Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Peter N Devreotes"'
Autor:
Qixin Yang, Yuchuan Miao, Leonard J Campanello, Matt J Hourwitz, Bedri Abubaker-Sharif, Abby L Bull, Peter N Devreotes, John T Fourkas, Wolfgang Losert
Publikováno v:
eLife, Vol 11 (2022)
Electrotaxis, the directional migration of cells in a constant electric field, is important in regeneration, development, and wound healing. Electrotaxis has a slower response and a smaller dynamic range than guidance by other cues, suggesting that t
Externí odkaz:
https://doaj.org/article/298f898d85b840ee900b7b1f09036bc2
Autor:
Elisabeth Ghabache, Yuansheng Cao, Yuchuan Miao, Alex Groisman, Peter N Devreotes, Wouter‐Jan Rappel
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 12, Pp n/a-n/a (2021)
Abstract Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force patterns and cytoskeletal distributions in Dic
Externí odkaz:
https://doaj.org/article/4e3e8f1a87ba4047a333ba182bf5d986
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1008803 (2021)
During the last decade, a consensus has emerged that the stochastic triggering of an excitable system drives pseudopod formation and subsequent migration of amoeboid cells. The presence of chemoattractant stimuli alters the threshold for triggering t
Externí odkaz:
https://doaj.org/article/b0514cdcea0a4b858d11cf6895b42937
Autor:
Oliver Hoeller, Jared E Toettcher, Huaqing Cai, Yaohui Sun, Chuan-Hsiang Huang, Mariel Freyre, Min Zhao, Peter N Devreotes, Orion D Weiner
Publikováno v:
PLoS Biology, Vol 14, Iss 2, p e1002381 (2016)
For directional movement, eukaryotic cells depend on the proper organization of their actin cytoskeleton. This engine of motility is made up of highly dynamic nonequilibrium actin structures such as flashes, oscillations, and traveling waves. In Dict
Externí odkaz:
https://doaj.org/article/734dfa607efc4143957f29db080a679a
Autor:
Minxi Hu, Houpu Li, Kan Zhu, Liang Guo, Min Zhao, Huiwang Zhan, Peter N. Devreotes, Quan Qing
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Different exogenous electric fields (EF) can guide cell migration, disrupt proliferation, and program cell development. Studies have shown that many of these processes were initiated at the cell membrane, but the mechanism has been unclear,
Externí odkaz:
https://doaj.org/article/608fc7fe260049c38aadba1579625347
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/49e0139ab3824c299e6324c2b200cc5a
Autor:
Bernhard Roppenser, Hyunwoo Kwon, Veronica Canadien, Risheng Xu, Peter N Devreotes, Sergio Grinstein, John H Brumell
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71015 (2013)
SopB is a type 3 secreted effector with phosphatase activity that Salmonella employs to manipulate host cellular processes, allowing the bacteria to establish their intracellular niche. One important function of SopB is activation of the pro-survival
Externí odkaz:
https://doaj.org/article/5ad027cc9e2949bd9e0c705f1e514df3
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003122 (2013)
Chemotaxis involves the coordinated action of separable but interrelated processes: motility, gradient sensing, and polarization. We have hypothesized that these are mediated by separate modules that account for these processes individually and that,
Externí odkaz:
https://doaj.org/article/9e877a84131a43c8a9f83b8b84e322b4
Autor:
Tatsat Banerjee, Satomi Matsuoka, Debojyoti Biswas, Yuchuan Miao, Dhiman Sankar Pal, Yoichiro Kamimura, Masahiro Ueda, Peter N. Devreotes, Pablo A. Iglesias
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract The plasma membrane is widely regarded as the hub of the numerous signal transduction activities. Yet, the fundamental biophysical mechanisms that spatiotemporally compartmentalize different classes of membrane proteins remain unclear. Using
Externí odkaz:
https://doaj.org/article/fc58346f19f04ff1a949c99660d2891f
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundStatin therapy has been shown to reduce mortality in a wide range of cancer types and overall stages. Still, there is uncertainty about its efficacy in increasing survival among advanced cancer patients.MethodsWe conducted a meta-analysis w
Externí odkaz:
https://doaj.org/article/fb61911cc21040b6928d645e249992e7