Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Peter M. Lackie"'
Autor:
Philip J. Basford, Orestis L. Katsamenis, Richard P. Boardman, Stephanie K. Robinson, Peter M. Lackie, Elena Konstantinopoulou, J. Arjuna Ratnayaka, Anton Page, Gareth J. Thomas, Patricia M. Goggin, Ian Sinclair, Simon J. Cox, Philipp Schneider
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background The University of Southampton, in collaboration with the University Hospital Southampton (UHS) NHS Foundation Trust and industrial partners, has been at the forefront of developing three-dimensional (3D) imaging workflows using X-ray micro
Externí odkaz:
https://doaj.org/article/b0eca1b24de04d559f74a9f42a48df65
Autor:
Philip J. Basford, Orestis L. Katsamenis, Richard P. Boardman, Stephanie K. Robinson, Peter M. Lackie, Elena Konstantinopoulou, J. Arjuna Ratnayaka, Anton Page, Gareth J. Thomas, Patricia M. Goggin, Ian Sinclair, Simon J. Cox, Philipp Schneider
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: The University of Southampton, in collaboration with the University Hospital Southampton (UHS) NHS Foundation Trust and industrial partners, has been at the forefront of developing three-dimensional (3D) imaging workflows using X-ray micr
Externí odkaz:
https://doaj.org/article/19ceba3d86a1405fb292bd21883dfb12
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Lung lymphatics maintain fluid homoeostasis by providing a drainage system that returns fluid, cells and metabolites to the circulatory system. The 3D structure of the human pulmonary lymphatic network is essential to lung function, but it i
Externí odkaz:
https://doaj.org/article/b58fc3cc5e714adfbe6a2de50ebebe48
Autor:
Janice L. Coles, James Thompson, Katie L. Horton, Robert A. Hirst, Paul Griffin, Gwyneth M. Williams, Patricia Goggin, Regan Doherty, Peter M. Lackie, Amanda Harris, Woolf T. Walker, Christopher O’Callaghan, Claire Hogg, Jane S. Lucas, Cornelia Blume, Claire L. Jackson
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 11, p 3753 (2020)
Air–liquid interface (ALI) culture of nasal epithelial cells is a valuable tool in the diagnosis and research of primary ciliary dyskinesia (PCD). Ex vivo samples often display secondary dyskinesia from cell damage during sampling, infection or inf
Externí odkaz:
https://doaj.org/article/a1cb524f765645499536d8b07971fc37
Autor:
Beata Narożna, Wojciech Langwiński, Claire Jackson, Peter M. Lackie, John W. Holloway, Zuzanna Stachowiak, Monika Dmitrzak-Węglarz, Aleksandra Szczepankiewicz
Publikováno v:
International Journal of Genomics, Vol 2018 (2018)
Purpose. Airway epithelium acts as a protective barrier against the particles from the inhaled air. Damage to the epithelium may result in loss of the barrier function. Epithelial repair in response to injury requires complex mechanisms, such as micr
Externí odkaz:
https://doaj.org/article/d7ca349dfd0c46b5a532d5222b391aba
Autor:
Pierre Thibault, Vincent Fernandez, Vartan Kurtcuoglu, Marie-Christine Zdora, Matthew J. Lawson, Peter M. Lackie, Alexander Rack, Christoph Rau, Willy Kuo, Hans Deyhle, Orestis L. Katsamenis, Margie P. Olbinado, Joan Vila-Comamala, Franz Pfeiffer, Irene Zanette
Publikováno v:
'Optica ', vol: 7, pages: 1221-1227 (2020)
High-contrast, high-resolution imaging of biomedical specimens is indispensable for studying organ function and pathologies. Conventional histology, the gold standard for soft-tissue visualization, is limited by its anisotropic spatial resolution, el
Autor:
Peter M. Lackie, Matthew J. Lawson, Philipp Schneider, David S. Chatelet, Oliver Larkin, Ian Haig, Aiman Alzetani, Orestis L. Katsamenis, Jane Warner
Publikováno v:
Royal Society Open Science
Royal Society Open Science, Vol 8, Iss 11 (2021)
Royal Society Open Science, Vol 8, Iss 11 (2021)
Micro-computed tomography (µCT) provides non-destructive three-dimensional (3D) imaging of soft tissue microstructures. Specific features in µCT images can be identified using correlated two-dimensional (2D) histology images allowing manual segment
Autor:
Oliver J. Larkin, Philipp Schneider, Jane Warner, Peter M. Lackie, Michael Olding, Orestis L. Katsamenis, Bennie Smit, Ian Haig, Matthew J. Lawson
Publikováno v:
14.01 - Imaging.
Micro-computed tomography (µCT) is a non-destructive 3D imaging technique used to map tissue microstructure at typical resolutions of 1-10 µm. Correlated with 2D immunofluorescence (IF) microscopy pathophysiologically relevant cells can be identifi
Multiplexed mRNA Sensing and Combinatorial-Targeted Drug Delivery Using DNA-Gold Nanoparticle Dimers
Autor:
Antonios G. Kanaras, Davide Giust, Afaf H. El-Sagheer, Otto L. Muskens, Tom Brown, Peter M. Lackie, Maria Eleni Kyriazi
Publikováno v:
ACS Nano. 12:3333-3340
The design of nanoparticulate systems which can perform multiple synergistic functions in cells with high specificity and selectivity is of great importance in applications. Here we combine recent advances in DNA-gold nanoparticle self-assembly and s
Autor:
Aleksandra Szczepankiewicz, Peter M. Lackie, Wojciech Langwiński, Beata Narozna, John W. Holloway
Publikováno v:
Journal of Applied Genetics. 58:205-212
Respiratory epithelium is a highly integrated structure that efficiently protects lungs from extrinsic irritants thanks to rapid repair of the wound. The repair is a complex process that requires coordinated expression of networks of genes. Plausible