Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Peter Rabinovitch"'
Autor:
Huiliang Zhang, Peter Rabinovitch
Publikováno v:
Bio-Protocol, Vol 12, Iss 10 (2022)
The isolation of intact single adult cardiomyocytes from model animals, mouse and rat, is an essential tool for cardiac molecular and cellular research. While several methods are reported for adult mouse cardiomyocyte isolation, the viability and yie
Externí odkaz:
https://doaj.org/article/e8e3e59e79174c5b83c689984997820f
Autor:
Ying Ann Chiao, Huiliang Zhang, Mariya Sweetwyne, Jeremy Whitson, Ying Sonia Ting, Nathan Basisty, Lindsay K Pino, Ellen Quarles, Ngoc-Han Nguyen, Matthew D Campbell, Tong Zhang, Matthew J Gaffrey, Gennifer Merrihew, Lu Wang, Yongping Yue, Dongsheng Duan, Henk L Granzier, Hazel H Szeto, Wei-Jun Qian, David Marcinek, Michael J MacCoss, Peter Rabinovitch
Publikováno v:
eLife, Vol 9 (2020)
Diastolic dysfunction is a prominent feature of cardiac aging in both mice and humans. We show here that 8-week treatment of old mice with the mitochondrial targeted peptide SS-31 (elamipretide) can substantially reverse this deficit. SS-31 normalize
Externí odkaz:
https://doaj.org/article/720f135c89f7440e948956a2b4dd4a5d
Autor:
Gavin Pharaoh, Varun Kamat, Sricharan Kannan, Rudolph S. Stuppard, Jeremy Whitson, Miguel Martin-Perez, Wei-Jun Qian, Michael J. MacCoss, Judit Villen, Peter Rabinovitch, Matthew D. Campbell, Ian R. Sweet, David J. Marcinek
Publikováno v:
bioRxiv
SUMMARYAging muscle experiences functional decline in part mediated by impaired mitochondrial ADP sensitivity. Elamipretide (ELAM) rapidly improves physiological and mitochondrial function in aging and binds directly to the mitochondrial ADP transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c98286de598fc2da4f8bdf9d060b0a
https://europepmc.org/articles/PMC9915686/
https://europepmc.org/articles/PMC9915686/
Autor:
Ann V. Griffith, Thomas Venables, Jianjun Shi, Andrew Farr, Holly van Remmen, Luke Szweda, Mohammad Fallahi, Peter Rabinovitch, Howard T. Petrie
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1071-1079 (2015)
T lymphocytes are essential mediators of immunity that are produced by the thymus in proportion to its size. The thymus atrophies rapidly with age, resulting in progressive diminution of new T cell production. This decreased output is compensated by
Externí odkaz:
https://doaj.org/article/dfea9ee59cf5442fba068048f8e21d91
Autor:
Randy Strong, Richard A. Miller, Catherine J. Cheng, James F. Nelson, Jonathan Gelfond, Shailaja Kesaraju Allani, Vivian Diaz, Angela Olsen Dorigatti, Jonathan Dorigatti, Elizabeth Fernandez, Andrzej Galecki, Brett Ginsburg, Karyn L. Hamilton, Martin A. Javors, Kerry Kornfeld, Matt Kaeberlein, Suja Kumar, David B. Lombard, Marisa Lopez‐Cruzan, Benjamin F. Miller, Peter Rabinovitch, Peter Reifsnyder, Nadia A. Rosenthal, Molly A. Bogue, Adam B. Salmon, Yousin Suh, Eric Verdin, Herbert Weissbach, John Newman, Francesca Maccchiarini, David E. Harrison
Publikováno v:
Aging Cell. 21
Mice bred in 2017 and entered into the C2017 cohort were tested for possible lifespan benefits of (R/S)-1,3-butanediol (BD), captopril (Capt), leucine (Leu), the Nrf2-activating botanical mixture PB125, sulindac, syringaresinol, or the combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0221e182f811a34962b045ce59ef5ff
https://doi.org/10.1111/acel.13724
https://doi.org/10.1111/acel.13724
Autor:
Gavin, Pharaoh, Jacob L, Brown, Kavithalakshmi, Sataranatarajan, Parker, Kneis, Jan, Bian, Rojina, Ranjit, Niran, Hadad, Constantin, Georgescu, Peter, Rabinovitch, Qitao, Ran, Jonathan D, Wren, Willard, Freeman, Michael, Kinter, Arlan, Richardson, Holly, Van Remmen
Publikováno v:
Scientific Reports
Defects in neuromuscular innervation contribute significantly to the age-related decline in muscle mass and function (sarcopenia). Our previous studies demonstrated that denervation induces muscle mitochondrial hydroperoxide production (H2O2 and lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::192cceb214fdacef24166b28663d0047
https://pubmed.ncbi.nlm.nih.gov/32811851
https://pubmed.ncbi.nlm.nih.gov/32811851
Publikováno v:
Computer Communications. 36:927-938
Maintaining per-flow information and state is a crucial topic in network monitoring. Tracking per-flow state is a relatively new area. Two main approaches have been proposed for tracking state: Binned Duration Flow Tracking (BDFT) and Fingerprint-Com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2953c5d3bdcdf0ca710790285eb4240d
https://doi.org/10.1016/j.comcom.2012.12.010
https://doi.org/10.1016/j.comcom.2012.12.010
Publikováno v:
International Journal of Business Data Communications and Networking. 3:60-74
We present a new approach using data-mining technique and, in particular, decision tree to classify peer-to-peer (P2P) traffic in IP networks. We captured the Internet traffic at a main gateway router, performed preprocessing on the data, selected th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5819653c06178c317bddcd826137b2c
https://doi.org/10.4018/jbdcn.2007100104
https://doi.org/10.4018/jbdcn.2007100104