Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter S. J. Bailey"'
Autor:
Peter S. J. Bailey, Brian M. Ortmann, Anthony W. Martinelli, Jack W. Houghton, Ana S. H. Costa, Stephen P. Burr, Robin Antrobus, Christian Frezza, James A. Nathan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
2-oxoglutarate links mitochondrial metabolism to oxygen sensing, gene transcription and epigenetic modifications. Here, the authors describe a mutagenesis screen to find genes that control 2-oxoglutarate levels, and identify ABHD11 as a mitochondrial
Externí odkaz:
https://doaj.org/article/368ff8225df849cf9afb4ff9c4c9c5e7
Autor:
Peter S. J. Bailey, James A. Nathan
Publikováno v:
Biomedicines, Vol 6, Iss 2, p 60 (2018)
Hypoxia-inducible transcription factors (HIFs) facilitate cellular adaptations to low-oxygen environments. However, it is increasingly recognised that HIFs may be activated in response to metabolic stimuli, even when oxygen is present. Understanding
Externí odkaz:
https://doaj.org/article/9236704046ae48b5a13d9a0687e5aa0d
Autor:
James A. Nathan, Patrick H. Maxwell, Rachel Seear, David R. Mole, Ana Peñalver, Brian Ortmann, Peter S. J. Bailey, Peter J. Ratcliffe, Ian T Lobb, Natalie Burrows, Louise Rayner, Niek Wit
Hypoxia-inducible transcription factors (HIFs) are fundamental to the cellular adaptation to low oxygen levels but how they interact with chromatin and efficiently activate their target genes is unclear. Using genome-wide mutagenesis in human cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d8968a469c2a75191cc8e11c5346356
https://doi.org/10.21203/rs.3.rs-85295/v1
https://doi.org/10.21203/rs.3.rs-85295/v1
Autor:
Ana Peñalver, James McCaffrey, Patrick H. Maxwell, James A. Nathan, Louise H Jordon, Natalie Burrows, Niek Wit, Olivia Lombardi, Rachel Seear, Ian T Lobb, David R. Mole, Brian Ortmann, Peter S. J. Bailey, Peter J. Ratcliffe, Esther Arnaiz
Publikováno v:
Nature genetics
Hypoxia-inducible transcription factors (HIFs) are fundamental to the cellular adaptation to low oxygen levels but it is unclear how they interact with chromatin and activate their target genes. Here we use genome-wide mutagenesis to identify genes i
Autor:
James A. Nathan, Peter S. J. Bailey
Publikováno v:
Biomedicines, Vol 6, Iss 2, p 60 (2018)
Biomedicines
Biomedicines
Hypoxia-inducible transcription factors (HIFs) facilitate cellular adaptations to low-oxygen environments. However, it is increasingly recognised that HIFs may be activated in response to metabolic stimuli, even when oxygen is present. Understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d67c12519db6ff422d14eb1a4f20763
Autor:
Alexander J. Kastaniotis, J. Kalervo Hiltunen, Peter S. J. Bailey, James A. Nathan, Carol L. Dieckmann
Paredes et al. (1) describe polymerase-δ interacting protein 2 (Poldip2) as a novel regulator of mitochondrial lipoylation through stabilization of Ac-CoA synthetase medium-chain family member 1 (ACSM1). We have several concerns with their proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f1de86a40c7d94022a12a0d67244a6
https://www.repository.cam.ac.uk/handle/1810/284192
https://www.repository.cam.ac.uk/handle/1810/284192
Autor:
Christopher L.-H. Huang, James A. Fraser, Peter S. J. Bailey, Julian L. Griffin, Juliet A. Usher-Smith
Publikováno v:
The Journal of Physiology. 573:799-818
The combined effects of intracellular lactate and proton accumulation on cell volume, Vc, were investigated in resting Rana temporaria striated muscle fibres. Intracellular lactate and H+ concentrations were simultaneously increased by exposing resti