Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Peter P, Rainer"'
Autor:
Markus Kneihsl, Thomas Gattringer, Edith Hofer, Peter P. Rainer, Gerhard Ranner, Simon Fandler-Höfler, Melanie Haidegger, Sabine Perl, Christian Enzinger, Reinhold Schmidt
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Cerebral white matter hyperintensities (WMH) have been associated with subclinical atherosclerosis including coronary artery calcification (CAC). However, previous studies on this association are limited by only cross-sectional analysis. We
Externí odkaz:
https://doaj.org/article/aee22982143f4f139fe4f48c65714d7d
Autor:
Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner-Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer, Andrew J. Boyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demo
Externí odkaz:
https://doaj.org/article/a7e2f43b7c7844a0a23cc1ccd8d00927
Autor:
Mateusz Sokolski, Sander Trenson, Justyna M. Sokolska, Domenico D'Amario, Philippe Meyer, Nana K. Poku, Tor Biering‐Sørensen, Mats C. Højbjerg Lassen, Kristoffer G. Skaarup, Eduardo Barge‐Caballero, Anne‐Catherine Pouleur, Davide Stolfo, Gianfranco Sinagra, Klemens Ablasser, Viktoria Muster, Peter P. Rainer, Markus Wallner, Alessandra Chiodini, Pascal S. Heiniger, Fran Mikulicic, Judith Schwaiger, Stephan Winnik, Huseyin A. Cakmak, Margherita Gaudenzi, Massimo Mapelli, Irene Mattavelli, Matthias Paul, Irina Cabac‐Pogorevici, Claire Bouleti, Marzia Lilliu, Chiara Minoia, Jeroen Dauw, Jérôme Costa, Ahmet Celik, Nathan Mewton, Carlos E.L. Montenegro, Yuya Matsue, Goran Loncar, Michal Marchel, Aris Bechlioulis, Lampros Michalis, Marcus Dörr, Edgard Prihadi, Felix Schoenrath, Daniel R. Messroghli, Wilfried Mullens, Lars H. Lund, Giuseppe M.C. Rosano, Piotr Ponikowski, Frank Ruschitzka, Andreas J. Flammer
Publikováno v:
ESC Heart Failure, Vol 8, Iss 6, Pp 4955-4967 (2021)
Abstract Aims We assessed the outcome of hospitalized coronavirus disease 2019 (COVID‐19) patients with heart failure (HF) compared with patients with other cardiovascular disease and/or risk factors (arterial hypertension, diabetes, or dyslipidaem
Externí odkaz:
https://doaj.org/article/e73eba554395434ea59c5c8c16953319
Publikováno v:
Metabolism Open, Vol 15, Iss , Pp 100206- (2022)
Background: The prevalence of obesity is higher in Western countries than in East Asian countries. It remains unknown whether microRNAs (miRNAs) are involved in the pathogenesis of the ethnic difference in obesity. The purpose of this study was to de
Externí odkaz:
https://doaj.org/article/8232df69b4bb4d01981276056da3f2c8
Autor:
David Zach, Klemens Ablasser, Ewald Kolesnik, Viktoria Hoeller, Friedrich Fruhwald, Florian Prüller, Clemens Reiter, Christine Beham‐Schmid, Rainer Lipp, Peter P. Rainer, Andreas Zirlik, Albert Wölfler, Nicolas Verheyen
Publikováno v:
ESC Heart Failure, Vol 8, Iss 4, Pp 3397-3402 (2021)
Abstract Amyloid light chain (AL) cardiomyopathy is the most malignant specific cardiomyopathy. According to international recommendations, it should be ruled out non‐invasively using the serum free light chain (FLC) ratio and immunofixation electr
Externí odkaz:
https://doaj.org/article/9e1d8438218b4f629a25a241ec26c276
Autor:
Florian Posch, Tobias Niedrist, Theresa Glantschnig, Saskia Firla, Florian Moik, Ewald Kolesnik, Markus Wallner, Nicolas Verheyen, Philipp J. Jost, Andreas Zirlik, Martin Pichler, Marija Balic, Peter P. Rainer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Background/PurposeThis study aims to quantify the utility of monitoring LVEF, hs-cTnT, and NT-proBNP for dynamic cardiotoxicity risk assessment in women with HER2+ early breast cancer undergoing neoadjuvant/adjuvant trastuzumab-based therapy.Material
Externí odkaz:
https://doaj.org/article/9d447758d7e1408a908b0b606cfc1778
Autor:
Elías Herrero-Galán, Inés Martínez-Martín, Cristina Sánchez-González, Natalia Vicente, Elena Bonzón-Kulichenko, Enrique Calvo, Carmen Suay-Corredera, Maria Rosaria Pricolo, Ángel Fernández-Trasancos, Diana Velázquez-Carreras, Claudio Badía Careaga, Mahmoud Abdellatif, Simon Sedej, Peter P. Rainer, David Giganti, Raúl Pérez-Jiménez, Jesús Vázquez, Jorge Alegre-Cebollada
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102306- (2022)
Titin, as the main protein responsible for the passive stiffness of the sarcomere, plays a key role in diastolic function and is a determinant factor in the etiology of heart disease. Titin stiffness depends on unfolding and folding transitions of im
Externí odkaz:
https://doaj.org/article/a20413a909e945338b56d00461d948f8
Autor:
Mark J. Ranek, Christian Oeing, Rebekah Sanchez-Hodge, Kristen M. Kokkonen-Simon, Danielle Dillard, M. Imran Aslam, Peter P. Rainer, Sumita Mishra, Brittany Dunkerly-Eyring, Ronald J. Holewinski, Cornelia Virus, Huaqun Zhang, Matthew M. Mannion, Vineet Agrawal, Virginia Hahn, Dong I. Lee, Masayuki Sasaki, Jennifer E. Van Eyk, Monte S. Willis, Richard C. Page, Jonathan C. Schisler, David A. Kass
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Carboxyl terminus of Hsc70-interacting protein (CHIP) is proteostasis regulator. Here the authors show that CHIP-mediated protein turnover is enhanced by PKG-mediated phosphorylation, which results in attenuated cardiac ischemic proteotoxicity.
Externí odkaz:
https://doaj.org/article/7e6f8490744a4cef9d24e2c03e23c499
Autor:
Johannes Schmid, Meinrad Beer, Andrea Berghold, Tatjana Stojakovic, Hubert Scharnagl, Benjamin Dieplinger, Stefan Quasthoff, Josepha S. Binder, Peter P. Rainer
Publikováno v:
ESC Heart Failure, Vol 7, Iss 4, Pp 1900-1908 (2020)
Abstract Aims Cardiac involvement in myopathies that primarily affect the skeletal muscle is variable and may be subtle, necessitating sensitive diagnostic approaches. Here, we describe the prevalence of cardiac abnormalities in a cohort of patients
Externí odkaz:
https://doaj.org/article/70f299ccb84846d5a2793a6bf3036c00
Autor:
Lavinia Rech, Peter P. Rainer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Inflammation plays a central role in cardiovascular diseases (CVD). One pathway under investigation is the innate immune DNA sensor cyclic GMP-AMP synthase (cGAS) and its downstream receptor stimulator of interferon genes (STING). cGAS-STING upregula
Externí odkaz:
https://doaj.org/article/cea2284bafe740d0ab2dcffd5036b35a