Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Peter S. Chan"'
Autor:
Peter S. Chang, Yi-Chun Chen, Wei-Kai Hua, Jeff C. Hsu, Jui-Cheng Tsai, Yi-Wun Huang, Yi-Hsin Kao, Pei-Hua Wu, Po-Nan Wang, Yi-Fang Chang, Ming-Chih Chang, Yu-Cheng Chang, Shiou-Ling Jian, Jiann-Shiun Lai, Ming-Tain Lai, Wei-Cheng Yang, Chia-Ning Shen, Kuo-Lan Karen Wen, Sareina Chiung-Yuan Wu
Publikováno v:
PLoS ONE, Vol 19, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/a24dce73854148dc9828f7489ea2bfaa
Autor:
John M. Apostolakos, M.D., M.P.H., Toufic R. Jildeh, M.D., Rony-Orijit Dey Hazra, M.D., Maria E. Dey Hazra, M.D., Peter S. Chang, M.D., Annabel R. Geissbuhler, B.S., Joan C. Rutledge, B.S., Peter J. Millett, M.D., M.Sc.
Publikováno v:
Arthroscopy Techniques, Vol 12, Iss 8, Pp e1281-e1288 (2023)
Clinical instability of the sternoclavicular (SC) joint is a challenging problem. Recurrent subluxation and pain can lead to significant functional limitations. Although many patients respond positively to conservative treatment, chronic dislocations
Externí odkaz:
https://doaj.org/article/de17f34262324b6bba29f623d4812db5
Autor:
Iryna Ivasyk, Abhinaba Chatterjee, Catherine Jordan, Matthew T. Geiselmann, Peter S. Chang, Hooman Kamel, Sariah Khormaee
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background Pediatric spinal fusion may be associated with significant intraoperative blood loss, leading to complications from transfusion, hypoperfusion and coagulopathy. One emerging strategy to mediate these risks is by utilization of the
Externí odkaz:
https://doaj.org/article/4d6d8d40b0da4dd4a2127b1167ebbda4
Autor:
George Theodore Grosu, Xun Ru, Joseph Coupet, Peter S. Chan, Fuk Wah Sum, Trina Saunders, J.Donald Albright, Marvin F Reich, Xumei Du, Efren Guillermo Delos Santos, Hossein Mazandarani, John P. Dusza
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2195-2198
Novel tricyclic benzazepine derivatives were synthesized as arginine vasopressin (AVP) antagonists. Several tricyclic compounds showed potent antagonistic activity in rat AVP receptors V 1a and V 2 . Derivatives containing pyrrolo-tricyclic amines, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1d45c3c77d723f2903fa078e46bae6
https://doi.org/10.1016/s0960-894x(03)00388-3
https://doi.org/10.1016/s0960-894x(03)00388-3
Autor:
George Theodore Grosu, Xun Ru, Trina Saunders, Joseph Coupet, Hossein Mazandarani, Venkatesan Aranapakam, Peter S. Chan, J.Donald Albright
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:1733-1736
Synthesis and structure-activity relationships (SAR) of arginine vasopressin receptor (AVP) antagonists are described. Potent and orally active compounds are prepared when tricyclic 10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine moiety in VPA-985
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc179e3e61f4572874d976c946756d74
https://doi.org/10.1016/s0960-894x(99)00278-4
https://doi.org/10.1016/s0960-894x(99)00278-4
Autor:
J. Donald Albright, Peter S. Chan
Publikováno v:
Current Pharmaceutical Design. 3:615-632
Abstract: Arginine. vasopressin (AVP) (antidiuretic harmone) exerts its action through three membrane-bound G-protein-coupled receptor subtypes (VI a, renal V2, and V3). The vasopressin-induced antidiuresis (via V2 receptors coupled to aquaporins) he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e12631985b574acb23f7a695bd48ef
https://doi.org/10.2174/138161280306221010121052
https://doi.org/10.2174/138161280306221010121052
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1819-1824
4(3H)-quinazolinones with a variety of heterocyclic substituents bound to the 6-position have been synthesized and evaluated as angiotensin II receptor antagonists both in vitro and in vivo. Some of these compounds have been shown to be potent, long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47e7ee4f23fd946fda95100e7fef8c0a
https://doi.org/10.1016/s0960-894x(01)80377-2
https://doi.org/10.1016/s0960-894x(01)80377-2
Autor:
Fong Lai, G. Vice, T. K. Bailey, Jeremy Ian Levin, A. Cobuzzi, L. Thibault, Joseph Coupet, A.M. Venkatesan, Peter S. Chan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1703-1708
The synthesis and biological evaluation of a series of 4(3H)-quinazolinones substituted at the 6-position with isoxazolines and isoxazolidines is described. Of these, compound 25a was found to be an especially potent, orally active, non-competitive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b5142af6160b9d54f3dff7e779b100
https://doi.org/10.1016/s0960-894x(00)80365-0
https://doi.org/10.1016/s0960-894x(00)80365-0
Autor:
A. Cobuzzi, Jeremy Ian Levin, G. Vice, L. Thibault, A.M. Venkatesan, Fong Lai, Peter S. Chan, T. K. Bailey, Noel Mellish, Joseph Coupet
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1709-1714
An alternative synthesis of CL332,877, a potent isoxazolidinyl-quinazolinone angiotensin II receptor antagonist, is described. In addition, the enantiomers of CL332,877 were separated and evaluated both in vitro and in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90095b7fd813a3d84997c77d6215924
https://doi.org/10.1016/s0960-894x(00)80366-2
https://doi.org/10.1016/s0960-894x(00)80366-2
Autor:
Jeremy Ian Levin, J.S. Baker, G. Vice, Joseph Coupet, Andrew S. Katocs, T. K. Bailey, F.M. Lai, Gerardo D. Francisco, Peter S. Chan, A.M. Venkatesan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1135-1140
The synthesis and biological evaluation of a series of 2,3,6-substituted 4(3H)quinazolinones is described. One of these compounds, CL329, 167, was found to be a potent, orally active, competitive angiotensin II receptor antagonist with a long duratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9945a8a86472a021802cfb80a94e739c
https://doi.org/10.1016/s0960-894x(01)80243-2
https://doi.org/10.1016/s0960-894x(01)80243-2