in the skin. However, little is known about the role of epidermal Indian hedgehog (Ihh) in skin physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a662b40017ea3856817f8a42e411845