Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Peter M. Kang"'
A Systematic Review on Advances in Management of Oxidative Stress-Associated Cardiovascular Diseases
Autor:
Soyeon Jin, Peter M. Kang
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 923 (2024)
Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension. This systematic review aims to integrate most relevant studies
Externí odkaz:
https://doaj.org/article/26ca00364be14453bbb8427d7a6f4426
Autor:
Santosh A. Khedkar, Mohammed A. Samad, Sangita Choudhury, Ji Yoo Lee, Dongsheng Zhang, Ravi I. Thadhani, S. Ananth Karumanchi, Alan C. Rigby, Peter M. Kang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Vitamin D regulates many biological processes, but its clinical utility is limited by its hypercalcemic effect. Using a virtual screening platform to search novel chemical probes that activate the vitamin D signaling, we report discovery of
Externí odkaz:
https://doaj.org/article/853bea727f7e4295a02ec950760e473a
Autor:
Wenjun Wang, Peter M. Kang
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1292 (2020)
Oxidative stress plays a key role in many physiological and pathological conditions. The intracellular oxidative homeostasis is tightly regulated by the reactive oxygen species production and the intracellular defense mechanisms. Increased oxidative
Externí odkaz:
https://doaj.org/article/cc520e976c304304be6d23c14a0e626c
Autor:
Lei Yuan, Gary C. Chan, David Beeler, Lauren Janes, Katherine C. Spokes, Harita Dharaneeswaran, Anahita Mojiri, William J. Adams, Tracey Sciuto, Guillermo Garcia-Cardeña, Grietje Molema, Peter M. Kang, Nadia Jahroudi, Philip A. Marsden, Ann Dvorak, Erzsébet Ravasz Regan, William C. Aird
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Spontaneous phenotypic heterogeneity confers a population-level advantage to cells that are exposed to fluctuating environments. Here the authors show that the endothelium of some organs displays a dynamic mosaicism in expression of Von Willebrand fa
Externí odkaz:
https://doaj.org/article/6ed9333a2a8b469cb9f3182d7d55819d
Autor:
Shi Su, Peter M. Kang
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 837 (2020)
Nanotechnologies have attracted increasing attention in their application in medicine, especially in the development of new drug delivery systems. With the help of nano-sized carriers, drugs can reach specific diseased areas, prolonging therapeutic e
Externí odkaz:
https://doaj.org/article/8969b22ea8dc4d39ad2b64484e47f6bb
Autor:
Shi Su, Peter M. Kang
Publikováno v:
Nanomaterials, Vol 10, Iss 4, p 656 (2020)
Background: Nanomedicine is a field of science that uses nanoscale materials for the diagnosis and treatment of human disease. It has emerged as an important aspect of the therapeutics, but at the same time, also raises concerns regarding the safety
Externí odkaz:
https://doaj.org/article/a26e6c0d2e8d41f98e47ae5acc62a987
Autor:
Soochan Bae, Minhyung Park, Changsun Kang, Serkan Dilmen, Tae Hi Kang, Dong Goo Kang, Qingen Ke, Seung Uk Lee, Dongwon Lee, Peter M. Kang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)
BackgroundDuring myocardial ischemia/reperfusion (I/R), a large amount of reactive oxygen species (ROS) is produced. In particular, overproduction of hydrogen peroxide (H2O2) is considered to be a main cause of I/R‐mediated tissue damage. We genera
Externí odkaz:
https://doaj.org/article/b0fcf4b017964582b85516344764ba7e
Publikováno v:
International Journal of Mental Health Promotion. 23:303-317
The extent of viral spread and strategies in dealing with the COVID-19 pandemic have been different in each country. There are overall increased mental health concerns in many countries but it is unclear what the general public individuals who do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::212e5f4583f61e25e3c88b8a927ba6d3
https://doi.org/10.32604/ijmhp.2021.016470
https://doi.org/10.32604/ijmhp.2021.016470
Autor:
Shi Su, Peter M. Kang, Ruijian Li, Dongwon Lee, Qingen Ke, Ye Eun Koo, Changsun Kang, Chul-Gyu Song, Chloe Ryu, Soochan Bae, Sang Jae Rhee
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 26:279-288
Mortality and morbidity after cardiac arrest remain high due to ischemia/reperfusion (I/R) injury causing multi-organ damages, even after successful return of spontaneous circulation. We previously generated H2O2-activatable antioxidant nanoparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b859247bf55a53a5165ddecf708a572a
https://doi.org/10.1177/1074248420969571
https://doi.org/10.1177/1074248420969571
Autor:
Brandy Houser, Ian Morrison, Peter M. Kang, Jake Reder, Edward Van Keuren, Koichiro Minami, Abdala Elkhal, Hirofumi Uehara, Jasper Iske, Michael W. Fanger, Astrid Wiens, Chen Zhao, Haruhito Azuma, Dongwon Lee, Stefan G. Tullius, Soochan Bae
Publikováno v:
Am J Transplant
Inflammatory responses associated with ischemia/reperfusion injury (IRI) play a central role in alloimmunity and transplant outcomes. A key event driving these inflammatory responses is the burst of reactive oxygen species, with hydrogen peroxide (H(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2325521564d916ae327cf95105ab2b0b
https://doi.org/10.1111/ajt.15794
https://doi.org/10.1111/ajt.15794