Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Peter Loidl"'
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266196 (2022)
Retinoblastoma like protein-2 (Rbl2) is functionally regulated by phosphorylation and acetylation. Previously, we demonstrated that lysine K1083 (K1079 in human Rbl2) is a potential target for acetylation but its functional role remains elusive. We i
Externí odkaz:
https://doaj.org/article/30663f063e0545118b46bffc3643f2af
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46174 (2012)
The retinoblastoma protein (pRb) and the related proteins Rb2/p130 and 107 represent the "pocket protein" family of cell cycle regulators. A key function of these proteins is the cell cycle dependent modulation of E2F-regulated genes. The biological
Externí odkaz:
https://doaj.org/article/20d8eb72a2fc4667912bcbc964f99ef0
Autor:
Markus Lechner, Alois Loidl, Florian Schwarze, Taras Stasyk, Joachim Meraner, A Laich, Peter Loidl
Publikováno v:
Oncogene
The retinoblastoma protein (pRb) and the pRb-related proteins, p130 and p107, form the 'pocket protein' family of cell cycle regulatory factors. A well characterized function of these proteins is the cell cycle-dependent regulation of E2F-responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850d4fd7da54e3ebb41b56b8eaa80636
http://europepmc.org/articles/PMC3007177
http://europepmc.org/articles/PMC3007177
Autor:
Florian Jesacher, Florian Schwarze, Markus Lechner, Roland Gander, Peter Loidl, Joachim Meraner
Publikováno v:
Cell Biology International. 32:1073-1080
Ribosome biogenesis and ribosomal DNA transcription are closely correlated with the growth and proliferation of cells, with these processes being under tight epigenetic control. We have investigated the effect of ectopically expressed murine HDAC1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e4400f6d59fe525ee79427cf662db9
https://doi.org/10.1016/j.cellbi.2008.04.018
https://doi.org/10.1016/j.cellbi.2008.04.018
Publikováno v:
Fems Microbiology Reviews
The readout of the genetic information of eukaryotic organisms is significantly regulated by modifications of DNA and chromatin proteins. Chromatin alterations induce genome-wide and local changes in gene expression and affect a variety of processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27097c0f111fad20b264bfb80208f0f2
https://doi.org/10.1111/j.1574-6976.2007.00100.x
https://doi.org/10.1111/j.1574-6976.2007.00100.x
Autor:
Stefan Graessle, Patrick Trojer, Gerald Brosch, Peter Loidl, Florentine Marx, Martin Tribus, Hubertus Haas, Johannes Galehr
Publikováno v:
Eukaryotic Cell. 4:1736-1745
Histone deacetylases (HDACs) catalyze the removal of acetyl groups from the -amino group of distinct lysine residues in the amino-terminal tail of core histones. Since the acetylation status of core histones plays a crucial role in fundamental proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ba4b7258c0ce57df64e4ca6bf598d4
https://doi.org/10.1128/ec.4.10.1736-1745.2005
https://doi.org/10.1128/ec.4.10.1736-1745.2005
Autor:
Dennis Wegener, Daniel Riester, Andreas Schwienhorst, Rüdiger Dietrich, Peter Loidl, Olwen M Birch, Milena Ninkovic, Thomas Zimmermann, Christine Dr. Bernegger, Christian Hildmann
Publikováno v:
Journal of Bacteriology. 186:2328-2339
The full-length gene encoding the histone deacetylase (HDAC)-like amidohydrolase (HDAH) from Bordetella or Alcaligenes ( Bordetella/Alcaligenes ) strain FB188 (DSM 11172) was cloned using degenerate primer PCR combined with inverse-PCR techniques and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee611731e04de27e85f69f46e29f7113
https://doi.org/10.1128/jb.186.8.2328-2339.2004
https://doi.org/10.1128/jb.186.8.2328-2339.2004
Autor:
Roberto Scatena, Antonello Mai, Gunther Brosch, Sergio Valente, Fredrik Jesacher, Ilaria Cerbara, Patrizia Bottoni, Rino Ragno, Peter Loidl, Silvio Massa
Publikováno v:
Journal of Medicinal Chemistry. 47:1351-1359
Aroyl-pyrrole-hydroxy-amides (APHAs) are a new class of synthetic HDAC inhibitors recently described by us. Through three different docking procedures we designed, synthesized, and tested two new isomers of APHA lead compound 3-(4-benzoyl-1-methyl-1H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145c03e03182cf2e85b49e7ed12df248
https://doi.org/10.1021/jm031036f
https://doi.org/10.1021/jm031036f
Autor:
Peter Loidl
Publikováno v:
Trends in Plant Science. 9:84-90
The genome contains all the information needed to build an organism. However, during differentiation and development, additional epigenetic information determines the functional state of cells and tissues. This epigenetic information can be introduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab66398f81dbbf06a3c8e90489c56ca8
https://doi.org/10.1016/j.tplants.2003.12.007
https://doi.org/10.1016/j.tplants.2003.12.007
Autor:
Ilaria Cerbara, Roberto Scatena, Gunther Brosch, Rino Ragno, Patrizia Bottoni, Antonello Mai, Peter Loidl, Sergio Valente, Silvio Massa
Publikováno v:
Journal of Medicinal Chemistry. 47:1098-1109
Previous SAR studies (Part 1: Mai, A.; et al. J. Med. Chem. 2003, 46, 512−524) performed on some portions (pyrrole-C4, pyrrole-N1, and hydroxamate group) of 3-(4-benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamide (1a) highlighted its 4-phenyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c1d3f6e9fb77c56ae083eb2154621a9
https://doi.org/10.1021/jm030990+
https://doi.org/10.1021/jm030990+