Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Peter Osei-Gyimah"'
Publikováno v:
Proceedings of the National Academy of Sciences. 78:636-639
The opiate receptor was purified from a Triton-solubilized preparation of rat neural membranes by the use of affinity chromatography. The affinity gel was prepared by coupling 14-beta-bromoacetamidomorphine, a newly synthesized ligand, to omega-amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a0ded4986b02a2e66be1a3c9c55205
https://doi.org/10.1073/pnas.78.1.636
https://doi.org/10.1073/pnas.78.1.636
Publikováno v:
Biochemical Pharmacology. 28:1807-1810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1cf2b1ca71403d58d55fafddb149a7
https://doi.org/10.1016/0006-2952(79)90546-x
https://doi.org/10.1016/0006-2952(79)90546-x
Publikováno v:
Journal of Medicinal Chemistry. 21:1173-1178
The synthesis and pharmacological activity of erythro and threo isomers of 1-(3',4',5'-trimethoxy-alpha-hydroxy-benzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, 2 and 3, are reported. The structural assignments of 2 and 3 are based upon NMR spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d75b85fcb89ac4e04df4c469637c8a
https://doi.org/10.1021/jm00209a019
https://doi.org/10.1021/jm00209a019
Autor:
Ahmad Seyed-Mozaffari, R. Suzanne Zukin, Sydney Archer, Peter Osei-Gyimah, Eric J. Simon, Rhoda Maneckjee, Theresa L. Gioannini, Josephine Michael
Publikováno v:
Journal of Medicinal Chemistry. 28:1950-1953
Condensation of the Grignard reagent derive from 2-[4-(allyloxy)phenyl]ethyl bromide (4b) with 7 alpha-acetyl-6,14-endo-ethenotetrahydrothebaine (5) furnished the (R) tertiary carbinol, 7, which upon methoxymercuration followed by treatment with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731f9f40f77c47b4433142e4ca48b545
https://doi.org/10.1021/jm00150a032
https://doi.org/10.1021/jm00150a032
Publikováno v:
Journal of Medicinal Chemistry. 24:212-214
A series of N-(cyclopropylmethyl)-14 beta-substituted-normorphine analogues was synthesized and tested for opioid agonist and antagonist activity in the guinea pig ileum and mouse vas deferens preparations. The 14 beta-bromo compound proved to be a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83deab9a61e805906855861e930c69bf
https://doi.org/10.1021/jm00134a018
https://doi.org/10.1021/jm00134a018
Publikováno v:
Journal of medicinal chemistry. 23(5)
A series of 4-[N-(aminoalkyl)amino]-1,2-dimethoxynaphthalenes was prepared and tested for radical curative activity in rhesus monkeys infected with P. cynomolgi. Some radical curative activity was observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83dc9a847f0528e3da0753852b7e9ca
https://pubmed.ncbi.nlm.nih.gov/6770088
https://pubmed.ncbi.nlm.nih.gov/6770088
Publikováno v:
Chemischer Informationsdienst. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4324233ebf3719d950154bd045916eb3
https://doi.org/10.1002/chin.198128355
https://doi.org/10.1002/chin.198128355
Publikováno v:
Chemischer Informationsdienst. 11
A series of 4-[N-(aminoalkyl)amino]-1,2-dimethoxynaphthalenes was prepared and tested for radical curative activity in rhesus monkeys infected with P. cynomolgi. Some radical curative activity was observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79a06db9371fe27c34b285aade28eb24
https://doi.org/10.1002/chin.198038190
https://doi.org/10.1002/chin.198038190
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7e1063b47e48bb33acf4b3ae0059b0
https://doi.org/10.1002/chin.197816225
https://doi.org/10.1002/chin.197816225