Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Peter M. Hwang"'
Autor:
Wenbo He, Ke Wu, Zhenlin Ouyang, Yixin Bai, Wen Luo, Di Wu, Hao An, Yucheng Guo, Min Jiao, Qian Qin, Jiaxin Zhang, Yi Wu, Junjun She, Peter M. Hwang, Fang Zheng, Li Zhu, Yurong Wen
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112781- (2023)
Summary: Type VI secretion system is widely used in Gram-negative bacteria for injecting toxic effectors into neighboring prokaryotic or eukaryotic cells. Various effectors can be loaded onto the T6SS delivery tube via its core components: Hcp, VgrG,
Externí odkaz:
https://doaj.org/article/a825f6f89108470ea065fd8abbd15485
Autor:
Airiss R. Chan, Jan Willem Cohen Tervaert, Desiree Redmond, Elaine Yacyshyn, Giovanni Ferrara, Peter M. Hwang, Mohamed Osman, Robert Gniadecki
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Background/ObjectiveThe most significant adverse events following SARS-CoV-2 vaccination are myocarditis and pericarditis. Myositis and dermatomyositis have been reported following SARS-CoV-2 infection, but vaccine-induced dermatomyositis (DM) has no
Externí odkaz:
https://doaj.org/article/4824cfcea33740e3b804c643d8238980
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Cory S. Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow
Externí odkaz:
https://doaj.org/article/756603ce756d47d9bebb8a3a2a2a53cd
Autor:
Monica X. Li, Shorena Gelozia, Gaddafi I. Danmaliki, Yurong Wen, Philip B. Liu, M. Joanne Lemieux, Frederick G. West, Brian D. Sykes, Peter M. Hwang
Publikováno v:
Biochemistry and Biophysics Reports, Vol 16, Iss , Pp 145-151 (2018)
The compound MCI-154 was previously shown to increase the calcium sensitivity of cardiac muscle contraction. Using solution NMR spectroscopy, we demonstrate that MCI-154 interacts with the calcium-sensing subunit of the cardiac troponin complex, card
Externí odkaz:
https://doaj.org/article/7921eb263864415793b07715535b4a6d
Autor:
Zhenlin Ouyang, Fang Zheng, Li Zhu, Jan Felix, Di Wu, Ke Wu, Irina Gutsche, Yi Wu, Peter M. Hwang, Junjun She, Yurong Wen
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102476- (2021)
Summary: Bacterial two-component regulatory systems are ubiquitous environment-sensing signal transducers involved in pathogenesis and antibiotic resistance. The Acinetobacter baumannii two-component regulatory system AdeRS is made up of a sensor his
Externí odkaz:
https://doaj.org/article/d6d1cfd292b44d089c37fb18f2346f22
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Corey Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Richard Schulz, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1147fd54b772479d3c37403d3f13bf41
https://doi.org/10.1096/fasebj.2022.36.s1.0r342
https://doi.org/10.1096/fasebj.2022.36.s1.0r342
Autor:
Gaddafi I. Danmaliki, Peter M. Hwang
Publikováno v:
Journal of biomolecular NMR. 76(4)
Protein side chain dynamics play a vital role in many biological processes, but differentiating mobile from rigid side chains remains a technical challenge in structural biology. Solution NMR spectroscopy is ideally suited for this but suffers from l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2b1cb46b1763180a6e4e02f89d402b
https://pubmed.ncbi.nlm.nih.gov/35864369
https://pubmed.ncbi.nlm.nih.gov/35864369
Publikováno v:
Biophysical Journal. 122:43a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d54093f6395474d7de3c277b1c95d023
https://doi.org/10.1016/j.bpj.2022.11.443
https://doi.org/10.1016/j.bpj.2022.11.443
Publikováno v:
Circulation. 144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7231f6749d26a641183954c649b35c00
https://doi.org/10.1161/circulationaha.121.055413
https://doi.org/10.1161/circulationaha.121.055413
Autor:
Peter M. Hwang, M. Joanne Lemieux, Keqing Wen, Fang Zheng, Jinhong Zhou, Jared Y Chew, Zhenlin Ouyang, Yurong Wen, Miao Han, Yingmei Pei
Publikováno v:
Nucleic Acids Research
Staphylococcus aureus ArlRS is a key two-component regulatory system necessary for adhesion, biofilm formation, and virulence. The response regulator ArlR consists of a C-terminal DNA-binding effector domain and an N-terminal receiver domain that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f46bb3a57fc28125ea69e942301bf7
https://doi.org/10.1093/nar/gkz891
https://doi.org/10.1093/nar/gkz891