Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Peter Olausson"'
Publikováno v:
Pancasila: Jurnal Keindonesiaan. 2:163-178
The literature analyzing perspectives on Indonesia's golden years in the 2045 narrative is extensive and optimistic. But achieving 2045 is more challenging amid disruption conditions, especially after a multidimensional crisis because of COVID-19. Ci
Autor:
Paul J. Lombroso, Michael W. Salter, Peter Olausson, Timothy D. Moran, Deepa V. Venkitaramani, James Taylor
Publikováno v:
Neuroscience. 225:1-8
STriatal-Enriched protein tyrosine Phosphatase (STEP; PTPN5) is expressed in brain regions displaying adult neuroplasticity. STEP modulates neurotransmission by dephosphorylating regulatory tyrosine residues on its substrates. In this way, STEP inact
Publikováno v:
European Journal of Neuroscience. 35:300-308
Regulator of calmodulin (CaM) signaling (RCS), when phosphorylated by protein kinase A (PKA) on Ser55, binds to CaM and inhibits CaM-dependent signaling. RCS expression is high in the dorsal striatum, nucleus accumbens and amygdala, suggesting that t
Publikováno v:
Psychopharmacology. 212:321-328
We recently demonstrated that blocking specific nicotinic acetylcholine receptors (nAChRs) abolishes the conditioned reinforcing properties of ethanol-associated cues in rat, suggesting nAChRs as promising pharmacological targets for prevention of cu
Publikováno v:
Neuropsychopharmacology. 34:707-716
A history of exposure to stressors may be a predisposing factor for developing posttraumatic stress disorder (PTSD) after trauma. Extinction of conditioned fear appears to be impaired in PTSD, but the consequences of prior stress or excess glucocorti
Autor:
Peter Olausson, Jennifer J. Quinn, James A. Bibb, Jane R. Taylor, Ammar H. Hawasli, Zhen Yan, Janice W. Kansy, Ping Zhong, David R. Benavides, Ralph J. DiLeone
Publikováno v:
The Journal of Neuroscience. 27:12967-12976
Cyclin-dependent kinase 5 (Cdk5) regulates dopamine neurotransmission and has been suggested to serve as a homeostatic target of chronic psychostimulant exposure. To study the role of Cdk5 in the modulation of the cellular and behavioral effects of p
Autor:
Jane R. Taylor, Paul J. Lombroso, Evan Mills, Timothy D. Moran, Natalie C. Tronson, Surojit Paul, Deepa V. Venkitaramani, Michael W. Salter, Irina Ruchkina, Shawn Hakim, Peter Olausson
Publikováno v:
Biological Psychiatry. 61:1049-1061
Background Formation of long-term memories is critically dependent on extracellular-regulated kinase (ERK) signaling. Activation of the ERK pathway by the sequential recruitment of mitogen-activated protein kinases is well understood. In contrast, th
Autor:
Peter Olausson, Hayde Sanchez, Jane R. Taylor, James A. Bibb, Wendy J. Lynch, Eric J. Nestler
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4147-4152
Neuronal adaptations in striatal dopamine signaling have been implicated in enhanced responses to addictive drugs. Cyclin-dependent kinase 5 (Cdk5) regulates striatal dopamine signaling and is a downstream target gene of the transcription factor ΔFo
Autor:
Pouran Almstedt, Pär Sparén, Peter Olausson, Joakim Dillner, Björn Strander, K. Miriam Elfström
Publikováno v:
Journal of medical screening. 23(4)
Objectives Comprehensive nationwide monitoring and evaluation of screening through registry-based review of key indicators is necessary for programme optimization, especially as new tests and strategies are introduced. We aimed to investigate and rep
Autor:
Natalie C. Tronson, Peter Olausson, J. David Jentsch, Rachel L. Neve, Jane R. Taylor, Eric J. Nestler
Publikováno v:
The Journal of Neuroscience. 26:9196-9204
Alterations in motivation have been implicated in the pathophysiology of several psychiatric disorders, including substance abuse and depression. Repeated exposure to drugs of abuse or stress is known to persistently induce the transcription factor d