Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter S. Carlton"'
Publikováno v:
Molecular Carcinogenesis. 47:458-465
Human studies suggest that excessive energy intake and obesity may influence prostate cancer progression. Rodent experiments demonstrate that diet restriction attenuates tumor growth in parallel with reduced vascular density. The present study examin
Autor:
Robeena M. Aziz, Mark A. Morse, Kapila A. Rodrigo, Gary D. Stoner, Peter S. Carlton, Keith Harris, Ron Nines, Ashok Kumar Gupta, Tamaro S. Hudson
Publikováno v:
Pharmaceutical Biology. 40:43-49
Previous studies in our laboratory have demonstrated the inhibitory effects of freeze-dried strawberries and black raspberries on N-nitrosomethylbenzylamine (NMBA)-induced tumorigenesis in the rat esophagus. In addition, organic extracts from strawbe
Autor:
Ashok Gupta, Kapila A. Rodrigo, Ron Nines, Gary D. Stoner, Mark A. Morse, Robeena A. Aziz, Peter S. Carlton, Deborah L. Gray, Vernon E. Steele
Publikováno v:
JNCI Journal of the National Cancer Institute. 93:990-998
Background: 9-cis-Retinoic acid (9-cis-RA) and N-(4hydroxyphenyl)retinamide (4-HPR) are effective chemopreventive agents against epithelial tumors in the oral cavity, breast, and prostate. We tested the inhibitory activity of these retinoids against
Publikováno v:
Cancer Letters. 162:19-26
Previous studies in our laboratory have shown that 6-phenylhexyl isothiocyanate (PHITC), enhances N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats while the shorter chain analogs, phenylethyl isothiocyanate (PEITC), and
Publikováno v:
Cancer Letters. 159:113-117
In the present study, we examined the ability of lyophilized strawberries in the diet to inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)- and benzo[a]pyrene (B[a]P)-induced lung tumorigenesis in the A/J mouse. Groups of 20 mice were admi
Autor:
Haiyan Qin, Miranda E. Rose, Robeena M. Aziz, Rakesh Dixit, Peter S. Carlton, Gary D. Stoner, Tong Chen
Publikováno v:
Carcinogenesis. 26(9)
Epidemiological studies suggest that the frequent intake of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a decreased risk of developing esophageal squamous cell carcinoma (SCC). This decrease is thought to correlate with the inhi
Autor:
Beth W, Liston, Ronald, Nines, Peter S, Carlton, Ashok, Gupta, Robeena, Aziz, Wendy, Frankel, Gary D, Stoner
Publikováno v:
Cancer research. 63(10)
Perillyl alcohol (POH) is a monoterpene found in lavender, spearmint, and cherries. Phase I clinical trials with this agent have shown a favorable toxicity profile and preliminary data indicate some chemotherapeutic efficacy in advanced cancers. Anim
Publikováno v:
Journal of toxicology and environmental health. Part A. 65(15)
Previous in vitro studies demonstrated that the rat esophageal carcinogen N-nitrosomethylbenzylamine (NMBA) is metabolically activated by cytochrome P-450s (CYP) 2A3 and 2E1. However, the in vivo role of these P-450s in the metabolism of NMBA has not
Autor:
Peter S, Carlton, Rajaram, Gopalakrishnan, Ashok, Gupta, Beth W, Liston, Suzy, Habib, Mark A, Morse, Gary D, Stoner
Publikováno v:
Cancer research. 62(15)
Epidemiological studies indicate an association between the frequent use of nonsteroidal anti-inflammatory drugs and decreased risk for esophageal cancer. These studies suggest that limiting excess prostaglandin production, via inhibition of cyclooxy
Autor:
Gabriel K. Harris, Ronald Nines, Beth W. Liston, Laura A. Kresty, Gary D. Stoner, Ashok Gupta, Peter S. Carlton
Publikováno v:
Molecular carcinogenesis. 32(1)
N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis is an important model for squamous cell carcinoma of the human esophagus. In this model, previous studies have shown that the GGA-->GAA Ha-ras codon 12 mutation is present in the