Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Peter S Tobias"'
Autor:
Young Jun Kang, Motoyuki Otsuka, Arjen van den Berg, Lixin Hong, Zhe Huang, Xiurong Wu, Duan-Wu Zhang, Bruce A Vallance, Peter S Tobias, Jiahuai Han
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000934 (2010)
Intestinal epithelial cells (IECs) compose the first barrier against microorganisms in the gastrointestinal tract. Although the NF-kappaB pathway in IECs was recently shown to be essential for epithelial integrity and intestinal immune homeostasis, t
Externí odkaz:
https://doaj.org/article/490526f1daf74d059290c0f4080e0328
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 10, Pp 2126-2132 (2012)
Atherosclerosis is a chronic inflammatory vascular disease. Toll-like receptors (TLRs) are major initiators of inflammation. TLR2 promotes atherosclerosis in LDL receptor (LDLr)-deficient mice fed a high-fat diet (HFD). TLR2 forms heterodimers with T
Autor:
Grant D. Barish, Ira Tabas, Peter S. Tobias, Audrey S. Black, Connie W.H. Woo, Linda K. Curtiss, M. Rachel Richards, David J. Bonnet
Publikováno v:
Innate Immunity. 19:20-29
Signaling through MyD88, an adaptor utilized by all TLRs except TLR3, is pro-atherogenic; however, it is unknown whether signaling through TIR-domain-containing adaptor-inducing interferon-β (TRIF), an adaptor used only by TLRs 3 and 4, is relevant
Autor:
Peter S. Tobias, Alaa M Afify, Sridevi Devaraj, Rajendra Ramsamooj, Balakuntalam S. Kasinath, Ishwarlal Jialal
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:1796-1804
Objective— Type 1 diabetes (T1DM) is a proinflammatory state and confers an increased risk for vascular complications. Toll-like receptors (TLR) could participate in diabetic vasculopathies. Whether TLR activation contributes to the proinflammatory
Autor:
Linda K. Curtiss, Peter S. Tobias
Publikováno v:
Journal of Lipid Research, Vol 50, Iss, Pp S340-S345 (2009)
Atherosclerosis is inflammation of the vessel wall of the arterial tree. This inflammation arises at specific areas that experience disturbed blood flow such as bifurcations and the lesser curvature of the aortic arch. Although all endothelial cells
Autor:
Linda K. Curtiss, Peter S. Tobias
Publikováno v:
Seminars in Immunopathology. 30:23-27
Atherosclerosis was once thought to be solely a disease of lipid accumulation in the vessel wall. It does involve lipid accumulation, but inflammation appears to be an important driving factor. Consequently, our laboratory undertook to examine the ro
Publikováno v:
Lankesteriana: International Journal on Orchidology; 2007: Lankesteriana: Volumen 7, Número 1-2
Portal de Revistas UCR
Universidad de Costa Rica
instacron:UCR
Portal de Revistas UCR
Universidad de Costa Rica
instacron:UCR
Almost every orchid society and orchid grower realizes that orchids in the wild are in danger of dis- appearing. The simple growth of the human popula- tion dictates that spaces that once were subject only to the vagaries of nature are now impacted b
Publikováno v:
Immunologic Research. 34:193-210
The identification of Toll-like receptors (TLRs) as key patternrecognition receptors of innate immunity has opened inquiries into previously unknown disease mechanisms. The ability of TLRs to detect a spectrum of pathogen-derived molecules defines th