Výsledky vyhledávání - "Peter Romeis"

1,25-Dihydroxyvitamin D3-glycoside of herbal origin exhibits delayed release pharmacokinetics when compared to its synthetic counterpart

Autor: Phoukham Phothirath, Heinrich Bachmann, Marie-Noëlle Horcajada, Peter Romeis, Elizabeth Offord-Cavin, Georg A. Mathis

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 136:333-336

Vitamin D requires two metabolic steps to become biologically active. In a first step 25-hydroxyvitamin D3 is formed, which acts as storage form. After a tightly controlled step in kidney the active metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308a7036467a54af11c91995acf24e5d
https://doi.org/10.1016/j.jsbmb.2012.09.016

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Autor: Thomas Nolte, Thomas Klenner, Rosario Lizio, Degenhard Marx, Gerrit Borchard, Wolfgang Jahn, Peter Romeis, Antonio W Sarlikiotis, Claus-Michael Lehr

Publikováno v: Pharmaceutical Research. 18:771-779

Purpose. To study the pulmonary absorption and tolerability of various formulations of the decapeptide cetrorelix acetate in rats by a new aerosol delivery system (ASTA-ADS) for intratracheal application.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::365dbbbc994e7bfaea806a03677cabe6
https://doi.org/10.1023/a:1011028227155

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Quantitative analysis of D-24851, a novel anticancer agent, in human plasma and urine by liquid chromatography coupled with tandem mass spectrometry

Autor: E. Stokvis, Mariët Ouwehand, Jan H.M. Schellens, Yvonne Schnaars, Peter Romeis, Matthijs M. Tibben, Martina Grigat, Jos H. Beijnen, Lianda G. A. H. Nan-Offeringa, Hilde Rosing

Publikováno v: Rapid communications in mass spectrometry : RCM. 18(13)

The development of a liquid chromatography/tandem mass spectrometric assay for the quantitative analysis of the novel tubulin inhibitor D-24851 in human plasma and urine is described. D-24851 and the deuterated internal standard were extracted from 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a51d7019ad345d25dd7c8ac0d5b5023
https://pubmed.ncbi.nlm.nih.gov/15216507

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Crossover randomized comparison of intravenous versus intravenous/oral mesna in soft tissue sarcoma treated with high-dose ifosfamide

Autor: Joseph R, Mace, Mary L, Keohan, Heinz, Bernardy, Klaus, Junge, Georg, Niebch, Peter, Romeis, Aangelika, Thoma, Thomas, Wagner, Udo, Mueller, George, Demetri, Laurence H, Baker

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(16 Pt 1)

We conducted our study to determine the pharmacokinetics (PK) and clinical efficacy of oral mesna in patients receiving ifosfamide for soft tissue sarcoma.Seventeen patients were enrolled in a randomized prospective Phase I/II study. Seventeen patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::463674ed687abee6a3d080782573e7ca
https://pubmed.ncbi.nlm.nih.gov/14676103

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Pharmacokinetic-pharmacodynamic modeling of testosterone and luteinizing hormone suppression by cetrorelix in healthy volunteers

Autor: Peter Romeis, Hartmut Derendorf, Birgit Pechstein, Mathias Locher, Robert Hermann, Nelamangala V. Nagaraja

Publikováno v: Journal of clinical pharmacology. 40(3)

Cetrorelix (CET), a potent luteinizing hormone-releasing hormone (LH-RH) antagonist, was recently approved for the prevention of premature ovulation in patients undergoing a controlled ovarian stimulation (COS), followed by oocyte pickup and assisted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eae9fffed05d585f4524a4df1a7928c
https://pubmed.ncbi.nlm.nih.gov/10709155

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