Likelihood of mechanistic roles for dopaminergic, serotonergic and glutamatergic receptors in tardive dyskinesia: A comparison of genetic variants in two independent patient populations

Autor: Svetlana A Ivanova, Anton JM Loonen, P Roberto Bakker, Maxim B Freidin, Nienke J ter Woerds, Asmar FY Al Hadithy, Arkadiy V Semke, Olga Yu Fedorenko, Jacobus RBJ Brouwers, Nikolay A Bokhan, Jim van Os, Peter N van Harten, Bob Wilffert

Publikováno v: SAGE Open Medicine, Vol 4 (2016)

Objectives: An established theory for the pathogenesis of tardive dyskinesia is disturbed dopaminergic receptor sensitivity and/or dopaminergic intracellular signaling. We examined associations between genetic variants of neurotransmitter receptors a

Externí odkaz: https://doaj.org/article/167fc5058fec4776ad26b3a0956f3e6b

Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study.

Autor: P Roberto Bakker, Egbert Bakker, Najaf Amin, Cornelia M van Duijn, Jim van Os, Peter N van Harten

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36561 (2012)

ObjectiveFour types of antipsychotic-induced movement disorders: tardive dyskinesia (TD), parkinsonism, akathisia and tardive dystonia, subtypes of TD (orofacial and limb truncal dyskinesia), subtypes of parkinsonism (rest tremor, rigidity, and brady

Externí odkaz: https://doaj.org/article/e499a3d369454b9cb1adbf041a9236ad

Long-stay psychiatric patients: a prospective study revealing persistent antipsychotic-induced movement disorder.

Autor: P Roberto Bakker, Izaäk W de Groot, Jim van Os, Peter N van Harten

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e25588 (2011)

OBJECTIVE: The purpose of this study was to assess the frequency of persistent drug-induced movement disorders namely, tardive dyskinesia (TD), parkinsonism, akathisia and tardive dystonia in a representative sample of long-stay patients with chronic

Externí odkaz: https://doaj.org/article/13a36ca1724d4fb1b93597a5617bed79

Movement Disorders and Mortality in Severely Mentally Ill Patients

Autor: Anne E Willems, Charlotte L Mentzel, Pieter Roberto Bakker, Jim Van Os, Diederik E Tenback, Petra Gelan, Erna Daantjes, Glenn E Matroos, Hans W Hoek, Peter N Van Harten

Publikováno v: Schizophr Bull
Schizophrenia Bulletin, 48(4), 766-773. Oxford University Press
Schizophrenia Bulletin, 48(4):sbac037, 766-773. Oxford University Press

Background and Hypothesis There is a substantial gap in life expectancy between patients with severe mental illness (SMI) and the general population and it is important to understand which factors contribute to this difference. Research suggests an a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5f18d9e75d1438f833d51f73bed924
https://doi.org/10.1093/schbul/sbac037

The effect on relapse rate and psychiatric symptomatology

Autor: Mushde Shakir, Anne E. Willems, Peter N. van Harten, Remko van Lutterveld, Diederik E. Tenback

Publikováno v: Schizophrenia Research, 243, 187-194. Elsevier Science

BACKGROUND: There is little evidence to support the use of antipsychotic polypharmacy, and there are concerns about safety and side effects. Nonetheless, it is commonly used in the treatment of long-term inpatients with schizophrenia. This study inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a34341f7a677b1fc6d9ab7ecf81ea0e
https://doi.org/10.1016/j.schres.2022.03.008