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Autor:
Medora M. Hardy, Kevin S. Chinn, Alice P. Pentland, Peter LaCelle, Catherine S. Tripp, Eric A.G. Blomme
Publikováno v:
Journal of Investigative Dermatology. 121:853-861
The cyclooxygenase isoforms, COX-1 and COX-2, are involved in the biosynthesis of prostaglandin E2, a major prostaglandin involved in epidermal homeostasis and repair. Cancer originating in the epidermis can develop when keratinocyte proliferation an