Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peter M. Paciorek"'
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:454-460
Tumor necrosis factor (TNF) is an inflammatory cytokine produced by many cell types which may contribute to the pathophysiology of a variety of lung diseases. In this study we have used Ro 45-2081 (a soluble receptor composed of the human p55 TNF rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498f860312671a82bc6d896236f1d710
https://doi.org/10.1165/ajrcmb.14.5.8624250
https://doi.org/10.1165/ajrcmb.14.5.8624250
Autor:
Michael Brewster, Peter M. Paciorek, John F. Waterfall, Jennifer C. McKean, Kevin L. Wilson, Paul R. Gater
Publikováno v:
European Journal of Pharmacology. 238:59-64
This study compares the effects of two K(+0-channel openers, Ro 31-6930 and BRL 38227, on cholinergically-evoked contraction of guinea-pig airways to examine whether either compound acts through prejunctional inhibition of the release of acetylcholin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa708d4bb12b5d70529b3bbdaf5b42da
https://doi.org/10.1016/0014-2999(93)90505-c
https://doi.org/10.1016/0014-2999(93)90505-c
Autor:
J.C. Taylor, A.M. Spence, P.R. Gater, D.T. Burden, Peter M. Paciorek, John F. Waterfall, Y.M. Hawthorne
Publikováno v:
Pulmonary pharmacology. 4(4)
Ro 31-6930, a potent smooth muscle relaxant from the novel class of potassium channel openers, has been compared with BRL 38227, salmeterol and theophylline in a range of models of airway function. Ro 31-6930 relaxed isolated tracheal muscle from sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd34b76de838d666b1176031f941966
https://pubmed.ncbi.nlm.nih.gov/1806135
https://pubmed.ncbi.nlm.nih.gov/1806135
Publikováno v:
European journal of pharmacology. 185(1)
The regional haemodynamic profiles of Ro 31-6930, cromakalim and nifedipine were compared using pulsed Doppler flowmetry in the anaesthetised rat. In order of potency, Ro 31-6930 (0.1-300 micrograms/kg), cromakalim (1-300 micrograms/kg) and nifedipin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2b8c6c10a0c73aa6bdb9cec9ec702a
https://pubmed.ncbi.nlm.nih.gov/2226633
https://pubmed.ncbi.nlm.nih.gov/2226633
Publikováno v:
Biochemical Pharmacology. 32:877-881
Meptazinol elevated mean arterial pressure in rats which had been treated with endotoxin. The drug also reduced the titer of circulating lysosomal enzymes. This effect was secondary to the restoration of mean arterial pressure (MAP). In vitro, meptaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d9b627ce20c8fe7d656f84a0428dd7b
https://doi.org/10.1016/0006-2952(83)90591-9
https://doi.org/10.1016/0006-2952(83)90591-9
Publikováno v:
Biochemical pharmacology. 30(12)
The level of adenosinetriphosphate (ATP) in the cerebral cortex of rats was shown to be decreased on exposure to hypoxic conditions (4% O 2 , 0.05% CO 2 , 95.95% N 2 ). This effect of hypoxia was markedly inhibited by subhypotensive doses of indorami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f241345023ae0fe4b69c1653e2bf6f2
https://pubmed.ncbi.nlm.nih.gov/7271848
https://pubmed.ncbi.nlm.nih.gov/7271848
Publikováno v:
European journal of pharmacology. 110(2)
The selectivities of WY26392 and yohimbine for prejunctional alpha 2-adrenoceptors have been evaluated in the anaesthetised dog. Clonidine inhibited the tachycardia evoked by cardiac sympathetic nerve stimulation, WY26392 and yohimbine reversed this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5db9513383eb256c5523275e9bc677c
https://pubmed.ncbi.nlm.nih.gov/2859215
https://pubmed.ncbi.nlm.nih.gov/2859215