Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Peter Schell"'
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 7, Pp o1028-o1028 (2013)
The title compound, C12H20N4O, undergoes a phase transition on cooling. The room-temperature structure is tetragonal (P43212, Z′ = 1), with the methoxybornyl group being extremely disordered. Below 213 K the structure is orthorhombic (P212121, Z′
Externí odkaz:
https://doaj.org/article/463797dd57eb466889e081f792b649dd
Autor:
Brijesh V. Patel, Sharon Mumby, Nicholas Johnson, Rhodri Handslip, Sunil Patel, Teresa Lee, Martin S. Andersen, Emanuela Falaschetti, Ian M. Adcock, Danny F. McAuley, Masao Takata, Thomas Staudinger, Dan S. Karbing, Matthieu Jabaudon, Peter Schellongowski, Stephen E. Rees, On behalf of the DeVENT Study Group
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundAcute respiratory distress syndrome (ARDS) is highly heterogeneous, both in its clinical presentation and in the patient’s physiological responses to changes in mechanical ventilator settings, such as PEEP. This study investigates the cli
Externí odkaz:
https://doaj.org/article/12347a73c95f40a79c8cc08f56756218
Autor:
Carolina Secreto, Dara Chean, Andry van de Louw, Achille Kouatchet, Philippe Bauer, Marco Cerrano, Etienne Lengliné, Colombe Saillard, Laurent Chow-Chine, Anders Perner, Peter Pickkers, Marcio Soares, Jordi Rello, Frédéric Pène, Virginie Lemiale, Michael Darmon, Sofiane Fodil, Ignacio Martin-Loeches, Sangeeta Mehta, Peter Schellongowski, Elie Azoulay, Djamel Mokart
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Acute respiratory failure (ARF) is the leading cause of intensive care unit (ICU) admission in patients with Acute Myeloid Leukemia (AML) and data on prognostic factors affecting short-term outcome are needed. Methods This is a po
Externí odkaz:
https://doaj.org/article/0cb93d27e9f74cf095f54e7548f2cb5d
Autor:
Robert J. Sheppard, Peter Schell, Eelke B. Lenselink, Leifeng Cheng, Laura H. Heitman, Adriaan P. IJzerman, Henk de Vries, Maria J. Petersson, Roine I. Olsson, Sara Pahlén, Michael J. Waring, Lizi Xia, Julien Louvel
Publikováno v:
Journal of Medicinal Chemistry
JOURNAL OF MEDICINAL CHEMISTRY, 60(23), 9545-9564
JOURNAL OF MEDICINAL CHEMISTRY
JOURNAL OF MEDICINAL CHEMISTRY, 60(23), 9545-9564
JOURNAL OF MEDICINAL CHEMISTRY
We report on the synthesis and biological evaluation of a series of 1,2-diarylimidazol-4-carboxamide derivatives developed as CB1 receptor antagonists. These were evaluated in a radioligand displacement binding assay, a [35S]GTPγS binding assay, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff212f527a82b848d9f47dfc77c4462a
https://hdl.handle.net/1887/58213
https://hdl.handle.net/1887/58213
Autor:
Lucas Boeck, Hans Pargger, Peter Schellongowski, Charles-Edouard Luyt, Marco Maggiorini, Kathleen Jahn, Grégoire Muller, Rene Lötscher, Evelyne Bucher, Nadine Cueni, Thomas Staudinger, Jean Chastre, Martin Siegemund, Michael Tamm, Daiana Stolz
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-10 (2023)
Abstract Background ICU risk assessment tools, routinely used for predicting population outcomes, are not recommended for evaluating individual risk. The state of health of single patients is mostly subjectively assessed to inform relatives and presu
Externí odkaz:
https://doaj.org/article/6634832db8a54bea804fda3b41e92590
Autor:
Daniel Aletaha, Peter Schellongowski, Michael Zauner, Klaus P Machold, Gottfried Heinz, Thomas Staudinger, Christian Zauner, Gürkan Sengölge, Mathias Schneeweiss-Gleixner, Caroline Hillebrand, Stephanie Jaksits, Jonathan Fries, Manuel Bécède
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objectives Patients with systemic rheumatic diseases (SRDs) are at risk of admission to the intensive care unit (ICU). Data concerning these critically ill patients are limited to few retrospective studies.Methods This is a single-centre retrospectiv
Externí odkaz:
https://doaj.org/article/0ec076d223234dce8780487f8d11ff0f
Autor:
Andrea Kornfehl MD, Roman Brock MD, Thomas Staudinger MD, Peter Schellongowski MD, Bernhard Nagler MD, Alexander Hermann MD, PhD, Oliver Robak MD, Michael Schwameis MD, Peter Quehenberger MD, Nina Buchtele MD, PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Background Monitoring of blood coagulation is essential in ECMO patients. We investigated the prevalence of lupus anticoagulant (LA) and its association with coagulation testing and hemostaseologic complications in patients treated with ECMO. Methods
Externí odkaz:
https://doaj.org/article/df1524a5644f4885acea6a6ce2c05703
Autor:
Göran Wahlund, Yafeng Xue, Jonas Boström, Alleyn T. Plowright, Bengt Ohlsson, Leifeng Cheng, Sara Pahlén, Tomas Fex, Lars-Olof Larsson, Daniel Pettersen, Walter Lindberg, Maria Jonforsen, Emma Evertsson, Anders Thelin, David Gustafsson, Michael Karle, Constanze Hilgendorf, Peter Schell
Publikováno v:
ACS Medicinal Chemistry Letters. 5:538-543
A class of novel oral fibrinolysis inhibitors has been discovered, which are lysine mimetics containing an isoxazolone as a carboxylic acid isostere. As evidenced by X-ray crystallography the inhibitors bind to the lysine binding site in plasmin thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4ba76c0c82c7a2b79477544abceb03
https://doi.org/10.1021/ml400526d
https://doi.org/10.1021/ml400526d
Autor:
Sarah Schweeberg, Reinhold Tacke, Udo Bauer, Steffen Falgner, Steffen Dörrich, Christian Burschka, Britt Marie Wissing, Peter Schell, Peter Brodin, Babro Basta
Publikováno v:
Organometallics. 31:5903-5917
A series of seven silicon-containing dipeptides ((S,R)-5, (S,S)-5, (S,R)-6, (S,R)-7, (S,S)-7, (S,R)-8, and (S,S)-8) was prepared in multistep syntheses, starting from the enantiopure silicon-contai...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c407a650ed01a5be882562663629eb0
https://doi.org/10.1021/om300442e
https://doi.org/10.1021/om300442e
Autor:
Martina Hermann, Daniel Laxar, Christoph Krall, Christina Hafner, Oliver Herzog, Oliver Kimberger, Sebastian Koenig, Felix Kraft, Mathias Maleczek, Klaus Markstaller, Oliver Robak, Bernhard Rössler, Eva Schaden, Peter Schellongowski, Mathias Schneeweiss-Gleixner, Thomas Staudinger, Roman Ullrich, Marion Wiegele, Harald Willschke, Christian Zauner, Alexander Hermann
Publikováno v:
Annals of Intensive Care, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Background Duration of invasive mechanical ventilation (IMV) prior to extracorporeal membrane oxygenation (ECMO) affects outcome in acute respiratory distress syndrome (ARDS). In coronavirus disease 2019 (COVID-19) related ARDS, the role of
Externí odkaz:
https://doaj.org/article/1ce175bd871b40f497e0cdc4ae0e343a