Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Peter O Bauer"'
Autor:
Masahiro Kimura, Satoshi Wakita, Kotarou Ishikawa, Kazutaka Sekine, Satoshi Yoshikawa, Akira Sato, Kazuaki Okawa, Akinori Kashimura, Masayoshi Sakaguchi, Yasusato Sugahara, Daisuke Yamanaka, Naohito Ohno, Peter O Bauer, Fumitaka Oyama
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164367 (2016)
Chitotriosidase (Chit1) is an enzyme associated with various diseases, including Gaucher disease, chronic obstructive pulmonary disease, Alzheimer disease and cystic fibrosis. In this study, we first expressed mouse mature Chit1 fused with V5 and (Hi
Externí odkaz:
https://doaj.org/article/50a4482394a14c24bd9636a01d64d139
Autor:
Tomoyuki Yamanaka, Hon Kit Wong, Asako Tosaki, Peter O Bauer, Koji Wada, Masaru Kurosawa, Tomomi Shimogori, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93891 (2014)
In polyglutamine (polyQ) diseases including Huntington's disease (HD), mutant proteins containing expanded polyQ stretch form aggregates in neurons. Genetic or RNAi screenings in yeast, C. elegans or Drosophila have identified multiple genes modifyin
Externí odkaz:
https://doaj.org/article/208b97340db849a39bf28664846b4fb4
Autor:
José Miguel Laffita-Mesa, Jorge Michel Rodríguez Pupo, Raciel Moreno Sera, Yaimee Vázquez Mojena, Vivian Kourí, Leonides Laguna-Salvia, Michael Martínez-Godales, José A Valdevila Figueira, Peter O Bauer, Roberto Rodríguez-Labrada, Yanetza González Zaldívar, Martin Paucar, Per Svenningsson, Luís Velázquez Pérez
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70560 (2013)
Pathogenic CAG repeat expansion in the ataxin-2 gene (ATXN2) is the genetic cause of spinocerebellar ataxia type 2 (SCA2). Recently, it has been associated with Parkinsonism and increased genetic risk for amyotrophic lateral sclerosis (ALS). Here we
Externí odkaz:
https://doaj.org/article/550a10b8302d4eb4afec6a88a29d6819
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 1, p e1002883 (2013)
We computationally determined miRs that are significantly connected to molecular pathways by utilizing gene expression profiles in different cancer types such as glioblastomas, ovarian and breast cancers. Specifically, we assumed that the knowledge o
Externí odkaz:
https://doaj.org/article/e373c2a5bdc0404cbb00f48570bfb6bb
Autor:
Eri Tabata, Ikuto Kobayashi, Takuya Morikawa, Akinori Kashimura, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107254- (2023)
Summary: Placental mammals' ancestors were insectivores, suggesting that modern mammals may have inherited the ability to digest insects. Acidic chitinase (Chia) is a crucial enzyme hydrolyzing significant component of insects' exoskeleton in many sp
Externí odkaz:
https://doaj.org/article/9fb2dd4b297a47de897af4261532ec99
Autor:
Maiko Uehara, Eri Tabata, Mikoto Okuda, Yukari Maruyama, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Diet of the crab-eating monkey (Macaca fascicularis) consists of both plants and animals, including chitin-containing organisms such as crabs and insects. This omnivorous monkey has a high expression of acidic chitinase (CHIA) in the stomach
Externí odkaz:
https://doaj.org/article/f87e4f5baa2d4a98bf1fb882837ec934
Autor:
Masahiro Kimura, Takatoshi Umeyama, Satoshi Wakita, Kazuaki Okawa, Masayoshi Sakaguchi, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
MethodsX, Vol 7, Iss , Pp 100881- (2020)
Fluorophore-assisted carbohydrate electrophoresis (FACE) enables detection and quantification of degradation products from artificial and natural chitin substrates such as 4-NP-(GlcNAc)2, (GlcNAc)4 and colloidal chitin. The FACE method has been impro
Externí odkaz:
https://doaj.org/article/b87959e273754f49b78e62d76986b03b
Autor:
Maiko Uehara, Chinatsu Takasaki, Satoshi Wakita, Yasusato Sugahara, Eri Tabata, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
Molecules, Vol 27, Iss 2, p 409 (2022)
Chitooligosaccharides, the degradation products of chitin and chitosan, possess anti-bacterial, anti-tumor, and anti-inflammatory activities. The enzymatic production of chitooligosaccharides may increase the interest in their potential biomedical or
Externí odkaz:
https://doaj.org/article/87e3aba29d10483faf2a28c00f03bb94
Autor:
Satoshi Wakita, Yasusato Sugahara, Masayuki Nakamura, Syunsuke Kobayashi, Kazuhisa Matsuda, Chinatsu Takasaki, Masahiro Kimura, Yuta Kida, Maiko Uehara, Eri Tabata, Koji Hiraoka, Shiro Seki, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
Molecules, Vol 26, Iss 21, p 6706 (2021)
Chitooligosaccharides exhibit several biomedical activities, such as inflammation and tumorigenesis reduction in mammals. The mechanism of the chitooligosaccharides’ formation in vivo has been, however, poorly understood. Here we report that mouse
Externí odkaz:
https://doaj.org/article/c7e3c168daf14ca5936ba77f5e7f2ff1
Autor:
Eri Tabata, Akinori Kashimura, Satoshi Wakita, Misa Ohno, Masayoshi Sakaguchi, Yasusato Sugahara, Yoshihiro Kino, Vaclav Matoska, Peter O. Bauer, Fumitaka Oyama
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Chitin, a polymer of N-acetyl-D-glucosamine (GlcNAc), functions as a major structural component in crustaceans, insects and fungi and is the second most abundant polysaccharide in the nature. Although these chitin-containing organisms have b
Externí odkaz:
https://doaj.org/article/9c19af425e384cc88b5506bca30a9310