Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Peter Mattjus"'
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interes
Externí odkaz:
https://doaj.org/article/cab525f2ef26429a89e864bfa5c29296
Autor:
Anders P E Backman, Josefin Halin, Henrik Nurmi, Anna Möuts, Matti A Kjellberg, Peter Mattjus
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209230 (2018)
The glycolipid transfer protein, GLTP, can be found in the cytoplasm, and it has a FFAT-like motif (two phenylalanines in an acidic tract) that targets it to the endoplasmic reticulum (ER). We have previously shown that GLTP can bind to a transmembra
Externí odkaz:
https://doaj.org/article/ac638bdf7ab34312bc98e00be044ecdd
Autor:
Yu-Ping Zhu, Meng Wang, Yuancai Xiang, Lu Qiu, Shaofan Hu, Zhengwen Zhang, Peter Mattjus, Xiaomei Zhu, Yiguo Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2927 (2018)
Normal growth and development, as well as adaptive responses to various intracellular and environmental stresses, are tightly controlled by transcriptional networks. The evolutionarily conserved genomic sequences across species highlights the archite
Externí odkaz:
https://doaj.org/article/48553871e81e4d7bb672ce3749196ced
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143385 (2015)
Ceramides can be delivered to cultured cells without solvents in the form of complexes with cholesteryl phosphocholine. We have analysed the delivery of three different radiolabeled D-erythro-ceramides (C6-Cer, C10-Cer and C16-Cer) to HeLa cells, and
Externí odkaz:
https://doaj.org/article/50ccbc9b6d514c9580d1bfc41bde4d03
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97263 (2014)
The glycolipid transfer protein (GLTP) catalyzes the binding and transport of glycolipids, but not phospholipids or neutral lipids. With its all-alpha helical fold, it is the founding member for a new superfamily, however its biological role still re
Externí odkaz:
https://doaj.org/article/f0f473adf22944d68491b5a42c72299f
Autor:
Matti A Kjellberg, Peter Mattjus
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0070283.].
Externí odkaz:
https://doaj.org/article/a22dbb4eb10e49b8877aa2ec064e1b01
Autor:
Matti A Kjellberg, Peter Mattjus
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70283 (2013)
Members of the glycolipid transfer protein superfamily (GLTP) are found from animals and fungi to plants and red micro-alga. Eukaryotes that encode the glucosylceramide synthase responsible for the synthesis of glucosylceramide, the precursor for mos
Externí odkaz:
https://doaj.org/article/65dd4b77bc714b039b05e3050f73bde5
Autor:
Henrik Nurmi, Anders P.E. Backman, Josefin Halin, Max Lönnfors, Tomas Blom, Pia Roos-Mattjus, Peter Mattjus
Publikováno v:
Journal of Biological Chemistry. 299:104607
Autor:
Rongzhen Deng, Ze Zheng, Shaofan Hu, Meng Wang, Jing Feng, Peter Mattjus, Zhengwen Zhang, Yiguo Zhang
Since Nrf1 and Nrf2 are essential for regulating the lipid metabolism pathways, their dysregulation has thus been shown to be critically involved in the non-controllable inflammatory transformation into cancer. Herein, we have explored the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6f169aab2b1bb8300413d842b70df4f
https://doi.org/10.1101/2021.09.29.462358
https://doi.org/10.1101/2021.09.29.462358
Autor:
Anders P. E. Backman, Peter Mattjus
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(11)
Lipid bilayers function as boundaries that enclose their content from the surrounding media, and the composition of different membrane types is accurately and dynamically tailored so that they can perform their function. To achieve this balance, lipi