Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter R.B. Noel"'
Publikováno v:
Toxicology Letters. 1:17-20
Pivampicillin is the pivaloyloxymethyl ester of ampicillin, into which it is orally to groups each of 3 male and 3 female Beagles at levels of 630, 210 and 70 mg/kg body weight respectively for 14 weeks. The only clinical sign was vomiting at the 630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6501991ab3cc3e09cac7059e1f3da80
https://doi.org/10.1016/0378-4274(77)90015-7
https://doi.org/10.1016/0378-4274(77)90015-7
Publikováno v:
Toxicology and Applied Pharmacology. 10:183-198
Dogs were dosed orally once a day, 6 days per week, with isoniazid and its methanosulfonate derivative at various dosages over a period of 6 months. The principal objective was to study the chronic oral toxicity of the methanosulfonate, and the secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc07a374e2865990e99608f08bf4316
https://doi.org/10.1016/0041-008x(67)90103-2
https://doi.org/10.1016/0041-008x(67)90103-2
Autor:
Alastair N. Worden, Lionel E. Mawdesley-Thomas, Peter R.B. Noel, Maureen A. Fletcher, Anthony K. Palmer
Publikováno v:
Toxicology and applied pharmacology. 27(2)
Lenacil (Herbicide 634), 3-cyclohexyl-5,6-trimethyleneuracil, was incorporated at levels up to 10,000 ppm in the diets of rats and dogs in studies lasting 2 years. There was an almost complete absence of toxic responses in both species, with no evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984c2e98277f47858eb820c12f509e15
https://pubmed.ncbi.nlm.nih.gov/4852033
https://pubmed.ncbi.nlm.nih.gov/4852033
Autor:
Alan E. Street, Donald W. Jolly, Kenneth W.G. Shillam, Lionel E. Mawdesley-Thomas, Peter R.B. Noel, Keith C. Barnett, John S. Leahy, William C. Tucker, Peter F. Squires, Ronald E. Davies, Alastair N. Worden
Publikováno v:
Toxicology. 3(2)
Dimethyl sulphoxide (DMSO) was tested for oral toxicity in rats and dogs, and dermal toxicity in rabbits and pigs. Oral administration was by gastric intubation as a 50% equeous solution, 5 days/week at levels equivalent to 9.0, 3.0 or 1.0 ml undilut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5547b6efc88714004da6ecd582454e24
https://pubmed.ncbi.nlm.nih.gov/1124535
https://pubmed.ncbi.nlm.nih.gov/1124535
Publikováno v:
Toxicology and applied pharmacology. 23(1)
Ronnel, O,O-dimethyl-O-(2,4,5-trichlorophenyl) phosphorothioate, was subjected to a toxicity study lasting 2 yr in the dog. Throughout the period there were not any overt clinical signs that could be attributed to ronnel, and body weight did not appe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c60f2ca7425f92cfd88800ea1a45295
https://pubmed.ncbi.nlm.nih.gov/4116048
https://pubmed.ncbi.nlm.nih.gov/4116048
Publikováno v:
Toxicology and applied pharmacology. 24(3)
Gusathion or O,O -dimethyl- S (4-oxobenzotriazin-3-methyl) phosphorodithioate (guthion) was subjected to toxicity studies lasting 2 years in rats and dogs. In the rat study, a dietary concentration of 50–100 ppm gusathion (approximately 5–10 mg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bf3c7e64908a3762de5d5728663b4d
https://pubmed.ncbi.nlm.nih.gov/4704814
https://pubmed.ncbi.nlm.nih.gov/4704814
Prolonged toxicity studies with -(4-methylpiperidino)-p-fluorobutyrophenone, a new neuroleptic agent
Autor:
Peter R.B. Noel, Kenneth H. Harper
Publikováno v:
Toxicology and applied pharmacology. 19(2)
The toxicity of γ-(4-methylpiperidino)-p-fluorobutyrophenone (FG5111) was studied during its daily po administration to rats and beagle dogs over a 13-wk period. Preliminary dose ranging experiments showed fatalities and central nervous system intox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20c327c51db7fd27189b1ae3797448d
https://pubmed.ncbi.nlm.nih.gov/5570964
https://pubmed.ncbi.nlm.nih.gov/5570964