Výsledky vyhledávání - "Peter O. Wiebe"

Ptf1a Binds to and Activates Area III, a Highly Conserved Region of the Pdx1 Promoter That Mediates Early Pancreas-Wide Pdx1 Expression

Autor: Roland Stein, Christopher V.E. Wright, Peter O. Wiebe, Jay D. Kormish, Venus C. Roper, Kenneth S. Zaret, Yoshio Fujitani, Ninche I. Alston, Maureen Gannon

Publikováno v: Molecular and Cellular Biology. 27:4093-4104

The critical pancreatic transcription factor Pdx1 is expressed throughout the pancreas early but enriched in insulin-producing beta cells postnatally. Previous studies showed that the 5' conserved promoter regions areas I and II (Pdx1(PB)) direct end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e077e2c44df87d6d529fb79f12289c7
https://doi.org/10.1128/mcb.01978-06

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Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts11Edited by N.-H. Chua

Autor: Tanvi Panchal, Seung-Bum Lee, Henry Daniell, Peter O Wiebe

Publikováno v: Journal of Molecular Biology

The B subunits of enterotoxigenic Escherichia coli (LTB) and cholera toxin of Vibrio cholerae (CTB) are candidate vaccine antigens. Integration of an unmodified CTB-coding sequence into chloroplast genomes (up to 10,000 copies per cell), resulted in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f163d6d6fee916957c8947be79a7804

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Antibiotic-free chloroplast genetic engineering – an environmentally friendly approach

Autor: Alicia Fernandez-San Millan, Henry Daniell, Peter O Wiebe

Publikováno v: Trends in Plant Science. 6:237-239

Chloroplast genetic engineering offers several advantages over nuclear genetic engineering, including gene containment and hyperexpression. However, introducing thousands of copies of transgenes into the chloroplast genome amplifies the antibiotic re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::437f760caad2cf19c851223319f5c5d5
https://doi.org/10.1016/s1360-1385(01)01949-5

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Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function

Autor: W. Gray Jerome, Chad Carr, Greg Poffenberger, Alvin C. Powers, Jin Chen, Thomas L. Jetton, Zhongyi Chen, Alena Shostak, Wendell E. Nicholson, H. Scott Baldwin, Marcela Brissova, Jeannelle Kantz, Masakazu Shiota, Maureen Gannon, Peter O. Wiebe, David M. Bader

Publikováno v: Diabetes. 55(11)

To investigate molecular mechanisms controlling islet vascularization and revascularization after transplantation, we examined pancreatic expression of three families of angiogenic factors and their receptors in differentiating endocrine cells and ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439b092a3abc354988d782267267a449
https://pubmed.ncbi.nlm.nih.gov/17065333

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Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets

Autor: Michael J. Fowler, Peter O. Wiebe, Marcela Brissova, Alvin C. Powers, P. Charles Lin, Masakazu Shiota, Aramandla Radhika, Maureen Gannon, Alena Shostak

Publikováno v: Diabetes. 53(5)

Pancreatic islet transplantation is an emerging therapy for type 1 diabetes. To survive and function, transplanted islets must revascularize because islet isolation severs arterial and venous connections; the current paradigm is that islet revascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fa5d7dea82ad7e4f0137c8bfe84d74
https://pubmed.ncbi.nlm.nih.gov/15111502

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Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells

Autor: Christina A. Svitek, James K. Oeser, Richard M. O'Brien, Angela Eeds, Beth T. Stadelmaier, Peter O. Wiebe, Jared N. Boustead

It has recently been shown that adenoviral-mediated expression of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) in hepatocytes stimulates glucose-6-phosphatase catalytic subunit (G6Pase) gene expression. A combin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388ab0acd72755f0f05de30c3aa32342
https://europepmc.org/articles/PMC1223073/

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