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Barriers to the ready adoption of biocatalysis into asymmetric synthesis for early stage medicinal chemistry are addressed, using ketone reduction by alcohol dehydrogenase as a model reaction. An efficient substrate screening approach is used to show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349b11e03ef5bcc2d7b7a41664756318
https://doi.org/10.26434/chemrxiv.13134767
https://doi.org/10.26434/chemrxiv.13134767
Autor:
Holly A. Reeve, Kylie A. Vincent, Katrina S. Madden, Peter M.T. Todd, Kouji Urata, Angela J. Russell
Barriers to the ready adoption of biocatalysis into asymmetric synthesis for early stage medicinal chemistry are addressed, using ketone reduction by alcohol dehydrogenase as a model reaction. An efficient substrate screening approach is used to show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae6d9df81387a16c095aacf8d5e9b49
https://doi.org/10.26434/chemrxiv.13134767.v1
https://doi.org/10.26434/chemrxiv.13134767.v1