Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter Rüthemann"'
Autor:
Alejandra Carranza Valencia, Reinhard Hirt, Doris Kampner, Andreas Hiebl, Alexander Tichy, Peter Rüthemann, Maximilian Pagitz
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 1080-1087 (2021)
Abstract Background Inhalation treatment frequently is used in dogs and cats with chronic respiratory disease. Little is known however about the performance of delivery devices and the distribution of aerosolized drugs in the lower airways. Objective
Externí odkaz:
https://doaj.org/article/56e3b04b9748473fbdd1ae96cca83b9c
Autor:
Chiara Balbo Pogliano, Marco Gatti, Peter Rüthemann, Zuzana Garajovà, Lorenza Penengo, Hanspeter Naegeli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
UV-induced mutagenic cyclobutane pyrimidine dimers on nucleosomal DNA are sensed by the damage recognition factors DDB2 and XPC via an unknown mechanism. Here, the authors show that the histone methyltransferase ASH1L regulates the DDB2 to XPC handof
Externí odkaz:
https://doaj.org/article/9d9aa0b04f364233b240cfb6b9393ea7
Autor:
Doris Kampner, Maximilian Pagitz, Alexander Tichy, Andreas Hiebl, Alejandra Carranza Valencia, Peter Rüthemann, Reinhard Hirt
Publikováno v:
Journal of Veterinary Internal Medicine, 35 (2)
Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 1080-1087 (2021)
Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 1080-1087 (2021)
Background Inhalation treatment frequently is used in dogs and cats with chronic respiratory disease. Little is known however about the performance of delivery devices and the distribution of aerosolized drugs in the lower airways. Objective To asses
Autor:
Lorenza Penengo, Chiara Balbo Pogliano, Marco Gatti, Peter Rüthemann, Hanspeter Naegeli, Zuzana Garajova
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Global-genome nucleotide excision repair (GG-NER) prevents ultraviolet (UV) light-induced skin cancer by removing mutagenic cyclobutane pyrimidine dimers (CPDs). These lesions are formed abundantly on DNA wrapped around histone octamers in nucleosome
Publikováno v:
Current Biology
Summary Background Nucleotide excision repair is a versatile DNA repair reaction that removes bulky adducts generated by environmental mutagens such as the UV spectrum of sunlight or chemical carcinogens. Current multistep models of this excision rep
Publikováno v:
The EMBO journal. 36(22)
Ultraviolet (UV) light induces mutagenic cyclobutane pyrimidine dimers (CPDs) in nucleosomal DNA that is tightly wrapped around histone octamers. How global-genome nucleotide excision repair (GG-NER) processes CPDs despite that this chromatin arrange
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
Frontiers in Genetics
Frontiers in Genetics
Global-genome nucleotide excision repair (GG-NER) prevents genome instability by excising a wide range of structurally unrelated DNA base adducts and crosslinks induced by chemical carcinogens, ultraviolet (UV) radiation or intracellular metabolic by
Autor:
Kristijan Ramadan, Peter Rüthemann, Karin Bachmann, Hanspeter Naegeli, Marjo-Riitta Puumalainen, Davor Lessel, Nina Kaczmarek
Publikováno v:
Nature Communications
Nature communications
Nature communications
DNA damage recognition subunits such as DDB2 and XPC protect the human skin from ultraviolet (UV) light-induced genome instability and cancer, as demonstrated by the devastating inherited syndrome xeroderma pigmentosum. Here we show that the benefici
Publikováno v:
Cellular and Molecular Life Sciences
The cellular defense system known as global-genome nucleotide excision repair (GG-NER) safeguards genome stability by eliminating a plethora of structurally unrelated DNA adducts inflicted by chemical carcinogens, ultraviolet (UV) radiation or endoge