Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Peter S. Wolf"'
Calcium Entry Blockers (CEBs) are a new class of drugs which have been pushing back the frontiers of science and medicine for almost two decades. This report reviews some of the wealth of chemical, biological and clinical data describing the discover
Publikováno v:
Journal of Cardiovascular Pharmacology. 11:538-542
The roles of vasopressin and angiotensin II in the regulation of peripheral vascular tone were investigated in control rats and in rats with chronic (15 weeks) aortic stenosis, by intravenous application of a specific antagonist to the vascular recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e53a9073dcedce13fa654651b98d6f
https://doi.org/10.1097/00005344-198805000-00005
https://doi.org/10.1097/00005344-198805000-00005
Publikováno v:
Journal of Pharmacological Methods. 15:235-243
The ability to continuously monitor the delicate balance between blood flow and oxygen consumption would be a great asset in the study of myocardial ischemia. The present study was performed, in anesthetized dogs, to validate the use of encased polar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd37e5b37d0ae302c9fd0d5d3fe817
https://doi.org/10.1016/0160-5402(86)90053-7
https://doi.org/10.1016/0160-5402(86)90053-7
Autor:
John W. Hubbard, Ronald D. Smith, Jeffrey T. Shapiro, Peter S. Wolf, Gabor Kaley, Thomas H. Hintze
Publikováno v:
Drug Development Research. 17:17-21
The cardiovascular effects of ascending doses (0.03, 0.1, 0.3, 1.0, and 3.0 mg/kg i.v.) of two angiotensin l-converting enzyme (ACE) inhibitors, REV 6207 and enalapril, were assessed in conscious furosemide-treated (3 mg/kg s.c.) monkeys. Both ACE in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9dfa022bdc0730574942256df593a8
https://doi.org/10.1002/ddr.430170103
https://doi.org/10.1002/ddr.430170103
Publikováno v:
Drug Development Research. 12:221-231
The cardiostimulatory effects of celiprolol were evaluated in isolated cat cardiac tissue to elucidate the contributions of beta versus alpha adrenoceptor mechanisms. Racemic celiprolol increased the spontaneous rate of cat right atria and the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26a19f7968bf84d62ebfd3549401f65
https://doi.org/10.1002/ddr.430120305
https://doi.org/10.1002/ddr.430120305
Autor:
Ronald D. Smith, Peter S. Wolf
Publikováno v:
Cardiovascular Drug Reviews. 2:19-35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2814cc84dc3aafcb2d640e2169823100
https://doi.org/10.1111/j.1527-3466.1984.tb00456.x
https://doi.org/10.1111/j.1527-3466.1984.tb00456.x
Publikováno v:
Drug Development Research. 9:159-169
Celiprolol is a new cardioselective beta adrenoceptor antagonist presently undergoing worldwide clinical traits. The present study was undertaken to further evaluate the beta antagonist and hemodynamic effects of celiprolol compared to the known beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217efb688259e9ba67a8d0c276236839
https://doi.org/10.1002/ddr.430090208
https://doi.org/10.1002/ddr.430090208
Autor:
Peter S Wolf, Tedd Pruss
Publikováno v:
American Heart Journal. 106:208-211
Indapamide is a new indoline antihypertensive diuretic agent whose chemical structure differs substantially from those of the thiazides. The hydrophobic indoline moiety of indapamide confers a lipid solubility to the molecule that is 5 to 80 times gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a8a51fb2eb17fda3d16136cc4f3809
https://doi.org/10.1016/0002-8703(83)90118-7
https://doi.org/10.1016/0002-8703(83)90118-7
Publikováno v:
Pharmacology. 39:1-10
Celiprolol, propranolol or saline were administered to separate groups (n = 5-6) of anesthetized dogs in which a critical stenosis was applied to the circumflex coronary artery for 90 min and then reperfused for 30 min. Test drugs were administered a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82972b18a1231be47f8a6b8addb0bed0
https://doi.org/10.1159/000138565
https://doi.org/10.1159/000138565
Publikováno v:
Pharmacology. 33:139-147
Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue. In the present study, canine coronary arterial rings were incubated with various treatments and exposed to 5HT (4 X 10(-7) M) and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f4c5ae865abb3653434bd35e3675f8
https://doi.org/10.1159/000138211
https://doi.org/10.1159/000138211