Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Peter R.W. Gowler"'
Autor:
Amanda Lillywhite, Stephen G. Woodhams, Sara V. Gonçalves, David J.G. Watson, Li Li, James J. Burston, Peter R.W. Gowler, Meritxell Canals, David A. Walsh, Gareth J. Hathway, Victoria Chapman
Publikováno v:
PAIN Reports, Vol 6, Iss 4, p e956 (2021)
Abstract. Introduction:. Negative affect, including anxiety and depression, is prevalent in chronic pain states such as osteoarthritis (OA) and associated with greater use of opioid analgesics, potentially contributing to present and future opioid cr
Externí odkaz:
https://doaj.org/article/5ec1331b06bf473e8821f26c427d8514
Autor:
Lilian N. Nwosu, Peter R.W. Gowler, James J. Burston, Biljana Rizoska, Karin Tunblad, Erik Lindström, Urszula Grabowska, Li Li, Dan F. McWilliams, David A. Walsh, Victoria Chapman
Publikováno v:
PAIN Reports, Vol 3, Iss 6, p e685 (2018)
Abstract. Introduction:. The mounting evidence that osteoclasts play an important role in osteoarthritis (OA) pain lead us to investigate the effects of L-006235, a potent and selective inhibitor of cathepsin K, on pain behaviour and joint pathology
Externí odkaz:
https://doaj.org/article/4771b6815baa4660a719f82d83a56971
Autor:
Sara Gonçalves, Peter R.W. Gowler, Stephen G. Woodhams, James Turnbull, Gareth Hathway, Victoria Chapman
Publikováno v:
Neuropharmacology. 213:109075
Osteoarthritis (OA) is a chronic joint disease that represents an increasingly substantial global burden. Joint pain is the most significant symptom of OA. Unfortunately, current pharmacological treatments for OA pain are often not wholly efficacious