Wall Shear Stress Measurement in Carotid Artery Phantoms with Variation in Degree of Stenosis Using Plane Wave Vector Doppler

Autor: Ke Yang, Peter R. Hoskins, George A. Corner, Chunming Xia, Zhihong Huang

Publikováno v: Applied Sciences, Vol 13, Iss 1, p 617 (2023)

Wall shear stress (WSS) plays an important role in the formation, growth, and rupture of atherosclerotic plaques in arteries. This study measured WSS in diseased carotid artery phantoms with degrees of stenosis varying from 0 to 60% with both steady

Externí odkaz: https://doaj.org/article/b904baf1813d4ddc988e5ed4277969ae

Low Shear Stress at Baseline Predicts Expansion and Aneurysm-Related Events in Patients With Abdominal Aortic Aneurysm

Autor: Nikhilesh Bappoo, Maaz B.J. Syed, Georgia Khinsoe, Lachlan J. Kelsey, Rachael O. Forsythe, Janet T. Powell, Peter R. Hoskins, Olivia M.B. McBride, Paul E. Norman, Shirley Jansen, David E. Newby, Barry J. Doyle

Publikováno v: Nikhilesh, B, Syed, M, Khinsoe, G, Kelsey, L J, Forsythe, R, Powell, J T, Hoskins, P R, McBride, O, Norman, P E, Jansen, S, Newby, D E & Doyle, B J 2021, ' Low shear stress at baseline predicts expansion and aneurysm-related events in patients with abdominal aortic aneurysm ', Circulation: Cardiovascular Imaging . https://doi.org/10.1161/CIRCIMAGING.121.013160

Background: Low shear stress has been implicated in abdominal aortic aneurysm (AAA) expansion and clinical events. We tested the hypothesis that low shear stress in AAA at baseline is a marker of expansion rate and future aneurysm-related events. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb615ce6d3d1336757141cb22eff5a4
https://doi.org/10.1161/circimaging.121.013160

Spatiotemporal Dynamics of Dilute Red Blood Cell Suspensions in Low-Inertia Microchannel Flow

Autor: Joana Fidalgo, Miguel O. Bernabeu, Monica Oliveira, Timm Krüger, Qi Zhou, Lavinia Calvi, Peter R. Hoskins

Publikováno v: Biophys J
Zhou, Q, Fidalgo, J, Calvi, L, Bernabeu, M O, Hoskins, P, Oliveira, M & Krüger, T 2020, ' Spatiotemporal Dynamics of Dilute Red Blood Cell Suspensions in Low-Inertia Microchannel Flow ', Biophysical Journal, vol. 118, no. 10, pp. 2561-2573 . https://doi.org/10.1016/j.bpj.2020.03.019

Microfluidic technologies are commonly used for the manipulation of red blood cell (RBC) suspensions and analyses of flow-mediated biomechanics. To enhance the performance of microfluidic devices, understanding the dynamics of the suspensions process

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af00c230a9e99fcc0b42df39a73ada02
https://doi.org/10.1016/j.bpj.2020.03.019

Wall Stress and Geometry of the Thoracic Aorta in Patients With Aortic Valve Disease

Autor: Peter R. Hoskins, Marc R. Dweck, David E. Newby, Paul Norman, Barry J. Doyle

Publikováno v: Doyle, B J, Norman, P E, Hoskins, P R, Newby, D E & Dweck, M R 2017, ' Wall Stress And Geometry Of The Thoracic Aorta In Patients With Aortic Valve Disease ', The Annals of Thoracic Surgery . https://doi.org/10.1016/j.athoracsur.2017.11.061

BACKGROUND: Aortic valve disease increases velocity and changes the way blood enters the aorta. Over time, the biomechanical environment can cause aortic remodelling. We hypothesised that aortic geometry and wall stress would be different in patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca403fe8985b03ff4cd56d194d913a6b
https://doi.org/10.1016/j.athoracsur.2017.11.061

Exploring the Biological and Mechanical Properties of Abdominal Aortic Aneurysms Using USPIO MRI and Peak Tissue Stress: A Combined Clinical and Finite Element Study

Autor: Peter R. Hoskins, Olivia M.B. McBride, Chengjia Wang, David E. Newby, Calum Gray, Scott Ian Kay Semple, Rachael O. Forsythe, L. Hollis, Jennifer M. J. Robson, Barry J. Doyle, Edwin J R van Beek, Noel Conlisk, Tom MacGillivray

Publikováno v: Journal of Cardiovascular Translational Research
Conlisk, N, Forsythe, R, Hollis, L, Doyle, B J, McBride, O, Robson, J, Wang, C, Gray, C D, Semple, S I K, MacGillivray, T, van Beek, E J R, Newby, D E & Hoskins, P R 2017, ' Exploring the Biological and Mechanical Properties of Abdominal Aortic Aneurysms Using USPIO MRI and Peak Tissue Stress : A Combined Clinical and Finite Element Study ', Journal of cardiovascular translational research . https://doi.org/10.1007/s12265-017-9766-9

Inflammation detected through the uptake of ultrasmall superparamagnetic particles of iron oxide (USPIO) on magnetic resonance imaging (MRI) and finite element (FE) modelling of tissue stress both hold potential in the assessment of abdominal aortic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcefa95011f2d0b3b9698a209126270
https://doi.org/10.1007/s12265-017-9766-9