Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Peter Passmore"'
Autor:
Xiaojian Shao, Sangeetha Vishweswaraiah, Miroslava Čuperlović-Culf, Ali Yilmaz, Celia M. T. Greenwood, Anuradha Surendra, Bernadette McGuinness, Peter Passmore, Patrick G. Kehoe, Michael E. Maddens, Steffany A. L. Bennett, Brian D. Green, Uppala Radhakrishna, Stewart F. Graham
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Post-mortem brain tissue from patients with Dementia with Lewy bodies shows differentially methylated CpG sites and potential epigenetic associations with other conditions such as mood disorders and Parkinson’s Disease.
Externí odkaz:
https://doaj.org/article/3da129927f35494b86e1e49d82421630
Autor:
Patrick G Kehoe, Nicholas Turner, Beth Howden, Lina Jarutyt, Shona L Clegg, Ian B Malone, Josephine Barnes, Casper Nielsen, Carole H Sudre, Aileen Wilson, N Jade Thai, Peter S Blair, Elizabeth J Coulthard, J Athene Lane, Peter Passmore, Jodi Taylor, Henk-Jan Mutsaerts, David L Thomas, Nick C Fox, Ian Wilkinson, Yoav Ben-Shlomo
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 8, Iss 19 (2021)
Background: Medications that modify the renin–angiotensin system may reduce Alzheimer’s disease pathology and reduce the rate of disease progression. Objective: This study investigated whether taking the antihypertensive drug losartan, in additio
Externí odkaz:
https://doaj.org/article/81e153bea7a84db597fe5cde3dbfd1f0
Autor:
Esther C. McWilliams, Florentine M. Barbey, John F. Dyer, Md Nurul Islam, Bernadette McGuinness, Brian Murphy, Hugh Nolan, Peter Passmore, Laura M. Rueda-Delgado, Alison R. Buick
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Access to affordable, objective and scalable biomarkers of brain function is needed to transform the healthcare burden of neuropsychiatric and neurodegenerative disease. Electroencephalography (EEG) recordings, both resting and in combination with ta
Externí odkaz:
https://doaj.org/article/905f8826e0a64d29bc72485fa9aab3a8
Autor:
Jeffrey Cummings, Peter Passmore, Bernadette McGuinness, Vincent Mok, Christopher Chen, Sebastiaan Engelborghs, Michael Woodward, Sagrario Manzano, Guillermo Garcia-Ribas, Stefano Cappa, Paulo Bertolucci, Leung-Wing Chu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background Mild cognitive impairment (MCI) among an aging global population is a growing challenge for healthcare providers and payers. In many cases, MCI is an ominous portent for dementia. Early and accurate diagnosis of MCI provides a win
Externí odkaz:
https://doaj.org/article/81f7739c7e8a4f77950f43d6f1f61aab
Autor:
Bannin De Witt Jansen, Kevin Brazil, Peter Passmore, Hilary Buchanan, Doreen Maxwell, Sonja J. McIlfatrick, Sharon M. Morgan, Max Watson, Carole Parsons
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Pain assessment and management in advanced and end-stage dementia are challenging; patients are at risk of under-diagnosis, under-assessment and under-treatment. Previous research has highlighted the importance of needs-driven tra
Externí odkaz:
https://doaj.org/article/135bb4c1c1fe497998d687d3af418183
Autor:
Sumeyya Akyol, Zafer Ugur, Ali Yilmaz, Ilyas Ustun, Santosh Kapil Kumar Gorti, Kyungjoon Oh, Bernadette McGuinness, Peter Passmore, Patrick G. Kehoe, Michael E. Maddens, Brian D. Green, Stewart F. Graham
Publikováno v:
Cells, Vol 10, Iss 10, p 2591 (2021)
Alzheimer’s disease (AD) is reported to be closely linked with abnormal lipid metabolism. To gain a more comprehensive understanding of what causes AD and its subsequent development, we profiled the lipidome of postmortem (PM) human brains (neocort
Externí odkaz:
https://doaj.org/article/7e97e7aa856a4300b1114c825dd147b9
Autor:
Cathal A. Cadogan, Cristín Ryan, Gerard J. Gormley, Jill J. Francis, Peter Passmore, Ngaire Kerse, Carmel M. Hughes
Publikováno v:
Pilot and Feasibility Studies, Vol 4, Iss 1, Pp 1-12 (2017)
Abstract Background A general practitioner (GP)-targeted intervention aimed at improving the prescribing of appropriate polypharmacy for older people was previously developed using a systematic, theory-based approach based on the UK Medical Research
Externí odkaz:
https://doaj.org/article/7395320a99be41a1baae3333b746fc87
Autor:
Emily Baker, Rebecca Sims, Ganna Leonenko, Aura Frizzati, Janet C Harwood, Detelina Grozeva, GERAD/PERADES, CHARGE, ADGC, EADI, IGAP consortia, Kevin Morgan, Peter Passmore, Clive Holmes, John Powell, Carol Brayne, Michael Gill, Simon Mead, Paola Bossù, Gianfranco Spalletta, Alison M Goate, Carlos Cruchaga, Wolfgang Maier, Reinhard Heun, Frank Jessen, Oliver Peters, Martin Dichgans, Lutz FröLich, Alfredo Ramirez, Lesley Jones, John Hardy, Dobril Ivanov, Matthew Hill, Peter Holmans, Nicholas D Allen, B Paul Morgan, Sudha Seshadri, Gerard D Schellenberg, Philippe Amouyel, Julie Williams, Valentina Escott-Price
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218111 (2019)
Late onset Alzheimer's disease is the most common form of dementia for which about 30 susceptibility loci have been reported. The aim of the current study is to identify novel genes associated with Alzheimer's disease using the largest up-to-date ref
Externí odkaz:
https://doaj.org/article/ba190fc9ff584d2dad1fe3c08616bffe
Autor:
Cathal A. Cadogan, Cristín Ryan, Jill J. Francis, Gerard J. Gormley, Peter Passmore, Ngaire Kerse, Carmel M. Hughes
Publikováno v:
BMC Health Services Research, Vol 16, Iss 1, Pp 1-10 (2016)
Abstract Background It is advocated that interventions to improve clinical practice should be developed using a systematic approach and intervention development methods should be reported. However, previous interventions aimed at ensuring that older
Externí odkaz:
https://doaj.org/article/1e8ee16dab8949f3a20d4297c43838eb
Autor:
Michael A. Williams, Amy J. McGowan, Chris R. Cardwell, Carol Y. Cheung, David Craig, Peter Passmore, Giuliana Silvestri, Alexander P. Maxwell, Gareth J. McKay
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 2, Pp 229-235 (2015)
Abstract Introduction Cerebral small‐vessel disease has been implicated in the development of Alzheimer's disease (AD). The retinal microvasculature enables the noninvasive visualization and evaluation of the systemic microcirculation. We evaluated
Externí odkaz:
https://doaj.org/article/0a7fdd72c1514ab98d1ee15c73fd88b5