Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Peter P. Mager"'
Autor:
Kerstin Wirkner, Patrizia Rubini, Wolfgang Nörenberg, Lars Hartmann, Peter Illes, Doreen Milius, Zoltan S. Zadori, Erzsébet Kató, Peter P. Mager, Doychin Stanchev
Publikováno v:
Journal of Neurochemistry. 107:1216-1224
The human (h) P2X(3) receptor and its mutants deficient in one out of four N-glycosylation sites were expressed in HEK293 cells. Concentration-response curves were generated by whole-cell recordings of alpha,beta-methylene ATP (alpha,beta-meATP)-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fcf6b951b5da09444b7a62f0c46f7d
https://doi.org/10.1111/j.1471-4159.2008.05655.x
https://doi.org/10.1111/j.1471-4159.2008.05655.x
Autor:
Peter P. Mager
Publikováno v:
Current Computer Aided-Drug Design. 3:248-253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a477b509df491ec323cee556df43e19
https://doi.org/10.2174/157340907782799426
https://doi.org/10.2174/157340907782799426
Autor:
Wolfgang Fischer, Helke Gröger-Arndt, Zoltán S. Zádori, Peter Illes, Kerstin Wirkner, Heike Franke, Yvonne Kullnick, Peter P. Mager
Publikováno v:
European Journal of Pharmacology. 576:7-17
Wild-type human (h) P2X(3) receptors expressed in HEK293 cells responded to the prototypic agonist alpha,beta-methylene ATP (alpha,beta-meATP) with rapidly desensitizing inward currents and an increase in the intracellular Ca(2+) concentration. In co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e473ea88b30e3eed82196f8d0ba4bd76
https://doi.org/10.1016/j.ejphar.2007.07.068
https://doi.org/10.1016/j.ejphar.2007.07.068
Publikováno v:
Letters in Drug Design & Discovery. 3:675-682
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e149335d805ce7803d8e0d169c5c3e
https://doi.org/10.2174/157018006778631929
https://doi.org/10.2174/157018006778631929
The h-P2X3 glycoprotein receptor as an example of integrating bioinformatics and structural research
Autor:
Peter Illes, Peter P. Mager
Publikováno v:
Expert Opinion on Drug Discovery. 1:303-309
This review deals with the molecular modelling of a subtype of the membrane-embedded purinoreceptor P2X family, which belongs to the large class of membrane-embedded glycoproteins. The P2X family has two transmembrane domains and a core of five extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff090e4cc40f99954b58163444007c71
https://doi.org/10.1517/17460441.1.4.303
https://doi.org/10.1517/17460441.1.4.303
Publikováno v:
Current Proteomics. 2:319-324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::873ff752c8c9d75143cdd2c6fcd6b549
https://doi.org/10.2174/157016405775201775
https://doi.org/10.2174/157016405775201775
Quantitative Structure-Activity Relationship Analysis of the Cation Permeability of the P2X2 Channel
Publikováno v:
Medicinal Chemistry. 1:109-115
The membrane-embedded, ligand-gated P2X glycoprotein receptor is a monovalent-bivalent cation channel that is activated by physiological concentrations of extracellular ATP. A quantitative structure-activity relationship (QSAR) analysis was developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd0fc6163ba14975b25f26dffad780c
https://doi.org/10.2174/1573406053175210
https://doi.org/10.2174/1573406053175210
Publikováno v:
Current Topics in Medicinal Chemistry. 4:1657-1705
Motivation: No details on P2X receptor architecture had been known at the atomic resolution level. Using comparative homology-based molecular modelling and threading, it was attempted to predict the three-dimensional structure of P2X receptors. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3863d751c290b61adc190d68c1406383
https://doi.org/10.2174/1568026043387197
https://doi.org/10.2174/1568026043387197
Autor:
Peter P. Mager, Marton B. Dobszay, Wolfgang Härtig, Yuri Zilberter, Paul Berghuis, Gunnar Schulte, Patrik Ernfors, Tibor Harkany, Tamás J. Görcs, Kyle M. Sousa
Publikováno v:
European Journal of Neuroscience. 20:1290-1306
GABAergic interneurons with high-frequency firing, fast-spiking (FS) cells, form synapses on perisomatic regions of principal cells in the neocortex and hippocampus to control the excitability of cortical networks. Brain-derived neurotrophic factor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63e3e9005a2ea21a184db998204f94e
https://doi.org/10.1111/j.1460-9568.2004.03561.x
https://doi.org/10.1111/j.1460-9568.2004.03561.x