Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS): protocol for a randomised, controlled trial – surgery as first-line treatment

Autor: Najib Rahman, Babu Naidu, Eihab O Bedawi, Zaigham Saghir, Uffe Bodtger, Bo Martin Bibby, Christian B Laursen, Thomas Decker Christensen, Morten Bendixen, Søren Helbo Skaarup, Jens-Ulrik Jensen, Rene Horsleben Petersen, Merete Christensen, Peter Licht, Kirsten Neckelmann, Lars B Møller, Morten Hornemann Borg, Sten Langfeldt, Stefan M W Harders

Publikováno v: BMJ Open, Vol 12, Iss 3 (2022)

Introduction Pleural empyema is a frequent disease with a high morbidity and mortality. Current standard treatment includes antibiotics and thoracic ultrasound (TUS)-guided pigtail drainage. Simultaneously with drainage, an intrapleural fibrinolyticu

Externí odkaz: https://doaj.org/article/4d0488125e834a18b61c640fb2130ea8

Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS):protocol for a randomised, controlled trial - surgery as first-line treatment

Autor: Thomas Decker Christensen, Morten Bendixen, Søren Helbo Skaarup, Jens-Ulrik Jensen, Rene Horsleben Petersen, Merete Christensen, Peter Licht, Kirsten Neckelmann, Bo Martin Bibby, Lars B Møller, Uffe Bodtger, Morten Hornemann Borg, Zaigham Saghir, Sten Langfeldt, Stefan M W Harders, Eihab O Bedawi, Babu Naidu, Najib Rahman, Christian B Laursen

Publikováno v: Christensen, T D, Bendixen, M, Skaarup, S H, Jensen, J-U, Petersen, R H, Christensen, M, Licht, P, Neckelmann, K, Bibby, B M, Møller, L B, Bodtger, U, Borg, M H, Saghir, Z, Langfeldt, S, Harders, S M W, Bedawi, E O, Naidu, B, Rahman, N & Laursen, C B 2022, ' Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS) : protocol for a randomised, controlled trial-surgery as first-line treatment ', BMJ Open, vol. 12, no. 3, e054236, pp. e054236 . https://doi.org/10.1136/bmjopen-2021-054236
Christensen, T D, Bendixen, M, Skaarup, S H, Jensen, J-U, Petersen, R H, Christensen, M, Licht, P, Neckelmann, K, Bibby, B M, Møller, L B, Bodtger, U, Borg, M H, Saghir, Z, Langfeldt, S, Harders, S M W, Bedawi, E O, Naidu, B, Rahman, N & Laursen, C B 2022, ' Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS) : protocol for a randomised, controlled trial-surgery as first-line treatment ', BMJ Open, vol. 12, no. 3, 054236 . https://doi.org/10.1136/bmjopen-2021-054236
Christensen, T D, Bendixen, M, Skaarup, S H, Jensen, J U, Petersen, R H, Christensen, M, Licht, P, Neckelmann, K, Bibby, B M, Møller, L B, Bodtger, U, Borg, M H, Saghir, Z, Langfeldt, S, Harders, S M W, Bedawi, E O, Naidu, B, Rahman, N & Laursen, C B 2022, ' Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS) : Protocol for a randomised, controlled trial-Surgery as first-line treatment ', BMJ Open, vol. 12, no. 3, e054236 . https://doi.org/10.1136/bmjopen-2021-054236
Christensen, T D, Bendixen, M, Skaarup, S H, Jensen, J-U, Petersen, R H, Christensen, M, Licht, P, Neckelmann, K, Bibby, B M, Møller, L B, Bodtger, U, Borg, M H, Saghir, Z, Langfeldt, S, Harders, S M W, Bedawi, E O, Naidu, B, Rahman, N & Laursen, C B 2022, ' Intrapleural fibrinolysis and DNase versus video-assisted thoracic surgery (VATS) for the treatment of pleural empyema (FIVERVATS) : protocol for a randomised, controlled trial-surgery as first-line treatment ', BMJ Open, vol. 12, no. 3, e054236 . https://doi.org/10.1136/bmjopen-2021-054236

IntroductionPleural empyema is a frequent disease with a high morbidity and mortality. Current standard treatment includes antibiotics and thoracic ultrasound (TUS)-guided pigtail drainage. Simultaneously with drainage, an intrapleural fibrinolyticum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27665001748b0badaa6bea3f256f59d8
https://vbn.aau.dk/da/publications/08ea271d-8e44-4a0a-a97d-9921aa62721d

Novel chimeric antigen receptors for the effective and safe treatment of NY‐BR‐1 positive breast cancer

Autor: Dirk Jäger, Aileen Berger, Alexandra Tuch, Claudia Luckner‐Minden, Rosa Eurich, Mario Hlevnjak, Andreas Schneeweiss, Peter Lichter, Sebastian Aulmann, Claus‐Peter Heussel, Carlo Fremd, Richard Harbottle, Inka Zörnig, Patrick Schmidt

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)

Externí odkaz: https://doaj.org/article/d760168d1320416e85cdc19cb58e2a0d

Assessing evidence on the impacts of nature-based interventions for climate change mitigation: a systematic map of primary and secondary research from subtropical and tropical terrestrial regions

Autor: Samantha H. Cheng, Sebastien Costedoat, Amanda Sigouin, Gabriel F. Calistro, Catherine J. Chamberlain, Peter Lichtenthal, Morena Mills, A. Justin Nowakowski, Eleanor J. Sterling, Jen Tinsman, Meredith Wiggins, Pedro H. S. Brancalion, Steven W. J. Canty, Allison Fritts-Penniman, Arundhati Jagadish, Kelly Jones, Michael B. Mascia, Ana Porzecanski, Chris Zganjar, Carlos L. Muñoz Brenes

Publikováno v: Environmental Evidence, Vol 12, Iss 1, Pp 1-26 (2023)

Abstract Background Nature-based interventions (NbIs) for climate change mitigation include a diverse set of interventions aimed at conserving, restoring, and/or managing natural and modified ecosystems to improve their ability to store and sequester

Externí odkaz: https://doaj.org/article/b1be34b9165b42b3aee65da201c272e1

Time-resolved, integrated analysis of clonally evolving genomes.

Autor: Carine Legrand, Ranja Andriantsoa, Peter Lichter, Günter Raddatz, Frank Lyko

Publikováno v: PLoS Genetics, Vol 19, Iss 12, p e1011085 (2023)

Clonal genome evolution is a key feature of asexually reproducing species and human cancer development. While many studies have described the landscapes of clonal genome evolution in cancer, few determine the underlying evolutionary parameters from m

Externí odkaz: https://doaj.org/article/50e47cc2b4274bb3be0eb5ef3ee593f4