Výsledky vyhledávání - "Peter Lundholm"

Autor: Peter Lundholm, Ann-Charlotte Leandersson, G. Bratt, Britta Wahren, Birger Christensson, Eric Sandström

Publikováno v: Virus Research. 82:141-145

This is a demonstration of immune activation by delivery of genetic vaccines in human mucosa. We analyzed the local and systemic responses in HIV-1 infected individuals following intraoral jet-injections of HIV-1 DNA constructs encoding the nef, rev,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a015beb1c294a940fc49a2e0747528d7
https://doi.org/10.1016/s0168-1702(01)00396-3

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Induction of mucosal IgA by a novel jet delivery technique for HIV-1 DNA

Autor: Erik Lucht, Peter Lundholm, Britta Wahren, Yusuke Asakura, Jorma Hinkula

Publikováno v: Vaccine. 17:2036-2042

Novel ways of delivering plasmid DNA to elicit humoral IgA, IgG and cell-mediated immune responses in mice were investigated. Intraoral administration of DNA in the cheek, using a jet immunization technique, elicited the highest IgA mucosal responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ce1eb18226163fa86e1bdf30aea855
https://doi.org/10.1016/s0264-410x(98)00404-6

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Recognition of prominent viral epitopes induced by immunization with human immunodeficiency virus type 1 regulatory genes

Autor: Jorma Hinkula, C Svanholm, Maria Brytting, H Glaser, Peter Lundholm, K Okuda, Stefan Schwartz, Birgit Kohleisen, Gunnel Engström, V Erfle, Hans Wigzell, Reinhold Benthin, Britta Wahren, G. Sutter

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Mice immunized with the regulatory genes nef, rev, and tat from human immunodeficiency virus type 1 developed both humoral and cellular immune responses to the gene products Nef, Rev, and Tat. This study demonstrates that it is feasible to induce imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589483fe6f4fc0c857e1328d8866fa64
https://doi.org/10.1128/jvi.71.7.5528-5539.1997

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Nucleic acid vaccination with HIV regulatory genes: a combination of HIV-1 genes in separate plasmids induces strong immune responses

Autor: Jorma Hinkula, Peter Lundholm, Britta Wahren

Publikováno v: Vaccine. 15:874-878

The concept of combining several genes in order to immunize against a microbial agent has been tested. We selected human immunodeficiency virus (HIV) genes that individually have been shown to mediate immune responses against HIV proteins. These prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbb56aa7c7191c7d94323dfc8b2ef1b
https://doi.org/10.1016/s0264-410x(96)00257-5

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Locations of antibody binding sites within conserved regions of the hepatitis C virus core protein

Autor: Peter Lundholm, Pauls Pumpen, Matti Sällberg, Zhu-Xu Zhang, Britta Wahren, Lars O. Magnius, Indulis Gusars, Ulla Rudén

Publikováno v: Journal of Medical Virology. 43:62-68

The binding sites for human antibodies recognising antigenic domains within the hepatitis C virus (HCV) core protein were analyzed using synthetic peptides. Omission peptide analogues where a pair of residues was sequentially omitted were produced co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7bea81ffc5f2053d62ce5f3d744a78
https://doi.org/10.1002/jmv.1890430112

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Genetic immunization with multiple HIV-1 genes provides protection against HIV-1/MuLV pseudovirus challenge in vivo

Autor: Kenji Okuda, Jorma Hinkula, Peter Lundholm, Britta Wahren, Erik Rollman, Reinhold Benthin

Publikováno v: Cells, tissues, organs. 177(3)

Superinfection by HIV-1 of a cell line containing the complete murine leukemia virus (MuLV) genome was shown to give rise to pseudotyped HIV-1/MuLV. Such superinfection was successful with certain strains of HIV-1 subtypes A–D. Primary spleen cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9a6c6e736b6e97cee15dc94d8e2cd2
https://pubmed.ncbi.nlm.nih.gov/15388991

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Designing tangible interfaces for children's collaboration

Autor: Fredrik Nilbrink, Anna Persson, Kent Lindbergh, Diana Africano, Sara Berg, Peter Lundholm

Publikováno v: CHI Extended Abstracts

This paper presents the development of a design concept for an interactive play system and learning tool for children. The concept was illustrated with Ely the Explorer, an accessible and robust multi-user unit, set of tangible tools, and software ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::112aba83a8a28a47fb495eb18daa01ca
https://doi.org/10.1145/985921.985945

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Ely the explorer

Autor: Kent Lindbergh, Fredrik Nilbrink, Staffan Eriksson, Diana Africano, Peter Lundholm

Publikováno v: IDC

This paper briefly presents a design concept for an interactive play system and learning tool for young children. In the search for more intuitive user-interfaces appropriate for children, we have proposed a system featuring a set of physical and vir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90c682c09d95fb7a7cfbe6f0617ae02a
https://doi.org/10.1145/953536.953559

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