Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Peter R. Bär"'
Autor:
Peter R. Bär
Publikováno v:
European Journal of Pharmacology. 719:2-8
This text is based on three long interviews in Utrecht University′s Faculty Club, and on almost 40 years of working together in the same city, the same department, the same university.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a09e539567a34cb287d47e322f62432a
https://doi.org/10.1016/j.ejphar.2013.07.018
https://doi.org/10.1016/j.ejphar.2013.07.018
Autor:
Peter R. Bär, W.H. Gispen, Eldon E. Geisert, S. Dijkstra, Alex J. Lankhorst, Frank P.T. Hamers, Elbert A.J. Joosten, Simone E.J. Duis, I.M. Pans, H. Veldman
Publikováno v:
Experimental Neurology. 202:57-66
We previously demonstrated that the tetraspanin protein CD81 is up-regulated by astrocytes and microglia after traumatic spinal cord injury in rats and that CD81 is involved in adhesion and proliferation of cultured astrocytes and microglia. Since th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bb402530702da21459181a67cd4b8d
https://doi.org/10.1016/j.expneurol.2006.05.011
https://doi.org/10.1016/j.expneurol.2006.05.011
Publikováno v:
Neuroscience Letters. 392:22-26
To investigate the sensitivity of human Schwann cells to cisplatin (cis-DDP), different approaches to estimate DNA damage were used: the comet assay, morphological evaluation of the granular condensation of nuclear chromatin and the terminal transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b79ead1cd30fe3ba810586e683f10d
https://doi.org/10.1016/j.neulet.2005.08.068
https://doi.org/10.1016/j.neulet.2005.08.068
Publikováno v:
Neuroscience Research Communications. 35:96-104
Two cytoprotective agents, ethiofos (WR2721) and nerve growth factor (NGF), were used to diminish cisplatin-induced toxicity in Schwann cell cultures. The effect of both studied agents was estimated by a micronucleus test and the comet assay. The com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502a4724d075380538e7dd0f7b3d6ba6
https://doi.org/10.1002/nrc.20024
https://doi.org/10.1002/nrc.20024
Autor:
Klaas Nicolay, Peter R. Bär, Jeannette Hofmeijer, L. J. Kappelle, Janneke Schepers, H. B. van der Worp, Wouter B. Veldhuis
Publikováno v:
Brain Research, 1013(1), 74-82. Elsevier
We aimed to establish a rat model of space-occupying hemispheric infarction to evaluate potential treatment strategies. For adequate timing of therapy in future experiments, we studied the development of tissue damage, edema formation, and perfusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956b202afabc68a3b725afed5b3ea5af
https://doi.org/10.1016/j.brainres.2004.03.057
https://doi.org/10.1016/j.brainres.2004.03.057
Autor:
Jeannette Hofmeijer, Wouter B. Veldhuis, Klaas Nicolay, H. B. van der Worp, Peter R. Bär, Janneke Schepers, L.J. Kappelle
Publikováno v:
Stroke : a Journal of Celebral Circulation, 35(6), 1476-1481. Lippincott Williams and Wilkins Ltd.
Background and Purpose— There is no conclusive experimental support that decompressive surgery in late stages of space-occupying cerebral infarction will improve outcome. We studied the effects of delayed decompressive surgery on the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a0cef1c213fa4e4fcdb041c785d5f3
https://doi.org/10.1161/01.str.0000128415.31274.3a
https://doi.org/10.1161/01.str.0000128415.31274.3a
Autor:
H. Veldman, J. de Leeuw van Weenen, Geert Jan Groeneveld, John H. J. Wokke, Jan H. Veldink, L.H. van den Berg, F.L. van Muiswinkel, Peter R. Bär
Publikováno v:
Neuroscience Letters. 352:175-178
Transgenic mice overexpressing the human mutated form (G93A) of Cu,Zn-superoxide dismutase (mSOD1) develop motor neuron degeneration resembling amyotrophic lateral sclerosis. In vitro studies have shown that mSOD1-induced, reactive oxygen species-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4f7e206f087743a029ebf1e6156610
https://doi.org/10.1016/j.neulet.2003.08.062
https://doi.org/10.1016/j.neulet.2003.08.062
Autor:
Peter R. Bär, Liselijn A. B. Wisman, Pierre N. E. De Graan, Freek L. Van Muiswinkel, Elly M. Hol
Publikováno v:
NeuroReport. 14:1967-1970
Amyotrophic lateral sclerosis is an incurable disease in which cerebral and spinal motoneurons degenerate, causing paralysis and death within 2-5 years. One of the pathogenic factors of motoneuron death is a chronic excess of glutamate, which exceeds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1d94ac1cb5044fadb253d8abcbaafd
https://doi.org/10.1097/00001756-200310270-00017
https://doi.org/10.1097/00001756-200310270-00017
Autor:
Gerrit A. Veldink, Johannes F.G. Vliegenthart, Klaas Nicolay, Wouter B. Veldhuis, Peter R. Bär, Mauro Maccarrone, Vincenzo Di Marzo, Mario van der Stelt
Publikováno v:
Molecular Neurobiology, 26(2-3), 317-346. Humana Press
The endocannabinoid system is a valuable target for drug discovery, because it is involved in the regulation of many cellular and physiological functions. The endocannabinoid system constitutes the endogenous lipids anandamide, 2-arachidonoylglycerol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583efb68793653f23dc42c3979ffd875
https://doi.org/10.1385/mn:26:2-3:317
https://doi.org/10.1385/mn:26:2-3:317
Publikováno v:
Brain Research. 922:243-249
Chronic treatment of rat cortical slices with a relative low concentration of mitochondrial inhibitor malonate leads to cortical motoneuron (CMN) death. In the neurodegenerative disease amyotrophic lateral sclerosis (ALS) corticospinal neurons, CMNs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf3a6fd665d6bff09cd8e406fddaf35
https://doi.org/10.1016/s0006-8993(01)03178-x
https://doi.org/10.1016/s0006-8993(01)03178-x