Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peter S Back"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011707 (2023)
The inner membrane complex (IMC) of Toxoplasma gondii is essential for all phases of the parasite's life cycle. One of its most critical roles is to act as a scaffold for the assembly of daughter buds during replication by endodyogeny. While many dau
Externí odkaz:
https://doaj.org/article/380e8c347a2944668f3873a8e132e05c
Autor:
Peter S. Back, William J. O’Shaughnessy, Andy S. Moon, Pravin S. Dewangan, Michael L. Reese, Peter J. Bradley
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The Toxoplasma inner membrane complex (IMC) is a specialized organelle that is crucial for the parasite to establish an intracellular lifestyle and ultimately cause disease. The IMC is composed of both membrane and cytoskeletal components, f
Externí odkaz:
https://doaj.org/article/6ace665ad77e43e0bad408102cc5b61c
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The IMC is an important organelle that apicomplexan parasites use to maintain their intracellular lifestyle. While many IMC proteins have been identified, only a few central players that are essential for internal budding have been described and even
Externí odkaz:
https://doaj.org/article/82149a155c5143a0bb944984b336794c
Autor:
Peter S. Back, Andy S. Moon, Rebecca R. Pasquarelli, Hannah N. Bell, Juan A. Torres, Allan L. Chen, Jihui Sha, Ajay A. Vashisht, James A. Wohlschlegel, Peter J. Bradley
Publikováno v:
mBio. 14
The inner membrane complex (IMC) is a conserved structure across the Apicomplexa phylum, which includes obligate intracellular parasites that cause toxoplasmosis, malaria, and cryptosporidiosis. The IMC is critical for the parasite to maintain its in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f479a0410ff0d508b5267ede7952d323
https://doi.org/10.1128/mbio.03042-22
https://doi.org/10.1128/mbio.03042-22
Autor:
Rodolpho Ornitz Oliveira Souza, Kylie N. Jacobs, Peter S. Back, Peter J. Bradley, Gustavo Arrizabalaga
Publikováno v:
Journal of Cell Science. 135
The single mitochondrion of Toxoplasma gondii is highly dynamic, being predominantly in a peripherally distributed lasso-shape in intracellular parasites and collapsed in extracellular parasites. The peripheral positioning of the mitochondrion is ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5e46eebe190dad4f206c3f4983de95
https://doi.org/10.1242/jcs.260083
https://doi.org/10.1242/jcs.260083
Autor:
Peter S. Back, William J. O’Shaughnessy, Andy S. Moon, Pravin S. Dewangan, Xiaoyu Hu, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley, Michael L. Reese
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 22
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 22
Significance Apicomplexan parasites include organisms that cause widespread and devastating human diseases such as malaria, cryptosporidiosis, and toxoplasmosis. These parasites are named for a structure, called the “apical complex,” that organiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593a4f59b04520baa9527f988144e881
Autor:
Charles Choi, Peter S. Back, Peter J. Bradley, Yasaman Jami-Alahmadi, James A. Wohlschlegel, Ajay A. Vashisht, Andy S. Moon
Publikováno v:
PLoS Biology
PLoS Biology, Vol 17, Iss 10, p e3000475 (2019)
PLoS Biology, Vol 17, Iss 10, p e3000475 (2019)
The Toxoplasma gondii inner membrane complex (IMC) is an important organelle involved in parasite motility and replication. The IMC resides beneath the parasite’s plasma membrane and is composed of both membrane and cytoskeletal components. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258f2ced97dc85d5526f4c92afcf00e2
https://pubmed.ncbi.nlm.nih.gov/31584943
https://pubmed.ncbi.nlm.nih.gov/31584943
Autor:
Alfred L Yergey, Paul S Blank, Stephanie M Cologna, Peter S Backlund, Forbes D Porter, Allan J Darling
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192424 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0175478.].
Externí odkaz:
https://doaj.org/article/77a7f9e9b406453d9b51ce74467b120d
Autor:
Alfred L Yergey, Paul S Blank, Stephanie M Cologna, Peter S Backlund, Forbes D Porter, Allan J Darling
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175478 (2017)
2-Hydroxypropyl-beta-cyclodextrin (HPβCD) has gained recent attention as a potential therapeutic intervention in the treatment of the rare autosomal-recessive, neurodegenerative lysosomal storage disorder Niemann-Pick Disease Type C1 (NPC1). Notably
Externí odkaz:
https://doaj.org/article/309bd46d7fc64edc9f4871f94f9ecd95
Autor:
Stephanie M J Fliedner, Nina Kaludercic, Xiao-Sheng Jiang, Hana Hansikova, Zuzana Hajkova, Jana Sladkova, Andrea Limpuangthip, Peter S Backlund, Robert Wesley, Lucia Martiniova, Ivana Jochmanova, Nikoletta K Lendvai, Jan Breza, Alfred L Yergey, Nazareno Paolocci, Arthur S Tischler, Jiri Zeman, Forbes D Porter, Hendrik Lehnert, Karel Pacak
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40949 (2012)
A glycolytic profile unifies a group of pheochromocytomas and paragangliomas (PHEOs/PGLs) with distinct underlying gene defects, including von Hippel-Lindau (VHL) and succinate dehydrogenase B (SDHB) mutations. Nevertheless, their tumor aggressivenes
Externí odkaz:
https://doaj.org/article/844067b0e35e427194db189b9be25cdb