Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter S. Cheslock"'
Autor:
Colby A. Souders, Sharon E. Maynard, Jing Yan, Yang Wang, Naomi K. Boatright, Jessica Sedan, David Balyozian, Peter S. Cheslock, Deborah C. Molrine, Tiffany A. Moore Simas
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 12436-12453 (2015)
Angiogenic biomarkers, including soluble fms-like tyrosine kinase 1 (sFlt1), are thought to be predictors of preeclampsia onset; however, improvement is needed before a widespread diagnostic test can be utilized. Here we describe the development and
Externí odkaz:
https://doaj.org/article/b77505af11564f68b4ef8ae034db0f96
Autor:
Trevor J Morin, Teresa J Broering, Brett A Leav, Barbra M Blair, Kirk J Rowley, Elisabeth N Boucher, Yang Wang, Peter S Cheslock, Michael Knauber, David B Olsen, Steve W Ludmerer, Gyongyi Szabo, Robert W Finberg, Robert H Purcell, Robert E Lanford, Donna M Ambrosino, Deborah C Molrine, Gregory J Babcock
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002895 (2012)
Hepatitis C virus (HCV) infection is a leading cause of liver transplantation and there is an urgent need to develop therapies to reduce rates of HCV infection of transplanted livers. Approved therapeutics for HCV are poorly tolerated and are of limi
Externí odkaz:
https://doaj.org/article/8744314b7609471e91dbe560c056d0b8
Autor:
Nithya J Gogtay, Prasad S. Kulkarni, Peter S. Cheslock, Rajeev M. Dhere, Varsha Parulekar, B J Mahendra, D H Ashwath Narayana, B R Harish, William C. Blackwelder, Deborah C. Molrine, Renuka Munshi, Dipti Kumbhar, Sambhaji Shankar Pisal, Sunil Karande, Saket J. Thaker, Vikas D. Kshirsagar, Bhagwat Gunale, H S Ravish, Siddharth P Deshpande, Susan M. Moore
Publikováno v:
Clinical Infectious Diseases. 66:387-395
Background Lack of access to rabies immunoglobulin (RIG) contributes to high rabies mortality. A recombinant human monoclonal antibody (SII RMAb) was tested in a postexposure prophylaxis (PEP) regimen in comparison with a human RIG (HRIG)-containing
Autor:
William D. Thomas, Brett Leav, Yang Wang, Susan Sloan, Kirk J. Rowley, Peter S. Cheslock, Leila M. Sevigny, Kerry A. Garrity, Brian J. Booth, Gregory J. Babcock
Publikováno v:
Infection and Immunity. 81:3992-4000
Diphtheria antitoxin (DAT) has been the cornerstone of the treatment of Corynebacterium diphtheriae infection for more than 100 years. Although the global incidence of diphtheria has declined steadily over the last quarter of the 20th century, the di
Autor:
R.T. Chung, W.C. Chapman, Michael P. Curry, Heidi L. Smith, Elisabeth N. Boucher, Peter S. Cheslock, P.S. Mantry, Thomas D. Schiano, Deborah C. Molrine, Yang Wang
Publikováno v:
Journal of viral hepatitis. 24(3)
Summary Patients with active hepatitis C virus (HCV) infection at transplantation experience rapid allograft infection, increased risk of graft failure and accelerated fibrosis. MBL-HCV1, a neutralizing human monoclonal antibody (mAb) targeting the H
Publikováno v:
Virulence. 7(6)
Prompt administration of anti-toxin reduces mortality following Corynebacterium diphtheriae infection. Current treatment relies upon equine diphtheria anti-toxin (DAT), with a 10% risk of serum sickness and rarely anaphylaxis. The global DAT supply i
Publikováno v:
Open Forum Infectious Diseases
Background. Morbidity and mortality from toxigenic Corynebacterium diphtheriae is greatly reduced by prompt administration of anti-toxin. Current treatment relies upon equine-derived antibodies to diphtheria toxin (Diphtheria Anti-Toxin [DAT]) that c
Autor:
Peter S. Cheslock, Naomi K. Boatright, Colby A. Souders, Deborah C. Molrine, Yang Wang, Tiffany A. Moore Simas, Sharon Maynard, David Balyozian, Jessica Sedan, Jing Yan
Publikováno v:
International Journal of Molecular Sciences
Volume 16
Issue 6
Pages 12436-12453
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 12436-12453 (2015)
Volume 16
Issue 6
Pages 12436-12453
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 12436-12453 (2015)
Angiogenic biomarkers, including soluble fms-like tyrosine kinase 1 (sFlt1), are thought to be predictors of preeclampsia onset
however, improvement is needed before a widespread diagnostic test can be utilized. Here we describe the development
however, improvement is needed before a widespread diagnostic test can be utilized. Here we describe the development
Publikováno v:
Nature Genetics. 37:756-760
Errors in meiotic chromosome segregation are the leading cause of spontaneous abortions and birth defects1. In humans, chromosomes that fail to experience crossovers (or exchanges) are error-prone, more likely than exchange chromosomes to mis-segrega
Publikováno v:
Journal of Biological Chemistry. 278:48590-48601
Chromatin, a combination of nucleosomes and linker histones, inhibits transcription by blocking polymerase movement and access of factors to DNA. ATP-dependent remodeling complexes such as SWI/SNF and RSC alter chromatin structure to increase or decr