Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Peter Maček"'
Autor:
Eva Kočar, Tea Lenarčič, Vesna Hodnik, Anastasija Panevska, Yunjie Huang, Gregor Bajc, Rok Kostanjšek, Anjaparavanda P. Naren, Peter Maček, Gregor Anderluh, Kristina Sepčić, Marjetka Podobnik, Matej Butala
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Aegerolysins are proteins produced by bacteria, fungi, plants and protozoa. The most studied fungal aegerolysins share a common property of interacting with membranes enriched with cholesterol in combination with either sphingomyelin or cera
Externí odkaz:
https://doaj.org/article/bf82f07acaef4c448d00464a1303d152
Autor:
Maruša Novak, Kristina Sepčić, Nada Kraševec, Igor Križaj, Peter Maček, Gregor Anderluh, Graziano Guella, Ines Mancini
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 9051-9069 (2014)
Ethanolic extracts of mycelia from Aspergillus niger (strain N402) grown in liquid media were observed to have haemolytic activity on bovine erythrocytes. This haemolytic activity decreased significantly during the time of growth (1–3 days). Moreov
Externí odkaz:
https://doaj.org/article/ee8350ce38224260b3631bf8c93601d1
Autor:
Davor Obradović, Rok Gašperšič, Simon Caserman, Adrijana Leonardi, Maja Jamnik, Zdravko Podlesek, Katja Seme, Gregor Anderluh, Igor Križaj, Peter Maček, Matej Butala
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159231 (2016)
The periodontopathogen Aggregatibacter actinomycetemcomitans synthesizes several virulence factors, including cytolethal distending toxin (CDT). The active CDT holoenzyme is an AB-type tripartite genotoxin that affects eukaryotic cells. Subunits CdtA
Externí odkaz:
https://doaj.org/article/aa529f56ce9f47289a0712dfa8cc6d2e
Autor:
Nataša Resnik, Urška Repnik, Mateja Erdani Kreft, Kristina Sepčić, Peter Maček, Boris Turk, Peter Veranič
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137878 (2015)
Cholesterol content can vary distinctly between normal and cancer cells, with elevated levels in cancer cells. Here, we investigated cholesterol sequestration with methyl-β-cyclodextrin (MCD), and pore-formation with the ostreolysin A/pleurotolysin
Externí odkaz:
https://doaj.org/article/3dd2f65687474744bf70f6324e0d1e5e
Autor:
Matej Skočaj, Nataša Resnik, Maja Grundner, Katja Ota, Nejc Rojko, Vesna Hodnik, Gregor Anderluh, Andrzej Sobota, Peter Maček, Peter Veranič, Kristina Sepčić
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92783 (2014)
Ostreolysin A (OlyA) is an ∼15-kDa protein that has been shown to bind selectively to membranes rich in cholesterol and sphingomyelin. In this study, we investigated whether OlyA fluorescently tagged at the C-terminal with mCherry (OlyA-mCherry) la
Externí odkaz:
https://doaj.org/article/ba3cbb4164a54b8a9f0081467e9860a3
Autor:
Yunjie Huang, Vesna Hodnik, Kristina Sepčić, Rok Kostanjšek, Peter Maček, Marjetka Podobnik, Gregor Anderluh, Anjaparavanda P. Naren, Matej Butala, Tea Lenarčič, Eva Kočar, Gregor Bajc, Anastasija Panevska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific reports, vol. 11, no. 6572, 2021.
Scientific Reports
Scientific reports, vol. 11, no. 6572, 2021.
Aegerolysins are proteins produced by bacteria, fungi, plants and protozoa. The most studied fungal aegerolysins share a common property of interacting with membranes enriched with cholesterol in combination with either sphingomyelin or ceramide phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a497045b7e7504758325df9cc10221
https://doi.org/10.1038/s41598-021-85956-2
https://doi.org/10.1038/s41598-021-85956-2
Autor:
Nataša Resnik, Jaka Razinger, Matej Skočaj, Anastasija Panevska, Vesna Hodnik, Špela Modic, Peter Veranič, Kristina Sepčić, Miki Zarić, Maruša Novak, Peter Maček, Sara Podržaj, Ivana Pavlic
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Aegerolysins ostreolysin A (OlyA) and pleurotolysin A (PlyA), and pleurotolysin B (PlyB) with the membrane-attack-complex/perforin domain are proteins from the mushroom genus Pleurotus. Upon binding to sphingomyelin/cholesterol-enriched membranes, Ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a353fddd482e9322d6ef295ed06b32
https://doi.org/10.1038/s41598-019-41450-4
https://doi.org/10.1038/s41598-019-41450-4
Autor:
Mateja Erdani Kreft, Apolonija Bedina Zavec, Matej Skočaj, Maja Grundner, Kristina Sepčić, Graziano Guella, Igor Križaj, Peter Maček, Nataša Resnik, Yang Yu, Adrijana Leonardi, Peter Veranič, Robert Frangež
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1858:2882-2893
Ostreolysin A (OlyA) is a 15-kDa protein that binds selectively to cholesterol/sphingomyelin membrane nanodomains. This binding induces the production of extracellular vesicles (EVs) that comprise both microvesicles with diameters between 100nm and 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c6ad8fdb1466bc91c1f2637e0daa37
https://doi.org/10.1016/j.bbamem.2016.08.015
https://doi.org/10.1016/j.bbamem.2016.08.015
Autor:
Monika C. Žužek, Kristina Sepčić, Milka Vrecl, Uroš Diacci, Peter Maček, Monika Babnik, Robert Frangež
Publikováno v:
Toxicology in Vitro. 29:2015-2021
Ostreolysin A/pleurotolysin B (OlyA/PlyB) is a binary pore-forming protein complex that produces a rapid cardiorespiratory arrest. Increased tonus of the coronary vascular wall produced by OlyA/PlyB may lead to ischemia, arrhythmias, the hypoxic inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2442434fa812c495c9171872657fcfb2
https://doi.org/10.1016/j.tiv.2015.08.014
https://doi.org/10.1016/j.tiv.2015.08.014
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1861(7)
Ceramide phosphoethanolamine (CPE) is the major sphingolipid in invertebrates and in some bacterial species. It has been also detected in mammalian cells, although only in trace amounts. Complete understanding of the biophysical and physiological rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430556125ae3be3e330ff61dc3498402
https://pubmed.ncbi.nlm.nih.gov/31067435
https://pubmed.ncbi.nlm.nih.gov/31067435