Two new types of assays to determine protein concentrations in biological fluids using mass spectrometry of intact proteins with cystatin C in spinal fluid as an example

Autor: Peter Michelsen, Anders Grubb, Niklas Tyrefors

Publikováno v: Scandinavian Journal of Clinical & Laboratory Investigation; 74(6), pp 546-554 (2014)
Scandinavian Journal of Clinical and Laboratory Investigation

There is no reference method that is generally acknowledged to be unbiased for the determination of the concentration of any protein in biological fluids. This is probably because mass spectrometry (MS) methods acknowledged as reference methods for d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54d87ad7501eb8fab4c7c24eebdb1c2
https://doi.org/10.3109/00365513.2014.917697

The potential of inductively coupled plasma mass spectrometry detection for high-performance liquid chromatography combined with accurate mass measurement of organic pharmaceutical compounds

Autor: Peter Michelsen, Abou-Shakra F, Bengt-Olof Axelsson, Magnus Jörntén-Karlsson

Publikováno v: Rapid Communications in Mass Spectrometry. 15:375-385

Quantification of unknown components in pharmaceutical, metabolic and environmental samples is an important but difficult task. Most commonly used detectors (like UV, RI or MS) require standards of each analyte for accurate quantification. Even if th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8351507d89efbc294d80aa8e2079fc04
https://doi.org/10.1002/rcm.238

Molecular species of sphingomyelin: determination by high-performance liquid chromatography/mass spectrometry with electrospray and high-performance liquid chromatography/tandem mass spectrometry with atmospheric pressure chemical ionization

Autor: Peter Michelsen, Anders Å. Karlsson, Göran Odham

Publikováno v: Journal of Mass Spectrometry. 33:1192-1198

In a sphingomyelin-enriched sample of polar lipids from bovine milk, molecular species of intact sphingomyelin were separated by normal-phase high-performance liquid chromatography and detected by mass spectrometry (MS) for structural information. Fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5faed66a425e304eeea9cd06fd49ceee
https://doi.org/10.1002/(sici)1096-9888(199812)33:12<1192::aid-jms735>3.0.co

Separation of Polyphosphoinositides Using Normal-Phase High-Performance Liquid Chromatography and Evaporative Light Scattering Detection or Electrospray Mass Spectrometry

Autor: Göran Odham, Torsten Gunnarsson, Peter Michelsen, Bengt Jergil, Anders Karlsson, Lars Ekblad

Publikováno v: Analytical Biochemistry. 254:293-296

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a0e12bccaa3d45f1648717a1fe2c59
https://doi.org/10.1006/abio.1997.2430

Normal-phase Liquid Chromatography Class Separation and Species Determination of Phospholipids Utilizing Electrospray Mass Spectrometry/Tandem Mass Spectrometry

Autor: Peter Michelsen, Göran Odham, Anders Å Karlsson, Åsmund Larsen

Publikováno v: Rapid Communications in Mass Spectrometry. 10:775-780

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9541e818bd5871b72e94c5de6f907758
https://doi.org/10.1002/(sici)1097-0231(199605)10:7<775::aid-rcm570>3.0.co