Supplementation with fish oil and genistein, individually or in combination, protects bone against the adverse effects of methotrexate chemotherapy in rats.

Autor: Rethi Raghu Nadhanan, Jayne Skinner, Rosa Chung, Yu-Wen Su, Peter R Howe, Cory J Xian

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71592 (2013)

Cancer chemotherapy has been shown to induce long-term skeletal side effects such as osteoporosis and fractures; however, there are no preventative treatments. This study investigated the damaging effects of anti-metabolite methotrexate (MTX) subcuta

Externí odkaz: https://doaj.org/article/99f34a438aba4c6badd47b208a0d892b

A density functional study of oxygen activation by unsaturated complexes [M(bipy)(2)](2+), M = Cr and Fe

Autor: Christine J. McKenzie, John E. McGrady, Peter R. Howe

Publikováno v: Howe, P R, McGrady, J E & McKenzie, C J 2002, ' A Density Functional Study of Oxygen Activation by Unsaturated Complexes [M(bipy) 2 ] 2+, M = Cr and Fe ', Inorganic Chemistry, vol. 41, no. 8, pp. 2026-2031 . https://doi.org/10.1021/ic010782c

Density functional theory is used to probe the reaction of O(2) with the unsaturated transition-metal fragments [M(bipy)(2)](2+), M = Cr, Fe. In both cases, calculations indicate that the O(2) molecule is initially trapped as an eta(2)-bound superoxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13859568fca1e8555939bd8b9a385bf9
http://ora.ox.ac.uk/objects/uuid:e7bc79d4-a881-4495-bcc3-276db1687b23