Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter M Krein"'
Autor:
Lisa M. Hess, Patrick Peterson, Tomoko Sugihara, Naleen Raj Bhandari, Peter M. Krein, Anthony Sireci
Publikováno v:
Cancer Treatment and Research Communications, Vol 37, Iss , Pp 100761- (2023)
Objectives: This study compared outcomes between patients with biomarker-positive advanced/metastatic non-small cell lung cancer (a/mNSCLC) who initiated treatment with targeted therapy versus those who initiated chemotherapy-based treatment and swit
Externí odkaz:
https://doaj.org/article/22a0aa08d379490ebe10a39f872dce36
Autor:
Lisa M. Hess, PhD, Peter M. Krein, PhD, Diane Haldane, MS, Yimei Han, MS, Anthony N. Sireci, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100336- (2022)
Introduction: NSCLC is a solid tumor with a growing number of actionable biomarkers that may inform treatment. Current guidelines recommend a broad, panel-based approach be taken to identify actionable markers. This retrospective study used a deident
Externí odkaz:
https://doaj.org/article/d32e156caf454ecfa2167d39ca22d157
Publikováno v:
Journal of Medical Economics. 26:43-50
This real-world retrospective database study quantified the costs of biomarker testing in a US population of patients with lung or thyroid cancers.The commercial claims IBM Marketscan database, a de-identified real-world dataset, was used to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef9630f7a8153b0857b0c34e9caa5da
https://doi.org/10.1080/13696998.2022.2154479
https://doi.org/10.1080/13696998.2022.2154479
Autor:
Anthony N. Sireci, Peter M. Krein, Lisa M. Hess, Taha Khan, Joanne Willey, Michael Ayars, Kathryn Deyoung, Sandhya Bhaskar, Ganiat Mumuney, Anna Coutinho
Publikováno v:
Clinical Lung Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04262be0258837466f204dbafae4af49
https://doi.org/10.1016/j.cllc.2023.03.002
https://doi.org/10.1016/j.cllc.2023.03.002
Autor:
Naleen Raj Bhandari, Lisa M Hess, Rohan C Parikh, Anthony N Sireci, Peter M Krein, James A Kaye
Publikováno v:
Personalized Medicine.
Aim: To describe real-world testing patterns for RET in US patients with advanced/metastatic medullary thyroid cancer and determine consistency of real-world testing practices with national guidelines. Materials & methods: The authors performed a ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27251595b9e349e83cdd379db4cdb7f2
https://doi.org/10.2217/pme-2022-0050
https://doi.org/10.2217/pme-2022-0050
Autor:
Jesus Rivera-Nieves, L. Terry Spencer, Farshid N. Rouhani, Mark L. Brantly, Peter M. Krein, Gregorino Paone
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L514-L520
Individuals with α1-antitrypsin (α1-AT) deficiency are at risk for early-onset destructive lung disease as a result of insufficient lower respiratory tract α1-AT and an increased burden of neutrophil products such as elastase. Human neutrophil pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809501c6f751d410fe472891b3bd6ffa
https://doi.org/10.1152/ajplung.00099.2003
https://doi.org/10.1152/ajplung.00099.2003
Autor:
Peter J. B. Sabatini, Francis H. Y. Green, Brent W. Winston, William Tinmouth, Peter M. Krein
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 167:83-90
Insulin-like growth factor-I (IGF-I) is elevated in human fibrotic lung diseases and in animal models of pulmonary fibrosis, implicating IGF-I in the pathogenesis of fibrotic lung disease. We questioned whether IGF-I protein levels were enhanced in f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f720d149004e4510e1b348fa097909e
https://doi.org/10.1164/rccm.2201012
https://doi.org/10.1164/rccm.2201012
Autor:
Brent W. Winston, Peter M. Krein
Publikováno v:
Chest. 122:289S-293S
Idiopathic pulmonary fibrosis (IPF) is a lung disease that is characterized by epithelial cell damage and areas of denuded basement membrane resulting in inflammation, fibroblast proliferation, excessive extracellular matrix (ECM) deposition, and rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdc2250800fe9c4e1c96d309b9033f9
https://doi.org/10.1378/chest.122.6_suppl.289s
https://doi.org/10.1378/chest.122.6_suppl.289s
Autor:
Brent W. Winston, Graciela Andonegui, Connie Mowat, Peter M. Krein, Ronald Brisebois, Caroline Léger, Christopher J. Doig, Francis H. Y. Green
Publikováno v:
Physiological Reports
Insulin‐Like Growth Factor I (IGF‐I) has been identified in the lungs of individuals with fibrotic lung diseases. In a previous retrospective study, we showed enhanced IGF‐I immunoreactivity in individuals with fibroproliferative acute respirat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95628e2847e941963627af8bc4b04110
http://europepmc.org/articles/PMC4255805
http://europepmc.org/articles/PMC4255805
Publikováno v:
European Journal of Immunology. 31:3676-3686
Complement factor B (Bf) is involved in the activation of the alternative complement cascade. Bf is induced by IFN-gamma; however, the mechanisms of Bf gene regulation have not been well characterized in general, and not in macrophages specifically.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79aceebc1483279608ec1a8bbdfcaf24
https://doi.org/10.1002/1521-4141(200112)31:12<3676::aid-immu3676>3.0.co
https://doi.org/10.1002/1521-4141(200112)31:12<3676::aid-immu3676>3.0.co