Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Peter M. Spooner"'
Autor:
Dan E Arking, M Juhani Junttila, Philippe Goyette, Adriana Huertas-Vazquez, Mark Eijgelsheim, Marieke T Blom, Christopher Newton-Cheh, Kyndaron Reinier, Carmen Teodorescu, Audrey Uy-Evanado, Naima Carter-Monroe, Kari S Kaikkonen, Marja-Leena Kortelainen, Gabrielle Boucher, Caroline Lagacé, Anna Moes, XiaoQing Zhao, Frank Kolodgie, Fernando Rivadeneira, Albert Hofman, Jacqueline C M Witteman, André G Uitterlinden, Roos F Marsman, Raha Pazoki, Abdennasser Bardai, Rudolph W Koster, Abbas Dehghan, Shih-Jen Hwang, Pallav Bhatnagar, Wendy Post, Gina Hilton, Ronald J Prineas, Man Li, Anna Köttgen, Georg Ehret, Eric Boerwinkle, Josef Coresh, W H Linda Kao, Bruce M Psaty, Gordon F Tomaselli, Nona Sotoodehnia, David S Siscovick, Greg L Burke, Eduardo Marbán, Peter M Spooner, L Adrienne Cupples, Jonathan Jui, Karen Gunson, Y Antero Kesäniemi, Arthur A M Wilde, Jean-Claude Tardif, Christopher J O'Donnell, Connie R Bezzina, Renu Virmani, Bruno H C H Stricker, Hanno L Tan, Christine M Albert, Aravinda Chakravarti, John D Rioux, Heikki V Huikuri, Sumeet S Chugh
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002158 (2011)
Sudden cardiac death (SCD) continues to be one of the leading causes of mortality worldwide, with an annual incidence estimated at 250,000-300,000 in the United States and with the vast majority occurring in the setting of coronary disease. We perfor
Externí odkaz:
https://doaj.org/article/66b3fe689b1d46a3b42f17472cd2611c
Autor:
Dan E Arking, Kyndaron Reinier, Wendy Post, Jonathan Jui, Gina Hilton, Ashley O'Connor, Ronald J Prineas, Eric Boerwinkle, Bruce M Psaty, Gordon F Tomaselli, Thomas Rea, Nona Sotoodehnia, David S Siscovick, Gregory L Burke, Eduardo Marban, Peter M Spooner, Aravinda Chakravarti, Sumeet S Chugh
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9879 (2010)
BackgroundExisting studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic det
Externí odkaz:
https://doaj.org/article/51ac1a05490642358c7c387f28fe040d
Autor:
Gustavo J. Volpe, John Moxley, Joao A.C. Lima, Tony Killian, Peter M. Spooner, Bruce D. Nearing, Nathan Mewton, Chia Ying Liu, Francis E. Marchlinski, Katherine C. Wu, Larisa G. Tereshchenko, David G. Strauss, Patricia Rizzi, Richard L. Verrier
Publikováno v:
Annals of Noninvasive Electrocardiology. 21:49-59
Background Increased QRS score and wide spatial QRS-T angle are independent predictors of cardiovascular mortality in the general population. Our main objective was to assess whether a QRS score ≥5 and/or QRS-T angle ≥105° enable screening of pa
Autor:
Gustavo J. Volpe, Ronald D. Berger, Peter M. Spooner, Sindhoora Murthy, Larisa G. Tereshchenko, Patricia Rizzi, David G. Strauss, Chia Y. Liu, Nathan Mewton, Peter Kellman, Francis E. Marchlinski, Joao A.C. Lima
Publikováno v:
International Journal of Cardiology. 172:196-201
It is known that expanded epicardial fat is associated with atrial fibrillation (AF). However, infiltrated intraatrial fat has not been previously quantified in individuals at risk as determined by the ARIC AF risk score.Patients in sinus rhythm (N=9
Autor:
David G. Strauss, Bruce D. Nearing, Katherine C. Wu, Richard L. Verrier, Larisa G. Tereshchenko, Christopher Cox, Nathan Mewton, Tony Killian, Raimond L. Winslow, John Moxley, Francis E. Marchlinski, Joao A.C. Lima, Peter M. Spooner
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 6:1156-1162
Background— Current methods to identify patients at higher risk for sudden cardiac death, primarily left ventricular ejection fraction ≤35%, miss ≈80% of patients who die suddenly. We tested the hypothesis that patients with elevated QRS-scores
Autor:
B S Sindhoora Murthy, Ronald D. Berger, Nathan Mewton, Larisa G. Tereshchenko, Peter Kellman, Patricia Rizzi, Joao A.C. Lima, David G. Strauss, Gustavo Jardim Volpe, Chia Y. Liu, Peter M. Spooner, Francis E. Marchlinski
Publikováno v:
Annals of Noninvasive Electrocardiology. 19:114-121
Background Although atrial fibrillation (AF) triggers are known, the underlying AF substrate is less well understood. The goal of our study was to explore correlations between electrophysiological and structural characteristics of atria in patients w
Autor:
Sumeet S. Chugh, Jo Navarro, Audrey Evanado, Carmen Teodorescu, Karen Gunson, Adriana Huertas-Vazquez, Kyndaron Reinier, Jonathan Jui, Peter M. Spooner, Moritz F. Sinner, Stefan Kääb, Shawn K. Westaway
Publikováno v:
Circulation: Cardiovascular Genetics. 4:397-402
Background— Recent evidence suggests a genetic component for sudden cardiac death (SCD) in subjects with coronary artery disease (CAD). We conducted a systematic candidate-gene approach using haplotype-tagging single nucleotide polymorphisms (htSNP
Autor:
Peter M. Spooner
Publikováno v:
Journal of Cardiovascular Electrophysiology. 20:585-596
This perspective considers progress in understanding how genetic influences modulate susceptibility to lethal ventricular arrhythmias in cardiac patients and the population at large, as opposed to those with rare inherited arrhythmic conditions, such
Autor:
Peter M. Spooner, David A. Lathrop
Publikováno v:
Journal of Cardiovascular Electrophysiology. 12:841-844
On the Neural Connection Discoveries concerning cardiac neural-electrical modulation and local neural remodeling provide powerful new approaches for the development of novel antiarrhythmic strategies. This “view” of developments in this emerging
Autor:
Russell P. Tracy, Douglas P. Zipes, James E. Muller, Emelia J. Benjamin, Xavier Jouven, Christine M. Albert, Peter J. Schwartz, David S. Siscovick, Robin Boineau, Wojciech Zareba, Peter M. Spooner, Robert C. Elston, Eduardo Marbán, Lewis H. Kuller, Jean W. MacCluer, Alfred L. George
Publikováno v:
Circulation. 103:2361-2364
Abstract —Malignant ventricular arrhythmias are the leading mechanism of death in patients with acute and chronic cardiac pathologies. The extent to which inherited mutations and polymorphic variation in genes determining arrhythmogenic mechanisms