Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peter Marschall"'
Publikováno v:
Nucleic Acids Research. 27:3159-3167
Two synthetic hammerhead ribozymes, one unmodified and the other with 2"-modifications and four phosphorothioate groups, targeting a single GUA site in the luciferase mRNA, were compared for their inhibition of gene expression in cell cultureand thei
Autor:
Georg Sczakiel, Fritz Eckstein, Ingo Oelze, Matthias Homann, Peter Marschall, Martin Tabler, Robert Hormes
Publikováno v:
Nucleic Acids Research. 25:769-775
The length requirements of the antisense portion of hammerhead ribozymes for efficacy in living cells was investigated. The HIV-1tat-directed asymmetric hammerhead ribozyme alphaYRz195 was used with a 195 nt 3'-antisense arm and a 3 nt 5'-antisense p
Autor:
Hans-Peter Marschall, Mahir Tokić, Alexander Chuchalin, Dejan Dokic, Thomas Petri, Maryna Zakharova
Publikováno v:
BMC Pulmonary Medicine, Vol 13, Iss 1, p 5 (2013)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Acute exacerbations of chronic bronchitis (AECB), including chronic obstructive pulmonary disease (AECOPD), represent a substantial patient burden. Few data exist on outpatient antibiotic management for AECB/AECOPD in Eastern/South Eastern
Autor:
Ulrich Kintscher, Rebecca Hugel, Jana Reinemund, Peter Walden, Ulrike Grittner, Rudolf Volkmer, Frank S. Zollmann, Jan H. Schefe, Antonia Hope, Yaosi Li, Sebastian Kirsch, Wolfgang Maier, Thomas Unger, Andreas Schlosser, Johannes Kornhuber, Heiko Funke-Kaiser, Kristin Schmerbach, Sylvia Scheele, Jennifer Schmitz, Heike Kölsch, Lutz Frölich, Peter Marschall, Sabrina Klare, Jens Schacherl, Petra Goldin-Lang, Kerstin Seidel, Julia Schimkus, Michael G. Klein, Oliver Peters, Mario Menk
Publikováno v:
Journal of Neuroscience, 32(47), 16807-16820. Society for Neuroscience
Genetic factors strongly contribute to the pathogenesis of sporadic Alzheimer's disease (AD). Nevertheless, genome-wide association studies only yielded single nucleotide polymorphism loci of moderate importance. In contrast, microsatellite repeats a
Publikováno v:
Cellular and Molecular Neurobiology. 14:523-538
1. Ribozymes can be designed to cleave in trans, i.e. several substrate molecules can be turned over by one molecule of the catalytic RNA. Only small molecular weight ribozymes, or small ribozymes, are discussed in this review with particular emphasi
Autor:
Mauro Campos Trindade, Cláudia Carvalhinho Windmöller, Helena Eugênia Leonhardt Palmieri, Otávio Eurico de Aquino Branco, Peter Marschall Fleming, Carlos Alberto de Carvalho Filho, Walter Alves Durão Júnior, José Bento Borba da Silva
Publikováno v:
Journal of environmental monitoring : JEM. 11(5)
This work describes an investigation of mercury contamination in an abandoned gold mining site in the rural area of Descoberto, Minas Gerais, Brazil, whose inhabitants have reported "silver balls" present in the soil. Different granulometric fraction
Autor:
William C. Earnshaw, Zoia Larin, Adrian Willmott, Peter Marschall, Elaine R. Levy, Anas M Alazami, José E. Mejía
Publikováno v:
Genomics. 79(3)
In a comparative study, we show that human artificial chromosome (HAC) vectors based on alpha-satellite (alphoid) DNA from chromosome 17 but not the Y chromosome regularly form HACs in HT1080 human cells. We constructed four structurally similar HAC
Publikováno v:
Polar Biology. 11
Microscopic anatomy, functional morphology, and ultrastructure of the stomach of the antarctic krill Euphausia superba Dana were investigated by means of serial sections, scanning and transmission electron microscopy, and video technique. A separatio
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Autor:
Walter Alves Durão Júnior1, Helena Eugênia Leonhardt Palmieri2, Mauro Campos Trindade3, Otávio Eurico de Aquino Branco2, Carlos Alberto Carvalho Filho2, Peter Marschall Fleming2, José Bento Borba da Silva1, Cláudia Carvalhinho Windmöller1
Publikováno v:
Journal of Environmental Monitoring. May2009, Vol. 11 Issue 5, p1056-1063. 8p.