Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Peter Marynen"'
Autor:
Joke Vandewalle, Marion Langen, Marlen Zschaetzsch, Bonnie Nijhof, Jamie M. Kramer, Hilde Brems, Marijke Bauters, Elsa Lauwers, Mohammed Srahna, Peter Marynen, Patrik Verstreken, Annette Schenck, Bassem A. Hassan, Guy Froyen
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/779bbb56762945a9ac29530eafa5a67c
MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.
Autor:
Mathijs Baens, Luca Bonsignore, Riet Somers, Charlotte Vanderheydt, Stephen D Weeks, Jenny Gunnarsson, Ewa Nilsson, Robert G Roth, Margot Thome, Peter Marynen
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103774 (2014)
Mucosa-associated lymphoid tissue 1 (MALT1) controls antigen receptor-mediated signalling to nuclear factor κB (NF-κB) through both its adaptor and protease function. Upon antigen stimulation, MALT1 forms a complex with BCL10 and CARMA1, which is e
Externí odkaz:
https://doaj.org/article/d497c7b166e14fea9cbd657798562bcf
Autor:
Lieselot Vanmarsenille, Jelle Verbeeck, Stefanie Belet, Anton J Roebroek, Tom Van de Putte, Joke Nevelsteen, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Peter Marynen, Guy Froyen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64144 (2013)
Members of the Nuclear eXport Factor (NXF) family are involved in the export of mRNA from the nucleus to the cytoplasm, or hypothesized to play a role in transport of cytoplasmic mRNA. We previously reported on the loss of NXF5 in a male patient with
Externí odkaz:
https://doaj.org/article/de03510294ce45598248e9eef196dd74
Autor:
Joke Vandewalle, Marion Langen, Marlen Zschätzsch, Bonnie Nijhof, Jamie M Kramer, Hilde Brems, Marijke Bauters, Elsa Lauwers, Mohammed Srahna, Peter Marynen, Patrik Verstreken, Annette Schenck, Bassem A Hassan, Guy Froyen
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81791 (2013)
We recently reported that duplication of the E3 ubiquitin ligase HUWE1 results in intellectual disability (ID) in male patients. However, the underlying molecular mechanism remains unknown. We used Drosophila melanogaster as a model to investigate th
Externí odkaz:
https://doaj.org/article/5ed43426dfef4d72af665090c208249c
Autor:
Katrien Van Roosbroeck, Jan Cools, Daan Dierickx, José Thomas, Peter Vandenberghe, Michel Stul, Jan Delabie, Chris De Wolf-Peeters, Peter Marynen, Iwona Wlodarska
Publikováno v:
Haematologica, Vol 95, Iss 3 (2010)
We report 2 ALK-positive large B-cell lymphoma cases showing granular cytoplasmic and cytoplasmic/nuclear ALK immunostaining in which cryptic ALK rearrangements were identified by fluorescent in situ hybridization and molecular analysis. In the first
Externí odkaz:
https://doaj.org/article/ed9e686eae7840cf8c78574f87175a28
Autor:
Peter Van Loo, Thomas Tousseyn, Vera Vanhentenrijk, Daan Dierickx, Agnieszka Malecka, Isabelle Vanden Bempt, Gregor Verhoef, Jan Delabie, Peter Marynen, Patrick Matthys, Chris De Wolf-Peeters
Publikováno v:
Haematologica, Vol 95, Iss 3 (2010)
Background Gene expression profiling has successfully identified the prognostic significance of the host response in lymphomas. The aggressive T-cell/histiocyte-rich large B-cell lymphoma and the indolent nodular lymphocyte-predominant Hodgkin’s ly
Externí odkaz:
https://doaj.org/article/77b7e51dafda45e2b296df1197fd2314
Autor:
Wouter Bossuyt, Natalie De Geest, Stein Aerts, Iris Leenaerts, Peter Marynen, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 7, Iss 2, p e40 (2009)
The acquisition of terminal cell fate and onset of differentiation are instructed by cell type-specific master control genes. Loss of differentiation is frequently observed during cancer progression, but the underlying causes and mechanisms remain po
Externí odkaz:
https://doaj.org/article/d936a21983004c358a11167c18610198
Autor:
Wouter Bossuyt, Avedis Kazanjian, Natalie De Geest, Sofie Van Kelst, Gert De Hertogh, Karel Geboes, Greg P Boivin, Judith Luciani, Francois Fuks, Marinee Chuah, Thierry VandenDriessche, Peter Marynen, Jan Cools, Noah F Shroyer, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 7, Iss 2, p e39 (2009)
Colon cancer accounts for more than 10% of all cancer deaths annually. Our genetic evidence from Drosophila and previous in vitro studies of mammalian Atonal homolog 1 (Atoh1, also called Math1 or Hath1) suggest an anti-oncogenic function for the Ato
Externí odkaz:
https://doaj.org/article/fb9b56ff2e344a0b8af06bba6b4c590a
Autor:
Stefan Lehnert, Peter Van Loo, Pushpike J Thilakarathne, Peter Marynen, Geert Verbeke, Frans C Schuit
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4456 (2009)
This paper connects Alu repeats, the most abundant repetitive elements in the human genome and microRNAs, small RNAs that alter gene expression at the post-transcriptional level. Base-pair complementarity could be demonstrated between the seed sequen
Externí odkaz:
https://doaj.org/article/a33286440be04c1e99d4f0f7acf572cc
Autor:
Heidi Noels, Riet Somers, Hongxiang Liu, Hongtao Ye, Ming-Qing Du, Christiane De Wolf-Peeters, Peter Marynen, Mathijs Baens
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4822 (2009)
BACKGROUND: The translocation t(11;18)(q21;q21) is the most frequent chromosomal aberration associated with MALT lymphoma and results in constitutive NF-kappaB activity via the expression of an API2-MALT1 fusion protein. The properties of the recipro
Externí odkaz:
https://doaj.org/article/802c0e5b37954c42b9f291eadd379e30