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pro vyhledávání: '"Peter Rozik"'
Autor:
Josephine Davey-Young, Farah Hasan, Rasangi Tennakoon, Peter Rozik, Henry Moore, Peter Hall, Ecaterina Cozma, Julie Genereaux, Kyle S. Hoffman, Patricia P. Chan, Todd M. Lowe, Christopher J. Brandl, Patrick O’Donoghue
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-23 (2024)
ABSTRACTTranslation fidelity relies on accurate aminoacylation of transfer RNAs (tRNAs) by aminoacyl-tRNA synthetases (AARSs). AARSs specific for alanine (Ala), leucine (Leu), serine, and pyrrolysine do not recognize the anticodon bases. Single nucle
Externí odkaz:
https://doaj.org/article/b5dfad6187bd4976a2eaefb2e55ed373
Autor:
Tarana Siddika, Nileeka Balasuriya, Mallory I. Frederick, Peter Rozik, Ilka U. Heinemann, Patrick O’Donoghue
Publikováno v:
Cells, Vol 11, Iss 23, p 3834 (2022)
Protein kinase B (AKT1) is a serine/threonine kinase and central transducer of cell survival pathways. Typical approaches to study AKT1 biology in cells rely on growth factor or insulin stimulation that activates AKT1 via phosphorylation at two key r
Externí odkaz:
https://doaj.org/article/c298f968b214421fa1429d174d9c4f93
Autor:
Peter Rozik, Robert Szabla, Jeremy T. Lant, Rashmi Kiri, David E. Wright, Murray Junop, Patrick O’Donoghue
Publikováno v:
RNA Biology. 19:220-232
High-fidelity translation was considered a requirement for living cells. The frozen accident theory suggested that any deviation from the standard genetic code should result in the production of so much mis-made and non-functional proteins that cells