Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter M. Jobst"'
Autor:
Connie L. Heffron, Karen Hall, Eda Rogers, Paul B. Siegel, Shannon R. Matzinger, Xiang-Jin Meng, Peter M. Jobst, Danielle M. Yugo, Stephanie Michelle Todd, Michaela Jones, Charles S. Kirby, Elena Mircoff, Robert J. Etches, Irene Ngo, Tanya LeRoith, Scott P. Kenney, Frank William Pierson
Publikováno v:
Journal of Medical Virology. 91:1960-1969
Hepatitis E is an important global disease, causing outbreaks of acute hepatitis in many developing countries and sporadic cases in industrialized countries. Hepatitis E virus (HEV) infection typically causes self-limiting acute hepatitis but can als
Autor:
Jacob Kocher, Lijuan Yuan, David Ayares, Tammy Bui, Ke Wen, Peter M. Jobst, Mariah Weiss, Sherrie Clark-Deener, Suyapa Ball, Xingdong Yang, Guohua Li, Todd Vaught, Jagdeece Ramsoondar
Publikováno v:
Viral Immunology. 29:112-127
Genetically modified pigs have become available recently. In this study, we established the gnotobiotic pig model of human rotavirus (HRV) infection using cloned pigs with homozygous disruption in the gene encoding immunoglobulin heavy chain (HCKO),
Autor:
Hayden Bickerton, Cassie Boyd, Benoit Chassaing, Kathryn A. Eaton, Torunn Forberg, Andrew T. Gewirtz, Peter M. Jobst, George Langan, Kathryn Milligan-Myhre, Roger P. Orcutt, Billie J. Parsons, Richard J. Rahija, Trenton R. Schoeb, Stacey Sinclair, Alton G. Swennes, Betty Theriault, Chriss Vowles, Mariah Weiss, Lijuan Yuan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22fed52b9954bfc29c0fd2b6afc58400
https://doi.org/10.1016/b978-0-12-804561-9.01002-1
https://doi.org/10.1016/b978-0-12-804561-9.01002-1
Gnotobiotic pigs have been increasingly recognized as a very valuable animal model system for the studies of microbiology and immunology. The number of functional gnotobiotic pig facilities remains low, however, mainly because of the technical comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e9578e0e98440feea3383c628c1e047
https://doi.org/10.1016/b978-0-12-804561-9.00005-0
https://doi.org/10.1016/b978-0-12-804561-9.00005-0
Autor:
A. Vance, Todd Vaught, Jeff A. Monahan, Irina A. Polejaeva, Peter M. Jobst, Y. Dai, Jeremy Boone, M. Mendicino, Carol Phelps, Kevin D. Wells, David Ayares, LeRoith T, J. Ramsoondar, Xiu-Zhu Sun, Dandro A, Suyapa Ball, John E. Butler, Nancy Wertz, Bergman Z, S. Chen
Publikováno v:
Transgenic Research
A poly(A)-trap gene targeting strategy was used to disrupt the single functional heavy chain (HC) joining region (J(H)) of swine in primary fibroblasts. Genetically modified piglets were then generated via somatic cell nuclear transfer (SCNT) and bre
Autor:
Peter M. Jobst, Kenneth J. McCreath, Shu-Hung Chen, Alan Colman, Carol Phelps, Ashley E. Lamborn, Kevin D. Wells, Todd Vaught, Suyapa Ball, Jeremy Boone, Jeff A. Monahan, Irina A. Polejaeva, Yifan Dai, Jamie L. Cowell-Lucero, David Ayares
Publikováno v:
Nature Biotechnology. 20:251-255
Galactose-alpha1,3-galactose (alpha1,3Gal) is the major xenoantigen causing hyperacute rejection in pig-to-human xenotransplantation. Disruption of the gene encoding pig alpha1,3-galactosyltransferase (alpha1,3GT) by homologous recombination is a mea
Autor:
Peter M. Jobst, David Ayares, J. Ramsoondar, Suyapa Ball, Y. Dai, A. Vance, M. Mendicino, Nancy Wertz, Carol Phelps, Dandro A, Todd Vaught, Jeremy Boone, S. Chen, Kevin D. Wells, Jeff A. Monahan, John E. Butler, Irina A. Polejaeva
Publikováno v:
Transgenic research. 20(3)
Inactivation of the endogenous pig immunoglobulin (Ig) loci, and replacement with their human counterparts, would produce animals that could alleviate both the supply and specificity issues of therapeutic human polyclonal antibodies (PAbs). Platform
Autor:
Peter M. Jobst, Michael Mendicino, Kevin D. Wells, Jeff A. Monahan, David Ayares, Suyapa Ball, Amy M. Vance, Todd Vaught, Jagdeece Ramsoondar, Jane Duncan
Publikováno v:
Xenotransplantation. 16(3)
Background: The presence of multiple copies of porcine endogenous retrovirus (PERV) within the pig genome, and the demonstration that replication competent PERV, that infect human cells in culture, can be isolated from pig cells, directly impacts the
Autor:
Todd Vaught, Peter M. Jobst, Angelika Schnieke, Laura Robertson, Shu-Hung Chen, Ashley E. Lamborn, Elizabeth Emslie, Alan Colman, Jeremy Boone, Jeff A. Monahan, Irina A. Polejaeva, David Ayares, Yifan Dai
Publikováno v:
Biology of reproduction. 67(5)
The genetic manipulation of donor cells before nuclear transfer (NT) enables prior selection for transgene integration. However, selection for genetically modified cells using antibiotic drugs often results in mixed populations, resulting in a mixtur