Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Peter Saloupis"'
Autor:
Nomingerel Tserentsoodol, Scott W. Cousins, Peter Saloupis, Michael J. Allingham, Priyatham S Mettu
Publikováno v:
Investigative ophthalmologyvisual science. 59(8)
Purpose To determine the effects of aldosterone exposure on retinal edema and retinopathy in a mouse model of retinal vein occlusion (RVO). Methods RVO was induced immediately following intravenous injection of Rose bengal (66 mg/kg) using a 532-nm w
Autor:
Peng Hu, Diego G. Espinosa-Heidmann, Scott W. Cousins, Priyatham S Mettu, Alejandro Caicedo, Peter Saloupis, Askia K. Dunnon, Maria Grazia Spiga, Sarah Gach, Goldis Malek
PURPOSE Neovascular remodeling (NVR), the progression of small capillaries into large-caliber arterioles with perivascular fibrosis, represents a major therapeutic challenge in neovascular age-related macular degeneration (AMD). Neovascular remodelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa43d830653749c9c334dc6a9dfc9444
https://europepmc.org/articles/PMC3828044/
https://europepmc.org/articles/PMC3828044/
Autor:
Peng Hu, Mary A. Dwyer, Michael E. Boulton, Peter Saloupis, Donald P. McDonnell, Goldis Malek, Russell S. Thomas, Rolf Herrmann, Ping Yang, Amanda Bednar, Xiaoping Qi, Glenn J. Jaffe
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(43)
The aryl hydrocarbon receptor (AhR) is a nuclear receptor that regulates xenobiotic metabolism and detoxification. Herein, we report a previously undescribed role for the AhR signaling pathway as an essential defense mechanism in the pathogenesis of
Autor:
Sharon J. Elliot, Peter Saloupis, Eleut Hernandez, Michael Karl, Diego G. Espinosa-Heidmann, Scott W. Cousins, Paola Catanuto, Kenneth S. Korach, Pedro Fernandez
Epidemiological data suggest that estrogen deficiency in postmenopausal women may contribute to the severity of AMD. We discovered that 17beta-estradiol (E2) was a crucial regulator of the severity of extracellular matrix turnover (ECM) dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd4eec9b3eabb01ea630259990ed756
https://europepmc.org/articles/PMC2789169/
https://europepmc.org/articles/PMC2789169/
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 229:464-467
A condition similar to proliferative vitreoretinopathy (PVR) in man can be produced by injecting 25,000 homologous dermal fibroblasts into rabbit eyes following gas compression of the vitreous. Daunorubicin (15 nmol) was effective in preventing retin
Autor:
Goldis Malek, Donald E. Schmechel, Peter Saloupis, Dennis W. Rickman, Catherine Bowes Rickman, Patrick Sullivan, Brian E. Mace
Publikováno v:
Retinal Degenerative Diseases ISBN: 9780387284644
Age-related macular degeneration (AMD) is a late-onset, neurodegenerative disease of the retina and is the leading cause of catastrophic vision loss in the elderly. AMD usually occurs in people over the age of 65 years (Javitt et al., 2003) and accou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ab60dc54550ebb61cedbe81e8c541f
https://doi.org/10.1007/0-387-32442-9_17
https://doi.org/10.1007/0-387-32442-9_17
Autor:
Goldis, Malek, Brian, Mace, Peter, Saloupis, Donald, Schmechel, Dennis, Rickman, Patrick, Sullivan, Catherine Bowes, Rickman
Publikováno v:
Advances in experimental medicine and biology. 572
Publikováno v:
Experimental Eye Research. 60:591-593
Publikováno v:
Experimental eye research. 59(4)
Breakdown of the blood-retinal barrier occurs in inflammatory conditions and in ischemic retinal diseases such as diabetic retinopathy. Platelet-activating factor (PAF) is a potent inflammatory mediator which increases vascular permeability. The purp
Publikováno v:
Microvascular research. 47(3)
Capillary plugging by neutrophils appears to be the mechanism responsible for the no reflow phenomenon following experimental ischemia in many tissues. The purpose of this study was to determine if neutrophils plug capillaries in experimental retinal