Zobrazeno 1 - 4
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pro vyhledávání: '"Peter M Van Endert"'
Autor:
Peter M Van Endert, Loredana eSaveanu
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Production of MHC I ligands from antigenic proteins generally requires multiple proteolytic events. While the proteolytic steps required for antigen processing in the endogenous pathway are clearly established, persisting gaps of knowledge regarding
Externí odkaz:
https://doaj.org/article/679c2095c24b434ca73c2d9b2fe2c5e3
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Major histocompatibility complex class I (MHC I) molecules are glycoproteins that display peptide epitopes at the cell surface of nucleated cells for recognition by CD8+ T cells. Like other cell surface receptors, MHC class I molecules are continuous
Externí odkaz:
https://doaj.org/article/ffebef1ef3e34da992c49a3660037190
Publikováno v:
Molecular Immunology. 150:20
Cross-presentation of internalized antigens by MHC class I molecules (MHC-I) plays a critical role in priming of cytotoxic T cells recognizing pathogens and tumors. It is thought that peptides derived from cross-presented antigens can be loaded on MH
Publikováno v:
The Journal of Immunology. 202:177.22-177.22
Cross-priming of CD8+ T cells is of critical importance in triggering CD8+ T cell responses against pathogens and tumors. It is commonly thought that conventional type 1 dendritic cells (cDC1) cross-prime with unequalled efficacy, conferred to them b